scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1001993512 |
P356 | DOI | 10.1038/ONC.2015.261 |
P932 | PMC publication ID | 4833872 |
P698 | PubMed publication ID | 26148230 |
P5875 | ResearchGate publication ID | 279807257 |
P50 | author | Joost H A Martens | Q75201047 |
P2093 | author name string | H G Stunnenberg | |
A M Sotoca | |||
A Mandoli | |||
K H M Prange | |||
L N Nguyen | |||
B Reijnders | |||
P2860 | cites work | Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics. | Q51758332 |
Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death. | Q52537887 | ||
Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice. | Q53240659 | ||
Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation. | Q53408223 | ||
Myeloid differentiation antigen and cytokine receptor expression on acute myelocytic leukaemia cells with t(16;21)(p11;q22): frequent expression of CD56 and interleukin-2 receptor alpha chain. | Q53437272 | ||
Rapid induction of CD38 antigen on myeloid leukemia cells by all trans-retinoic acid | Q72095241 | ||
Hematopoietic growth factor expression and ATRA sensitivity in acute promyelocytic blast cells | Q72454788 | ||
High FUS/TLS expression in acute myeloid leukaemia samples | Q73486050 | ||
FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cells | Q84095651 | ||
FUS/TLS forms cytoplasmic aggregates, inhibits cell growth and interacts with TDP-43 in a yeast model of amyotrophic lateral sclerosis | Q36922849 | ||
Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia | Q37226744 | ||
Genome-wide functions of PML-RARα in acute promyelocytic leukaemia | Q37829905 | ||
FUS expression alters the differentiation response to all-trans retinoic acid in NB4 and NB4R2 cells | Q38298325 | ||
Chromatin accessibility, p300, and histone acetylation define PML-RARα and AML1-ETO binding sites in acute myeloid leukemia | Q38322292 | ||
Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. | Q39649034 | ||
Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells | Q40153779 | ||
Genomic and proteomic analysis of the myeloid differentiation program | Q40790537 | ||
A topogenic role for the oncogenic N-terminus of TLS: nucleolar localization when transcription is inhibited | Q41132547 | ||
Retinoic acid-induced expression of CD38 antigen in myeloid cells is mediated through retinoic acid receptor-alpha | Q41479286 | ||
The ERGonomics of hematopoietic stem cell self-renewal | Q41834451 | ||
Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML. | Q41895366 | ||
Context-selective death of acute myeloid leukemia cells triggered by the novel hybrid retinoid-HDAC inhibitor MC2392. | Q42774706 | ||
Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia | Q43499854 | ||
Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript | Q43533951 | ||
Multiple functional domains of the oncoproteins Spi-1/PU.1 and TLS are involved in their opposite splicing effects in erythroleukemic cells | Q44830496 | ||
ERG is a megakaryocytic oncogene. | Q47677556 | ||
Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes. | Q47708383 | ||
Model-based analysis of ChIP-Seq (MACS) | Q21183902 | ||
Identification of novel functional TBP-binding sites and general factor repertoires | Q24295026 | ||
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma | Q24309359 | ||
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression | Q24313269 | ||
TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins | Q24554236 | ||
Fast and accurate short read alignment with Burrows-Wheeler transform | Q24653853 | ||
Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells | Q24669651 | ||
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. | Q27824849 | ||
The Sequence Alignment/Map format and SAMtools | Q27860966 | ||
TLS/FUS fusion domain of TLS/FUS-erg chimeric protein resulting from the t(16;21) chromosomal translocation in human myeloid leukemia functions as a transcriptional activation domain | Q28241486 | ||
TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling | Q28246694 | ||
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG | Q28252253 | ||
TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors | Q28259754 | ||
The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS | Q28262912 | ||
Role of the histone deacetylase complex in acute promyelocytic leukaemia | Q28263534 | ||
The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells | Q28281239 | ||
ERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signaling | Q28484833 | ||
TLS (Translocated-in-Liposarcoma) Is a High-Affinity Interactor for Steroid, Thyroid Hormone, and Retinoid Receptors | Q29040351 | ||
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia | Q29616211 | ||
The oncogenic TLS-ERG fusion protein exerts different effects in hematopoietic cells and fibroblasts | Q33884178 | ||
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS | Q33889532 | ||
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo | Q34000149 | ||
The ETS-domain transcription factor family | Q34066415 | ||
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia. | Q34099047 | ||
Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer | Q34612941 | ||
ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia | Q36395611 | ||
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element. | Q36802972 | ||
Establishment of a novel human acute myeloblastic leukemia cell line (YNH-1) with t(16;21), t(1;16) and 12q13 translocations | Q36853021 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International | Q24082749 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 15 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | tretinoin | Q29417 |
P304 | page(s) | 1965-1976 | |
P577 | publication date | 2015-07-06 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | The oncofusion protein FUS-ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t(16;21) acute myeloid leukemia | |
P478 | volume | 35 |
Q39058012 | AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis |
Q47117116 | Acute basophilic leukemia associated with the t(16;21)(p11;q22)/FUS-ERG fusion gene |
Q38807143 | Developmental Control of NRAMP1 (SLC11A1) Expression in Professional Phagocytes |
Q37565198 | Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. |
Q35944651 | Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells |
Q39004166 | MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia |
Q91586332 | Salvage therapy with azacitidine for pediatric acute myeloid leukemia with t(16;21)(p11;q22)/FUS-ERG and early relapse after allogeneic blood stem cell transplantation: A case report |
Q96683851 | Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer |
Q90911442 | The incidence, genetic characteristics, and prognosis of leukemia with concurrent pathogenic fusion genes: a series of 25 cases from a large cohort of leukemia patients |
Q91012693 | The role of the retinoids in schizophrenia: genomic and clinical perspectives |
Q92337654 | Transcriptional networks in acute myeloid leukemia |
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