The Gut as an Endocrine Organ: Role in the Regulation of Food Intake and Body Weight

scientific article published on August 2016

The Gut as an Endocrine Organ: Role in the Regulation of Food Intake and Body Weight is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1007592751
P356DOI10.1007/S11883-016-0599-9
P698PubMed publication ID27324637

P2093author name stringCarel W le Roux
Neil G Docherty
Audrey Melvin
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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activationQ28290455
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Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding.Q28659292
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Gut hormone PYY(3-36) physiologically inhibits food intakeQ34143493
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Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistanceQ34456568
GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-contQ34511743
Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humansQ34511955
Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway.Q34514373
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Roux-en-Y Gastric Bypass Surgery Increases Respiratory Quotient and Energy Expenditure during Food Intake.Q35670800
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Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetesQ36240979
Brainstem nutrient sensing in the nucleus of the solitary tract inhibits feeding.Q36510898
FGF 19 and Bile Acids Increase Following Roux-en-Y Gastric Bypass but Not After Medical Management in Patients with Type 2 DiabetesQ36573090
Gastric bypass surgery vs intensive lifestyle and medical intervention for type 2 diabetes: the CROSSROADS randomised controlled trialQ36784428
Link Between Increased Satiety Gut Hormones and Reduced Food Reward After Gastric Bypass Surgery for ObesityQ36935411
Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanismsQ37125945
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humansQ37377728
Differential effects of laparoscopic sleeve gastrectomy and laparoscopic gastric bypass on appetite, circulating acyl-ghrelin, peptide YY3-36 and active GLP-1 levels in non-diabetic humansQ37471710
GOAT: the master switch for the ghrelin system?Q37737473
GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanismQ37826478
ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptorsQ38343331
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Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasiaQ38686646
Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent mannerQ40011175
EnteroglucagonQ41387845
Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell lineQ41539691
The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin.Q42255930
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Glucagon-like peptide-1 7-36: a physiological incretin in man.Q43623564
Ghrelin enhances appetite and increases food intake in humansQ43819888
Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI).Q43962935
Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structureQ44072283
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in ratsQ44165158
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Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cellsQ44758175
Effect of macronutrient composition on postprandial peptide YY levelsQ44931834
Endoscopic duodenal-jejunal bypass liner rapidly improves type 2 diabetes.Q45092471
Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY, and insulinQ45105936
PYY3-36 and pancreatic polypeptide reduce food intake in an additive manner via distinct hypothalamic dependent pathways in miceQ45716976
Effects of rectal administration of taurocholic acid on glucagon-like peptide-1 and peptide YY secretion in healthy humans.Q46011128
The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathwayQ46464837
Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study.Q47239778
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Long-term persistence of hormonal adaptations to weight lossQ47347342
Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parametersQ47356520
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight ManagementQ47377383
Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditureQ47945051
Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanismQ47963424
The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors.Q47996706
Coexpression of Agrp and NPY in fasting-activated hypothalamic neuronsQ48242769
Characterization of blood-brain barrier permeability to PYY3-36 in the mouseQ48308433
PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in ratsQ48540815
GLP-1 receptor activation modulates appetite- and reward-related brain areas in humansQ48632540
Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men.Q48714353
A novel endoscopic delivery system for placement of a duodenal-jejunal implant for the treatment of obesity and type 2 diabetesQ48861303
Glucagon-like peptide-1 receptor (GLP1-R) mRNA in the rat hypothalamusQ48883013
The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in ratsQ49036890
Impact of Duodenal-Jejunal Exclusion on Satiety Hormones.Q50560792
The effect of bariatric surgery on intestinal absorption and transit time.Q51329344
Oxyntomodulin from distal gut. Role in regulation of gastric and pancreatic functions.Q51619791
Laparoscopic gastric bypass: development of technique, respiratory function, and long-term outcome.Q51664983
Alterations of global gastrointestinal motility after sleeve gastrectomy: a prospective studyQ57112006
PYY modulation of cortical and hypothalamic brain areas predicts feeding behaviour in humansQ57978507
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide IQ58012594
Distribution and Immunocytochemical Colocalization of Peptide YY and Enteroglucagon in Endocrine Cells of the Rabbit Colon*Q68304730
Glucagon-37 (oxyntomodulin) and glucagon-29 (pancreatic glucagon) in human bowel: analysis by HPLC and radioreceptorassayQ70598950
Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36Q72125991
[Proteolytic processing by dipeptidyl aminopeptidase IV generates receptor selectivity for peptide YY (PYY)]Q72216354
P433issue8
P304page(s)49
P577publication date2016-08-01
P1433published inCurrent Atherosclerosis ReportsQ20821076
P1476titleThe Gut as an Endocrine Organ: Role in the Regulation of Food Intake and Body Weight
P478volume18

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cites work (P2860)
Q37740010Control of Food Intake by Gastrointestinal Peptides: Mechanisms of Action and Possible Modulation in the Treatment of Obesity
Q90378259ISX-9 manipulates endocrine progenitor fate revealing conserved intestinal lineages in mouse and human organoids
Q30238919Novel Browning Agents, Mechanisms, and Therapeutic Potentials of Brown Adipose Tissue.

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