Immune checkpoint inhibitors: a milestone in the treatment of melanoma

scientific article published on July 2016

Immune checkpoint inhibitors: a milestone in the treatment of melanoma is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1111/DDG.13012_G
P698PubMed publication ID27373242

P2093author name stringStephan Grabbe
Peter Mohr
Berenice M Lang
Sophia M Wilden
P2860cites workSafety, activity, and immune correlates of anti-PD-1 antibody in cancerQ24633070
Nivolumab plus ipilimumab in advanced melanomaQ27852310
Combined vemurafenib and cobimetinib in BRAF-mutated melanomaQ27853076
Improved overall survival in melanoma with combined dabrafenib and trametinibQ27853091
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
PD-1 and its ligands in tolerance and immunityQ28131650
Hepatotoxicity with combination of vemurafenib and ipilimumabQ28288255
Phase II DeCOG-study of ipilimumab in pretreated and treatment-naïve patients with metastatic uveal melanomaQ28543960
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated MelanomaQ29615443
Pembrolizumab versus Ipilimumab in Advanced MelanomaQ29618134
Immunologic correlates of the abscopal effect in a patient with melanomaQ29620334
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumabQ29620596
Nivolumab and ipilimumab versus ipilimumab in untreated melanomaQ29620657
Nivolumab in previously untreated melanoma without BRAF mutationQ29620688
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trialQ29620814
Clinical experience with ipilimumab 3 mg/kg: real-world efficacy and safety data from an expanded access programme cohortQ30828178
Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic MelanomaQ30890582
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial.Q33421351
Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: lymphocyte count after 2 doses correlates with survivalQ34048270
Combined BRAF (Dabrafenib) and MEK inhibition (Trametinib) in patients with BRAFV600-mutant melanoma experiencing progression with single-agent BRAF inhibitorQ34484174
Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4Q34567635
Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trialQ34670965
Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumabQ35289145
Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pretreated patients with different subtypes of metastatic melanoma.Q36256712
Genomic correlates of response to CTLA-4 blockade in metastatic melanomaQ37319470
Ipilimumab and radiation therapy for melanoma brain metastasesQ37481186
Anti-CTLA-4 antibody therapy: immune monitoring during clinical development of a novel immunotherapyQ37809156
Immunomodulating antibodies in the treatment of metastatic melanoma: the experience with anti-CTLA-4, anti-CD137, and anti-PD1.Q38004628
Immunotherapy and radiation therapy: considerations for successfully combining radiation into the paradigm of immuno-oncology drug developmentQ38227203
Clinical blockade of PD1 and LAG3--potential mechanisms of actionQ38298241
Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trialQ38404655
Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potentialQ38414485
Immunologic correlates in the course of treatment with immunomodulating antibodiesQ38475103
Targeting oncogenic BRAF and aberrant MAPK activation in the treatment of cutaneous melanoma.Q38584434
Ipilimumab Therapy in Patients With Advanced Melanoma and Preexisting Autoimmune Disorders.Q38657957
Rapid complete response of metastatic melanoma in a patient undergoing ipilimumab immunotherapy in the setting of active ulcerative colitis.Q39004691
Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: detailed safety analysis from a phase 3 trial in patients with advanced melanomaQ46110144
Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b studyQ46570875
Cutting Edge: CTLA-4 on Effector T Cells Inhibits In TransQ56888747
Immunological and biological changes during ipilimumab treatment and their potential correlation with clinical response and survival in patients with advanced melanomaQ57781473
P433issue7
P304page(s)685-695
P577publication date2016-07-01
P1433published inJDDGQ15753048
P1476titleImmune checkpoint inhibitors: a milestone in the treatment of melanoma
P478volume14

Reverse relations

cites work (P2860)
Q38860973Abl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma
Q93007229Modulating Tumor Cell Functions by Tunable Nanopatterned Ligand Presentation
Q47290990Pembrolizumab Utilization and Outcomes for Advanced Melanoma in US Community Oncology Practices
Q64082865RNAi-Mediated PD-L1 Inhibition for Pancreatic Cancer Immunotherapy
Q52758918Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients.

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