Hsa-miR-27a is involved in the regulation of CYP3A4 expression in human livers from Chinese Han population

scientific article published on 31 July 2015

Hsa-miR-27a is involved in the regulation of CYP3A4 expression in human livers from Chinese Han population is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2217/PGS.15.82
P698PubMed publication ID26229046
P5875ResearchGate publication ID280582143

P50authorZhiyun WeiQ61268459
P2093author name stringLu Shen
Lin He
Shengying Qin
Lirong Zhang
Qinghe Xing
Yichen Liu
Ye Shi
Yiting Zhang
Songshan Jiang
Yuyu Xiong
P2860cites workTranscriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gammaQ24299883
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactionsQ24310512
Understanding the mechanism of cytochrome P450 3A4: recent advances and remaining problemsQ26861370
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Genetic contribution to variable human CYP3A-mediated metabolismQ28212042
Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptorQ28215455
CYP3A gene expression in human gut epitheliumQ28236591
Cytochrome P-450 3A4: regulation and role in drug metabolismQ33636632
No correlation of hsa-miR-148a with expression of PXR or CYP3A4 in human livers from Chinese Han population.Q34634718
Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspectsQ34713638
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and manQ35580014
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liverQ36174736
Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumorsQ36294516
Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" ProblemQ36634077
Transcriptional regulation and expression of CYP3A4 in hepatocytes.Q36737747
Incidence and risk factors of retinopathy of prematurity in two neonatal intensive care units in North and South ChinaQ36804887
DIANA-microT web server: elucidating microRNA functions through target predictionQ37245804
Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expressionQ37367800
MicroRNAs regulate CYP3A4 expression via direct and indirect targetingQ37402750
The effect of microRNAs in the regulation of human CYP3A4: a systematic study using a mathematical modelQ37617645
microRNAs miR-27a and miR-27b directly regulate liver dihydropyrimidine dehydrogenase expression through two conserved binding sitesQ37637668
Genetics, epigenetics, and regulation of drug-metabolizing cytochrome p450 enzymes.Q38160337
Regulation of cytochrome b5 expression by miR-223 in human liver: effects on cytochrome P450 activities.Q39089977
Adipose tissue-secreted miR-27a promotes liver cancer by targeting FOXO1 in obese individuals.Q39623624
Dual roles of nuclear receptor liver X receptor α (LXRα) in the CYP3A4 expression in human hepatocytes as a positive and negative regulatorQ42439434
A new era in the study of individual differences in drug metabolism and pharmacokinetics.Q45329275
Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.Q46759040
miRNA27a is a biomarker for predicting chemosensitivity and prognosis in metastatic or recurrent gastric cancer.Q54239648
Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration methodQ57591671
P433issue12
P304page(s)1379-1386
P577publication date2015-07-31
P1433published inPharmacogenomicsQ15724625
P1476titleHsa-miR-27a is involved in the regulation of CYP3A4 expression in human livers from Chinese Han population
P478volume16

Reverse relations

cites work (P2860)
Q41477279MiRNA-target network analysis identifies potential biomarkers for Traditional Chinese Medicine (TCM) syndrome development evaluation in hepatitis B caused liver cirrhosis
Q28079075MiRNAs and miRNA Polymorphisms Modify Drug Response
Q90128075MicroRNA Mediated Changes in Drug Metabolism and Target Gene Expression by Efavirenz and Rifampicin In Vitro: Clinical Implications
Q51552991Plasma miR-142 accounting for the missing heritability of CYP3A4/5 functionality is associated with pharmacokinetics of clopidogrel.
Q49668137Regulation of UGT1A expression by miR-298 in human livers from the Han Chinese population and in human cell lines
Q91876482Regulation of cytochrome P450 expression by microRNAs and long noncoding RNAs: Epigenetic mechanisms in environmental toxicology and carcinogenesis

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