| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1052118465 |
| P356 | DOI | 10.1007/S11926-016-0591-Y |
| P698 | PubMed publication ID | 27289467 |
| P2093 | author name string | Ashok Kumar | |
| Ali Mobasheri | |||
| Mona Dvir-Ginzberg | |||
| P2860 | cites work | The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase | Q24296836 |
| SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells | Q24301843 | ||
| Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis | Q24322804 | ||
| Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes | Q24645537 | ||
| SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress | Q24670578 | ||
| Osteoarthritis year in review 2015: soluble biomarkers and the BIPED criteria | Q26771893 | ||
| Inflammation and intracellular metabolism: new targets in OA | Q26777620 | ||
| The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability | Q27937288 | ||
| Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes | Q28118732 | ||
| The sirtuin SIRT6 regulates lifespan in male mice | Q28260687 | ||
| Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha | Q28274682 | ||
| Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence | Q28508751 | ||
| Microtubule deacetylases, SirT2 and HDAC6, in the nervous system | Q28510189 | ||
| Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1 | Q28512371 | ||
| Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity | Q28583282 | ||
| SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle | Q28592294 | ||
| SIRT1 transgenic mice show phenotypes resembling calorie restriction | Q29301793 | ||
| Mammalian sirtuins: biological insights and disease relevance | Q29614496 | ||
| Extrachromosomal rDNA circles--a cause of aging in yeast | Q29618308 | ||
| SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts. | Q42455903 | ||
| SIRT1 regulation of apoptosis of human chondrocytes | Q43284360 | ||
| Overexpression of sirtuin 6 suppresses inflammatory responses and bone destruction in mice with collagen-induced arthritis | Q44447800 | ||
| Sirt2 suppresses inflammatory responses in collagen-induced arthritis | Q44618444 | ||
| Nicotinamide phosphoribosyltransferase/visfatin expression by inflammatory monocytes mediates arthritis pathogenesis. | Q45950376 | ||
| Reciprocal regulation by hypoxia-inducible factor-2α and the NAMPT-NAD(+)-SIRT axis in articular chondrocytes is involved in osteoarthritis | Q46280438 | ||
| The individual and socioeconomic impact of osteoarthritis | Q47602911 | ||
| Set7/9 impacts COL2A1 expression through binding and repression of SirT1 histone deacetylation | Q47965829 | ||
| Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice. | Q50948674 | ||
| Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor. | Q51408896 | ||
| Oxidative stress induces senescence in chondrocytes. | Q53270994 | ||
| Intra-articular resveratrol injection prevents osteoarthritis progression in a mouse model by activating SIRT1 and thereby silencing HIF-2α. | Q53595543 | ||
| Simvastatin inhibits cysteine-rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin-1/FoxO3a signaling | Q57868176 | ||
| Comparison of naproxen and acetaminophen in a two-year study of treatment of osteoarthritis of the knee | Q72547388 | ||
| A two-year, placebo-controlled trial of non-steroidal anti-inflammatory therapy in osteoarthritis of the knee joint | Q72851564 | ||
| Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions | Q83452293 | ||
| SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance | Q84531194 | ||
| The overexpression of SIRT1 inhibited osteoarthritic gene expression changes induced by interleukin-1β in human chondrocytes | Q85411133 | ||
| Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling | Q85505080 | ||
| Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase | Q33569707 | ||
| Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model | Q33893466 | ||
| Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells | Q34070378 | ||
| SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. | Q34072652 | ||
| Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells | Q34494270 | ||
| SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells | Q34684132 | ||
| Sirt1-deficient mice exhibit an altered cartilage phenotype | Q34889561 | ||
| SnapShot: Mammalian Sirtuins. | Q35111981 | ||
| NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis | Q35135460 | ||
| Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling | Q35150292 | ||
| Tumor necrosis factor α-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes | Q35215468 | ||
| Detecting cathepsin activity in human osteoarthritis via activity-based probes. | Q35556209 | ||
| The pathophysiology of osteoarthritis | Q35619398 | ||
| Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes | Q36084973 | ||
| Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development | Q36350151 | ||
| Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice. | Q36390894 | ||
| Osteoarthritis year in review 2015: biology | Q36409339 | ||
| Biological markers in osteoarthritis | Q36835538 | ||
| Acetylation reduces SOX9 nuclear entry and ACAN gene transactivation in human chondrocytes. | Q36863764 | ||
| Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase. | Q37021544 | ||
| SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress. | Q37150520 | ||
| SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway | Q37179916 | ||
| Osteoarthritis year 2012 in review: biomarkers | Q38030308 | ||
| Seven sirtuins for seven deadly diseases of aging | Q38056043 | ||
| PGC1α and mitochondrial metabolism--emerging concepts and relevance in ageing and neurodegenerative disorders | Q38070667 | ||
| Emerging pathways and promising agents with possible disease modifying effect in osteoarthritis treatment | Q38193534 | ||
| Chondrosenescence: definition, hallmarks and potential role in the pathogenesis of osteoarthritis | Q38338692 | ||
| The effect of resveratrol on normal and osteoarthritic chondrocyte metabolism | Q38427475 | ||
| Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain | Q38646694 | ||
| Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis. | Q38649096 | ||
| Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling | Q39073514 | ||
| Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway | Q39364017 | ||
| Prevalence of overweight and obesity in rural and urban settings of 10 European countries. | Q39783813 | ||
| TNFα Regulates SIRT1 Cleavage during Ocular Autoimmune Disease. | Q41224675 | ||
| SIRT1 Plays a Protective Role in Intervertebral Disc Degeneration in a Puncture-induced Rodent Model | Q41487251 | ||
| Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor γ coactivator 1α | Q42176724 | ||
| Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis | Q42319037 | ||
| P2507 | corrigendum / erratum | Erratum to: The Role of Sirtuins in Cartilage Homeostasis and Osteoarthritis. | Q53795336 |
| P433 | issue | 7 | |
| P304 | page(s) | 43 | |
| P577 | publication date | 2016-07-01 | |
| P1433 | published in | Current Rheumatology Reports | Q23930052 |
| P1476 | title | The Role of Sirtuins in Cartilage Homeostasis and Osteoarthritis | |
| P478 | volume | 18 |
| Q90385503 | Activation of AMPK-SIRT3 signaling is chondroprotective by preserving mitochondrial DNA integrity and function |
| Q33827165 | DOT1L safeguards cartilage homeostasis and protects against osteoarthritis. |
| Q46035301 | Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α. |
| Q64116839 | Resveratrol inhibits IL-1β-mediated nucleus pulposus cell apoptosis through regulating the PI3K/Akt pathway |
| Q55516438 | Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis. |
| Q47097862 | SIRT1 promotes tumor-like invasion of fibroblast-like synoviocytes in rheumatoid arthritis via targeting TIMP1. |
| Q39094945 | The acetyl code in rheumatoid arthritis and other rheumatic diseases |
| Q53795336 | Erratum to: The Role of Sirtuins in Cartilage Homeostasis and Osteoarthritis. | main subject | P921 |
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