Short Anabolic Peptides for Bone Growth

scientific article published on 28 March 2016

Short Anabolic Peptides for Bone Growth is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/MED.21388
P698PubMed publication ID27297498

P50authorMargaret BrimbleQ15848279
Zaid AmsoQ61122455
Jillian CornishQ50315176
P2860cites workIsolation and characterization of a novel endogenous peptide ligand for the human APJ receptorQ22004174
Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrumQ22010686
Ghrelin is a growth-hormone-releasing acylated peptide from stomachQ22010951
MEPE, a new gene expressed in bone marrow and tumors causing osteomalaciaQ24290092
Ghrelin and unacylated ghrelin stimulate human osteoblast growth via mitogen-activated protein kinase (MAPK)/phosphoinositide 3-kinase (PI3K) pathways in the absence of GHS-R1aQ24300324
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalizationQ24310115
Human alpha 2-macroglobulin is an osteogenic growth peptide-binding proteinQ24313039
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patientsQ24631987
Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitroQ24675778
Leaky ribosomal scanning in mammalian genomes: significance of histone H4 alternative translation in vivoQ24798502
The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretionQ28138378
Characterization of apelin, the ligand for the APJ receptorQ28141574
Galanin receptor subtypesQ28145418
The use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in orthopaedic applicationsQ28262713
Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene deliveryQ28273375
The future of peptide-based drugsQ28281702
Apelin and its receptor are expressed in human osteoblastsQ28303722
Hepcidin deficiency undermines bone load-bearing capacity through inducing iron overloadQ28507401
The receptor attributable to C-type natriuretic peptide-induced differentiation of osteoblasts is switched from type B- to type C-natriuretic peptide receptor with agingQ28571552
Substance P stimulates late-stage rat osteoblastic bone formation through neurokinin-1 receptorsQ28577956
Dwarfism and early death in mice lacking C-type natriuretic peptideQ28588954
Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitroQ37251736
Anti-resorptive therapies for osteoporosis.Q37257184
Increased osteoblast functions in the presence of BMP-7 short peptides for nanostructured biomaterial applicationsQ37320869
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiationQ37339719
Teriparatide: a review of its use in osteoporosis.Q37354140
Priming integrin alpha5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis.Q37413484
Targeting the ghrelin receptor to regulate food intakeQ37442033
Osteogenic differentiation of human mesenchymal stem cells on α5 integrin binding peptide hydrogels is dependent on substrate elasticityQ37649448
Osteoporosis: impact on health and economicsQ37686083
IGF-IEc expression, regulation and biological function in different tissuesQ37759904
Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousalQ37874775
Parathyroid hormone analogues in the treatment of osteoporosisQ37900475
New understanding and treatments for osteoporosisQ37969683
The role of ghrelin in the control of energy balanceQ37976357
Iron homeostasis in osteoporosis and its clinical implicationsQ38004771
Mechanisms in endocrinology: Ghrelin: the differences between acyl- and des-acyl ghrelinQ38035140
Targeting integrins to promote bone formation and repairQ38077443
Literature review: The effects of teriparatide therapy at the hip in patients with osteoporosisQ38232951
Ghrelin is an Osteoblast Mitogen and Increases Osteoclastic Bone Resorption In VitroQ38345504
Endothelin-1 promotes osteoprogenitor proliferation and differentiation in fetal rat calvarial cell culturesQ38349359
Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1-31)NH(2)] in postmenopausal women with osteoporosisQ38459806
Functional expression of N-formyl peptide receptors in human bone marrow-derived mesenchymal stem cellsQ38464455
Short-term and long-term effects of osteoporosis therapies.Q38473594
Functional and transcriptomic analysis of the regulation of osteoblasts by mechano-growth factor E peptideQ38485815
Improving the osteogenic efficacy of BMP2 with mechano growth factor by regulating the signaling events in BMP pathwayQ38890787
Wnt/β-catenin signaling mediates osteoblast differentiation triggered by peptide-induced α5β1 integrin priming in mesenchymal skeletal cellsQ38915530
Selective osteogenesis by a synthetic mineral inducing peptide for the treatment of osteoporosisQ38957931
Pituitary adenylate cyclase-activating polypeptide (PACAP) signalling enhances osteogenesis in UMR-106 cell line.Q38967086
Effects of mouse hepcidin 1 treatment on osteoclast differentiation and intracellular iron concentrationQ38972072
The proteasome inhibitor bortezomib stimulates osteoblastic differentiation of human osteoblast precursors via upregulation of vitamin D receptor signallingQ39212192
Regulation of osteoblastic differentiation by the proteasome inhibitor bortezomibQ39330638
New cyclic peptides with osteoblastic proliferative activity from Dianthus superbusQ39398084
Mechano-growth factor E peptide inhibits the differentiation and mineralization of osteoblastsQ39425012
An isolated cryptic peptide influences osteogenesis and bone remodeling in an adult mammalian model of digit amputationQ39440583
Hepcidin increases intracellular Ca2+ of osteoblast hFOB1.19 through L-type Ca2+ channelsQ39475421
Ghrelin directly regulates bone formation.Q51504751
First-in-human testing of a wirelessly controlled drug delivery microchip.Q51541952
Effect of varied release kinetics of the osteogenic thrombin peptide TP508 from biodegradable, polymeric scaffolds on bone formation in vivo.Q51550160
Repair of rabbit segmental defects with the thrombin peptide, TP508.Q51633187
The evaluation of ectopic bone formation induced by delivery systems for bone morphogenetic protein-9 or its derived peptide.Q51765433
Presence of galanin-like immunoreactivity in mesenchymal and neural crest origin tissues during embryonic development in the mouse.Q51784331
Skeletal analysis of the long bone abnormality (lbab/lbab) mouse, a novel chondrodysplastic C-type natriuretic peptide mutant.Q51822129
Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation.Q52178500
Cloning and characterization of an IGF-1 isoform expressed in skeletal muscle subjected to stretch.Q52200362
Gene expression of bone matrix proteins and endothelin receptors in endothelin-1-deficient mice revealed by in situ hybridization.Q52529454
The effect of bone morphogenetic protein-2, bone morphogenetic protein-7, parathyroid hormone, and platelet-derived growth factor on the proliferation and osteogenic differentiation of mesenchymal stem cells derived from osteoporotic bone.Q52847181
The influence of growth hormone deficiency, growth hormone replacement therapy, and other aspects of hypopituitarism on fracture rate and bone mineral density. .Q53328360
The use of immobilized osteogenic growth peptide on gradient substrates synthesized via click chemistry to enhance MC3T3-E1 osteoblast proliferation.Q53358642
Biomimetic surface modification using synthetic oligopeptides for enhanced guided bone regeneration in beagles.Q53426429
The identification of a heparin binding domain peptide from bone morphogenetic protein-4 and its role on osteogenesis.Q53464974
Increased Bone Turnover and Possible Accelerated Fracture Healing in a Murine Model With an Increased Circulating C-Type Natriuretic Peptide.Q53550819
rhBMP-2, rhVEGF(165), rhPTN and thrombin-related peptide, TP508 induce chemotaxis of human osteoblasts and microvascular endothelial cells.Q53622168
Bone formation is enhanced by thrombin-related peptide TP508 during distraction osteogenesis.Q53629243
Bone formation on two-dimensional poly(DL-lactide-co-glycolide) (PLGA) films and three-dimensional PLGA tissue engineering scaffolds in vitro.Q54023207
Peptide-based activation of alpha5 integrin for promoting osteogenesis.Q54311172
Synthetic osteogenic growth peptide promotes differentiation of human bone marrow mesenchymal stem cells to osteoblasts via RhoA/ROCK pathway.Q54575678
Effects of abaloparatide, a human parathyroid hormone-related peptide analog, on bone mineral density in postmenopausal women with osteoporosis.Q55058660
Central and peripheral expression of galanin in response to inflammationQ57990477
Molecular Basis of Ligand Recognition by Integrin α5β1Q58057976
Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action.Q43771278
Monthly administration of a novel PTH-collagen binding domain fusion protein is anabolic in miceQ43974287
Dentonin, a fragment of MEPE, enhanced dental pulp stem cell proliferationQ44137977
How to blast osteoblasts? Novel dicarba analogues of amylin-(1-8) to treat osteoporosisQ44243006
Expression and Splicing of the Insulin‐Like Growth Factor Gene in Rodent Muscle is Associated with Muscle Satellite (stem) Cell Activation following Local Tissue DamageQ44401232
Bone induction by biomimetic PLGA-(PEG-ASP)n copolymer loaded with a novel synthetic BMP-2-related peptide in vitro and in vivoQ44546612
Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolismQ44605245
Amylin fasting plasma levels are decreased in patients with osteoporosisQ44647489
Effects and differentiation activity of IGF-I, IGF-II, insulin and preptin on human primary bone cells.Q44650839
A synthetic peptide fragment of human MEPE stimulates new bone formation in vitro and in vivoQ44812046
Ala-scan of ghrelin (1-14): interaction with the recombinant human ghrelin receptorQ44941270
A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase-2 to exert potent anabolic effects on normal human marrow osteoblast precursorsQ45078877
Connective tissue growth factor is a downstream mediator for preptin-induced proliferation and differentiation in human osteoblastsQ45158996
Ghrelin regulates proliferation and differentiation of osteoblastic cells.Q45218899
Characterization of new stable ghrelin analogs with prolonged orexigenic potencyQ45249630
Preparation and ectopic osteogenesis in vivo of scaffold based on mineralized recombinant human-like collagen loaded with synthetic BMP-2-derived peptideQ45771355
Lentiviral-mediated integrin α5 expression in human adult mesenchymal stromal cells promotes bone repair in mouse cranial and long-bone defectsQ45873674
Organization and expression analysis of the zebrafish hepcidin gene, an antimicrobial peptide gene conserved among vertebrates.Q45956866
Postmenopausal women with osteoporosis may be associated with high endothelin-1.Q45969308
Murine preosteoblast differentiation induced by a peptide derived from bone morphogenetic proteins-9.Q46039342
Enhanced cell attachment to anorganic bone mineral in the presence of a synthetic peptide related to collagenQ46125345
Parathyroid hormone (1-34)-coated microneedle patch system: clinical pharmacokinetics and pharmacodynamics for treatment of osteoporosisQ46139256
Assembly of collagen-binding peptide with collagen as a bioactive scaffold for osteogenesis in vitro and in vivoQ46279649
Early gene and protein expression associated with osteoblast differentiation in response to fish collagen peptides powderQ46288506
Neuro-hormonal control of bone metabolism: vasoactive intestinal peptide stimulates alkaline phosphatase activity and mRNA expression in mouse calvarial osteoblasts as well as calcium accumulation mineralized bone nodulesQ46290538
Correlation between induction of expression of biglycan and mineralization by C-type natriuretic peptide in osteoblastic cells.Q46291320
Amylin stimulates osteoblast proliferation and increases mineralized bone volume in adult miceQ46294704
Enhanced cell attachment and osteoblastic activity by P-15 peptide-coated matrix in hydrogelsQ46497508
Osteogenesis induced by a bone forming peptide from the prodomain region of BMP-7.Q46505734
Proteasome inhibitors abrogate osteoclast differentiation and osteoclast functionQ46528690
Stimulation of intramembranous bone repair in rats by ghrelin.Q46533401
Pulse treatment with the proteasome inhibitor bortezomib inhibits osteoclast resorptive activity in clinically relevant conditionsQ46659830
The potential impact of new National Osteoporosis Foundation guidance on treatment patternsQ46676022
Response to bortezomib is associated to osteoblastic activation in patients with multiple myelomaQ46712881
Immobilization of a bone and cartilage stimulating peptide to a synthetic bone graftQ46887966
Osteogenic growth peptide modulates fracture callus structural and mechanical propertiesQ47318273
Bone neoplasms in F344 rats given teriparatide [rhPTH(1-34)] are dependent on duration of treatment and doseQ47325378
Osteogenic growth peptide incorporated into PLGA scaffolds accelerates healing of segmental long bone defects in rabbitsQ47418503
MAP kinase signaling cascades and gene expression in osteoblastsQ47774538
Differential effects of natriuretic peptide stimulation on tissue-engineered cartilageQ47853606
Multi-center clinical evaluation of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) as a bone replacement graft material in human periodontal osseous defects. 6-month resultsQ47861122
Potential impact of sitagliptin on collagen-derived dipeptides in diabetic osteoporosis.Q47909401
Lack of an acute effect of ghrelin on markers of bone turnover in healthy controls and post-gastrectomy subjectsQ48114511
Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organsQ48311650
C-type natriuretic peptide (CNP): a new member of natriuretic peptide family identified in porcine brain.Q49017266
Bortezomib enhances the osteogenic differentiation capacity of human mesenchymal stromal cells derived from bone marrow and placental tissues.Q50473451
Effects of egg yolk-derived peptide on osteogenic gene expression and MAPK activation.Q50638721
ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion.Q50797268
Local injection of thrombin-related peptide (TP508) in PPF/PLGA microparticles-enhanced bone formation during distraction osteogenesis.Q50878490
Innervation of periosteum and bone by sympathetic vasoactive intestinal peptide-containing nerve fibers.Q50909472
Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication.Q50946373
Experimental research on ectopic osteogenesis of BMP2-derived peptide P24 combined with PLGA copolymers.Q51006336
Injectable gel with synthetic collagen-binding peptide for enhanced osteogenesis in vitro and in vivo.Q51028637
Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial.Q51168965
A study of biologically active peptide sequences (P-15) on the surface of an ABM scaffold (PepGen P-15) using AFM and FTIR.Q51401122
Single and combined use of human parathyroid hormone (PTH) (1-34) on areal bone mineral density (aBMD) in postmenopausal women with osteoporosis: evidence based on 9 RCTsQ34742975
Amylin and adrenomedullin: novel regulators of bone growth.Q34779817
Expression and regulatory role of receptors for vasoactive intestinal peptide in bone cellsQ34804000
Use of recombinant human bone morphogenetic protein-2 in spinal fusion applicationsQ34805764
Chronic central administration of Ghrelin increases bone mass through a mechanism independent of appetite regulation.Q34812037
N-formyl-methionyl-leucyl-phenylalanine (fMLP) promotes osteoblast differentiation via the N-formyl peptide receptor 1-mediated signaling pathway in human mesenchymal stem cells from bone marrowQ34948033
Characterization of the molecular mechanism of the bone-anabolic activity of carfilzomib in multiple myelomaQ34997270
Significance of C-type natriuretic peptide (CNP) in endochondral ossification: analysis of CNP knockout miceQ34998675
Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery.Q35006651
The association between the serum C-peptide level and bone mineral densityQ35072996
Teriparatide treatment patterns in osteoporosis and subsequent fracture events: a US claims analysisQ35092617
Bone morphogenetic proteins, their antagonists, and the skeletonQ35109618
Genetic determination of the cellular basis of the ghrelin-dependent bone remodelingQ35113493
Mechano growth factor E peptide promotes osteoblasts proliferation and bone-defect healing in rabbitsQ35197522
The anabolic effects of parathyroid hormone therapyQ35198551
Recruitment of progenitor cells by an extracellular matrix cryptic peptide in a mouse model of digit amputationQ35230870
Neuropeptide Y, substance P, and human bone morphogenetic protein 2 stimulate human osteoblast osteogenic activity by enhancing gap junction intercellular communication.Q35567595
Association between low C-peptide and low lumbar bone mineral density in postmenopausal women without diabetesQ35597894
Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectivesQ35744492
The Proteasome Inhibitor Carfilzomib Suppresses Parathyroid Hormone-induced Osteoclastogenesis through a RANKL-mediated Signaling PathwayQ35860566
Molecular and cellular mechanisms of the anabolic effect of intermittent PTHQ36016775
Early Effects of Single and Low-Frequency Repeated Administration of Teriparatide, hPTH(1-34), on Bone Formation and Resorption in Ovariectomized RatsQ36042959
The ABCs of BMPsQ36050270
Effects of P-15 Peptide Coated Hydroxyapatite on Tibial Defect Repair In Vivo in Normal and Osteoporotic RatsQ36174144
Mechanical signals, IGF-I gene splicing, and muscle adaptationQ36197814
Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library.Q36233759
Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functionsQ36314468
P-15 small peptide bone graft substitute in the treatment of non-unions and delayed union. A pilot clinical trialQ36495738
Osteoporosis: now and the futureQ36564425
Thrombin peptide TP508 stimulates cellular events leading to angiogenesis, revascularization, and repair of dermal and musculoskeletal tissuesQ36641786
Sixteen weeks of hexarelin therapy in aged dogs: effects on the somatotropic axis, muscle morphology, and bone metabolismQ36831972
A single injection of the anabolic bone agent, parathyroid hormone-collagen binding domain (PTH-CBD), results in sustained increases in bone mineral density for up to 12 months in normal female mice.Q36957141
The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivoQ37034189
Expression of galanin and a galanin receptor in several sensory systems and bone anlage of rat embryosQ37056101
Increased bone mass in mice lacking the adipokine apelinQ37087683
Safety of parathyroid hormone for the treatment of osteoporosisQ37145404
Growth hormone, insulin-like growth factors, and the skeletonQ37147591
The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects.Q37166798
Bortezomib induces osteoblast differentiation via Wnt-independent activation of beta-catenin/TCF signalingQ37176560
A comparison of parathyroid hormone-related protein (1-36) and parathyroid hormone (1-34) on markers of bone turnover and bone density in postmenopausal women: the PrOP studyQ37213526
Systemic administration of C-type natriuretic peptide as a novel therapeutic strategy for skeletal dysplasiasQ37244601
Developmental regulation of the growth plateQ29618969
Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosisQ29619487
How cells read TGF-beta signalsQ29619993
A novel potent vasoconstrictor peptide produced by vascular endothelial cellsQ29620540
Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formationQ30441987
Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesisQ30494322
Two years of treatment with recombinant human growth hormone increases bone mineral density in men with idiopathic osteoporosisQ30868288
The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female ratsQ30873578
Human Galanin: Molecular Cloning Reveals a Unique StructureQ33265553
Replacement of bortezomib with carfilzomib for multiple myeloma patients progressing from bortezomib combination therapyQ33412690
Substance P activates the Wnt signal transduction pathway and enhances the differentiation of mouse preosteoblastic MC3T3-E1 cellsQ33580629
Effect of transdermal teriparatide administration on bone mineral density in postmenopausal womenQ33586747
Reduced amylin levels are associated with low bone mineral density in women with anorexia nervosaQ33665366
Orexin regulates bone remodeling via a dominant positive central action and a subordinate negative peripheral actionQ33717450
Antiosteoporotic effect of orally administered yolk-derived peptides on bone mass in womenQ33723041
Update in new anabolic therapies for osteoporosisQ33786824
HDAC4 integrates PTH and sympathetic signaling in osteoblastsQ33797044
Endothelin and post-ganglionic sympathetic neuronsQ33811422
Neuropeptide substance P improves osteoblastic and angiogenic differentiation capacity of bone marrow stem cells in vitroQ33876274
Casein kinase 2 beta-subunit is a regulator of bone morphogenetic protein 2 signalingQ34032756
Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH.Q34132577
Surface immobilization of MEPE peptide onto HA/β-TCP ceramic particles enhances bone regeneration and remodeling.Q34249760
Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasiaQ34314761
The nuclear localization of MGF receptor in osteoblasts under mechanical stimulationQ34323600
Metabolism of growth hormone releasing peptidesQ34458391
Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasomeQ34501396
Lower circulating preptin levels in male patients with osteoporosis are correlated with bone mineral density and bone formationQ34567531
The neural circuit of orexin (hypocretin): maintaining sleep and wakefulnessQ34575514
Regulation of bone mass by Wnt signalingQ34576629
Proteasome inhibitors in the treatment of multiple myelomaQ34611676
In vitro cytocompatibility evaluation of MGF-Ct24E chemically grafted and physically blended with maleic anhydride modified poly(D, L-lactic acid).Q34675232
Parathyroid hormone for the treatment of osteoporosis: a systematic reviewQ34695988
TGFbeta-SMAD signal transduction: molecular specificity and functional flexibilityQ34713446
Teriparatide or alendronate in glucocorticoid-induced osteoporosisQ34713779
Casein kinase 2 regulates in vivo bone formation through its interaction with bone morphogenetic protein receptor type Ia.Q39505619
Protective effect of egg yolk peptide on bone metabolismQ39627712
C-type natriuretic peptide: Structural studies, fragment synthesis, and preliminary biological evaluation in human osteosarcoma cell lines.Q39728491
Amylin(1-8) is devoid of anabolic activity in boneQ39744641
Early osteogenic differentiation of mouse preosteoblasts induced by collagen-derived DGEA-peptide on nanofibrous phage tissue matrices.Q39779818
cAMP activation by PACAP/VIP stimulates IL-6 release and inhibits osteoblastic differentiation through VPAC2 receptor in osteoblastic MC3T3 cellsQ39842814
A novel collagen-binding peptide promotes osteogenic differentiation via Ca2+/calmodulin-dependent protein kinase II/ERK/AP-1 signaling pathway in human bone marrow-derived mesenchymal stem cellsQ40016731
Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3-E1 via JNK and PI3-K/Akt signaling pathways.Q40207646
Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasisQ40360482
Ghrelin stimulates proliferation and differentiation and inhibits apoptosis in osteoblastic MC3T3-E1 cellsQ40404949
Accelerated bone repair with the use of a synthetic BMP-2-derived peptide and bone-marrow stromal cells.Q40492043
Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system"Q40512524
Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.Q40528212
Prolonged ectopic calcification induced by BMP-2-derived synthetic peptide.Q40549773
Structure-activity studies of orexin a and orexin B at the human orexin 1 and orexin 2 receptors led to orexin 2 receptor selective and orexin 1 receptor preferring ligandsQ40588357
MEPE has the properties of an osteoblastic phosphatonin and minhibin.Q40590136
Attachment, proliferation, and migration of marrow stromal osteoblasts cultured on biomimetic hydrogels modified with an osteopontin-derived peptide.Q40618012
E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast DifferentiationQ40649010
Bioactive pseudopeptidic analogues and cyclostereoisomers of osteogenic growth peptide C-terminal pentapeptide, OGP(10-14).Q40740588
Mitogenic G(i) protein-MAP kinase signaling cascade in MC3T3-E1 osteogenic cells: activation by C-terminal pentapeptide of osteogenic growth peptide [OGP(10-14)] and attenuation of activation by cAMP.Q40809278
Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in ratsQ40809292
Ipamorelin, the first selective growth hormone secretagogueQ40832148
Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a.Q40840986
Stimulation by retinoids of the natriuretic peptide system of osteoblastic MC3T3-E1 cells.Q41155146
Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostateQ41304383
Design of biomimetic habitats for tissue engineering with P-15, a synthetic peptide analogue of collagenQ41646614
The action of GH/IGF-I/IGFBP in osteoblasts and osteoclastsQ41684793
Efficacy, effectiveness and side effects of medications used to prevent fractures.Q41704607
Biological designer self-assembling peptide nanofiber scaffolds significantly enhance osteoblast proliferation, differentiation and 3-D migrationQ41971530
The effect of collagen I mimetic peptides on mesenchymal stem cell adhesion and differentiation, and on bone formation at hydroxyapatite surfacesQ42151053
Tailored integrin-extracellular matrix interactions to direct human mesenchymal stem cell differentiationQ42287329
Expression of galanin and galanin receptor-1 in normal bone and during fracture repair in the ratQ42452930
Growth hormone stimulates proliferation and differentiation of normal human osteoblast-like cells in vitroQ42483109
Inhibitory effect of amylin on basal and parathyroid hormone-stimulated bone resorption in cultured neonatal mouse calvariaQ42505874
Bone mineral density at time of clinical diagnosis of adult-onset type 1 diabetes mellitusQ42510908
Enhanced osteogenesis by collagen-binding peptide from bone sialoprotein in vitro and in vivoQ42511847
Protective effect of apelin on cultured rat bone marrow mesenchymal stem cells against apoptosisQ42557243
Thrombin related peptide TP508 promoted fracture repair in a mouse high energy fracture modelQ42610559
The neuropeptide VIP regulates the expression of osteoclastogenic factors in osteoblastsQ42611864
Mitogenic action of osteogenic growth peptide (OGP): role of amino and carboxy-terminal regions and chargeQ42614776
Effects of teriparatide on bone mineral density and bone turnover markers in Japanese subjects with osteoporosis at high risk of fracture in a 24-month clinical study: 12-month, randomized, placebo-controlled, double-blind and 12-month open-label phQ42665480
Ghrelin inhibits the apoptosis of MC3T3-E1 cells through ERK and AKT signaling pathwayQ42710000
ETA receptor mediates the signaling of endothelin-1 in osteoblast-like cellsQ42798109
Stimulation by C-type natriuretic peptide of the differentiation of clonal osteoblastic MC3T3-E1 cellsQ42814044
Egg yolk soluble protein stimulates the proliferation and differentiation of osteoblastic MC3T3-E1 cellsQ42828567
Osteogenic growth peptide C-terminal pentapeptide [OGP(10-14)] acts on rat bone marrow mesenchymal stem cells to promote differentiation to osteoblasts and to inhibit differentiation to adipocytesQ42830500
Differentiation of preosteoblasts using a delivery system with BMPs and bioactive glass microspheresQ42830598
Neutral endopeptidase-resistant C-type natriuretic peptide variant represents a new therapeutic approach for treatment of fibroblast growth factor receptor 3-related dwarfismQ42830752
Osteopromotion with synthetic oligopeptide-coated bovine bone mineral in vivoQ42832404
Collagen-derived dipeptide prolyl-hydroxyproline promotes differentiation of MC3T3-E1 osteoblastic cellsQ42834732
C-type natriuretic peptide regulates endochondral bone growth through p38 MAP kinase-dependent and -independent pathwaysQ42861749
Osteogenic growth peptide enhances the proliferation of bone marrow mesenchymal stem cells from osteoprotegerin-deficient mice by CDK2/cyclin A.Q42868212
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.Q42918384
Relationships between serum adiponectin, apelin, leptin, resistin, visfatin levels and bone mineral density, and bone biochemical markers in post-menopausal Chinese womenQ43140284
Alkaline phosphatase variation during carfilzomib treatment is associated with best response in multiple myeloma patientsQ43409328
Changes in pituitary adenylate cyclase-activating Peptide 27-like immunoreactive nervous structures in the porcine descending colon during selected pathological processesQ43582500
Amylin and bone metabolism in streptozotocin-induced diabetic ratsQ43599982
Preptin analogues: chemical synthesis, secondary structure and biological studiesQ43703282
Structure-activity relationship of ghrelin: pharmacological study of ghrelin peptidesQ43732032
P433issue4
P304page(s)579-640
P577publication date2016-03-28
P1433published inMedicinal Research ReviewsQ2436033
P1476titleShort Anabolic Peptides for Bone Growth
P478volume36

Reverse relations

cites work (P2860)
Q53755539Structure activity relationship study on the peptide hormone preptin, a novel bone-anabolic agent for the treatment of osteoporosis.
Q53155600Synthesis and in vitro bone cell activity of analogues of the cyclohexapeptide dianthin G.

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