scholarly article | Q13442814 |
P50 | author | Antonio Mas | Q45634126 |
Francisco Jose Cimas | Q56953554 | ||
Félix A. Jalón | Q60632546 | ||
P2093 | author name string | Aimé Vazquez | |
Jesús García-Cano | |||
Leticia Serrano-Oviedo | |||
Ricardo Sánchez-Prieto | |||
Gorbatchev Ambroise | |||
María José Ruiz-Hidalgo | |||
Isabel Sanchez Perez | |||
Maria Carmen Carrión | |||
Marta Ortega-Muelas | |||
Raquel Pascual-Serra | |||
Sebastià Sabater | |||
P2860 | cites work | Guidelines for the use and interpretation of assays for monitoring autophagy | Q21996341 |
Balance between MKK6 and MKK3 mediates p38 MAPK associated resistance to cisplatin in NSCLC | Q28478252 | ||
BH3-mimetics- and cisplatin-induced cell death proceeds through different pathways depending on the availability of death-related cellular components | Q28486502 | ||
Upregulation of autophagy-related gene-5 (ATG-5) is associated with chemoresistance in human gastric cancer | Q28543901 | ||
Requirement for p53 and p21 to sustain G2 arrest after DNA damage | Q29547667 | ||
Cisplatin: mode of cytotoxic action and molecular basis of resistance | Q29615385 | ||
Identification of a novel inhibitor of mitogen-activated protein kinase kinase | Q29616448 | ||
ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor | Q29616727 | ||
3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes | Q29617843 | ||
Tumour heterogeneity and cancer cell plasticity | Q29617990 | ||
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy | Q30513775 | ||
Reduced cisplatin sensitivity of head and neck squamous cell carcinoma cell lines correlates with mutations affecting the COOH-terminal nuclear localization signal of p53. | Q33224549 | ||
Autophagy and cancer therapy | Q33584607 | ||
Synergistic killing of lung cancer cells by cisplatin and radiation via autophagy and apoptosis | Q33727550 | ||
Role of autophagy in cisplatin resistance in ovarian cancer cells | Q33761338 | ||
Concomitant inhibition of AKT and autophagy is required for efficient cisplatin-induced apoptosis of metastatic skin carcinoma. | Q33829753 | ||
Cytotoxic autophagy in cancer therapy | Q33907663 | ||
Phytochemicals: a multitargeted approach to gynecologic cancer therapy. | Q33908881 | ||
Detouring of cisplatin to access mitochondrial genome for overcoming resistance | Q33972195 | ||
Abrogation of the p38 MAPK α signaling pathway does not promote radioresistance but its activity is required for 5-Fluorouracil-associated radiosensitivity. | Q39195786 | ||
Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation | Q39353049 | ||
P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance | Q39490275 | ||
Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis | Q39520993 | ||
Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy | Q39734588 | ||
Poly(ADPR)polymerase inhibition and apoptosis induction in cDDP-treated human carcinoma cell lines | Q39983946 | ||
Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy | Q40006232 | ||
Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin | Q40195778 | ||
BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo. | Q40448987 | ||
Overexpression of BclXL in a human ovarian carcinoma cell line: paradoxic effects on chemosensitivity in vitro versus in vivo | Q40749276 | ||
Requirement for ERK activation in cisplatin-induced apoptosis | Q40854460 | ||
Inhibition of autophagy enhances cisplatin cytotoxicity through endoplasmic reticulum stress in human cervical cancer cells | Q41931397 | ||
Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics | Q41933492 | ||
Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment. | Q42442790 | ||
3-Methyladenine induces cell death and its interaction with chemotherapeutic drugs is independent of autophagy | Q42520512 | ||
A role for the p38 mitogen-acitvated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents | Q42801995 | ||
TP53 mutations and pathologic complete response to neoadjuvant cisplatin and fluorouracil chemotherapy in resected oral cavity squamous cell carcinoma. | Q43202682 | ||
Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties | Q44483506 | ||
Role of the p38 MAPK pathway in cisplatin-based therapy | Q44488190 | ||
Monofunctional platinum complexes showing potent cytotoxicity against human liver carcinoma cell line BEL-7402. | Q44523317 | ||
Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL. | Q46601653 | ||
Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance | Q53304624 | ||
Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer | Q54159355 | ||
Effects of cisplatin on the induction of apoptosis in proliferating hepatoma cells and nonproliferating immature thymocytes | Q58283085 | ||
Cisplatin in cancer therapy: molecular mechanisms of action | Q34098163 | ||
Long-term cisplatin exposure impairs autophagy and causes cisplatin resistance in human lung cancer cells | Q34141265 | ||
Synthetic lethality: General principles, utility and detection using genetic screens in human cells | Q34151015 | ||
Tailoring mTOR-based therapy: molecular evidence and clinical challenges | Q34294170 | ||
Induction of autophagy contributes to cisplatin resistance in human ovarian cancer cells | Q34540874 | ||
Ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase inhibition is synthetically lethal in XRCC1 deficient ovarian cancer cells | Q34603025 | ||
eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt Inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206. | Q35534450 | ||
NAC1 modulates sensitivity of ovarian cancer cells to cisplatin by altering the HMGB1-mediated autophagic response | Q35745292 | ||
Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence | Q36020559 | ||
Enhancement of synthetic lethality via combinations of ABT-888, a PARP inhibitor, and carboplatin in vitro and in vivo using BRCA1 and BRCA2 isogenic models | Q36552134 | ||
Autophagy in cancer: good, bad, or both? | Q36612549 | ||
Inhibition of autophagy enhances anticancer effects of bevacizumab in hepatocarcinoma | Q36725301 | ||
Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin | Q37043064 | ||
Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells. | Q37073574 | ||
Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. | Q37342850 | ||
Protective effect of metalloporphyrins against cisplatin-induced kidney injury in mice | Q37479069 | ||
Targeting cancer cells through autophagy for anticancer therapy | Q37670439 | ||
The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma | Q37689423 | ||
Molecular mechanisms of cisplatin resistance | Q37926477 | ||
Chloroquine in cancer therapy: a double-edged sword of autophagy. | Q38071618 | ||
Autophagy and cell death to target cancer cells: exploiting synthetic lethality as cancer therapies | Q38165840 | ||
The machinery of macroautophagy | Q38173673 | ||
The four faces of autophagy: implications for cancer therapy | Q38181453 | ||
Targeting the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway: an emerging treatment strategy for squamous cell lung carcinoma | Q38230994 | ||
Synthetic lethal vulnerabilities of cancer | Q38262217 | ||
Applying synthetic lethality for the selective targeting of cancer. | Q38263612 | ||
The role of DNA repair pathways in cisplatin resistant lung cancer | Q38280128 | ||
HMGB1 promotes drug resistance in osteosarcoma | Q38330106 | ||
A reversible gene-targeting strategy identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo | Q38411451 | ||
Induction of autophagy counteracts the anticancer effect of cisplatin in human esophageal cancer cells with acquired drug resistance | Q38955141 | ||
MCL-1 dependency of cisplatin-resistant cancer cells | Q38967669 | ||
Cisplatin-mediated radiosensitization of non-small cell lung cancer cells is stimulated by ATM inhibition. | Q38992228 | ||
miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells | Q39039757 | ||
Autophagy inhibition sensitizes cisplatin cytotoxicity in human gastric cancer cell line SGC7901. | Q39089314 | ||
Cisplatin-induced downregulation of SOX1 increases drug resistance by activating autophagy in non-small cell lung cancer cell | Q39101898 | ||
P433 | issue | 17 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | autophagy | Q288322 |
cisplatin | Q412415 | ||
P1104 | number of pages | 15 | |
P304 | page(s) | 15551-15565 | |
P577 | publication date | 2015-06-01 | |
P1433 | published in | Oncotarget | Q1573155 |
P1476 | title | Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance | |
P478 | volume | 6 |
Q90499083 | Autophagic cell death associated to Sorafenib in renal cell carcinoma is mediated through Akt inhibition in an ERK1/2 independent fashion |
Q38868651 | Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer |
Q42329870 | Bu-Zhong-Yi-Qi Decoction, the Water Extract of Chinese Traditional Herbal Medicine, Enhances Cisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy |
Q41516517 | DACT1 Overexpression in type I ovarian cancer inhibits malignant expansion and cis-platinum resistance by modulating canonical Wnt signalling and autophagy |
Q48533220 | DR2 blocker thioridazine: A promising drug for ovarian cancer therapy. |
Q49882954 | Drug-resistance in doxorubicin-resistant FL5.12 hematopoietic cells: elevated MDR1, drug efflux and side-population positive and decreased BCL2-family member expression |
Q52723011 | Effects of carbon ion beam alone or in combination with cisplatin on malignant mesothelioma cells in vitro. |
Q49335119 | Effects of ginkgol C17:1 on cisplatin-induced autophagy and apoptosis in HepG2 cells |
Q42022268 | Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers |
Q38810052 | MKP1 mediates chemosensitizer effects of E1a in response to cisplatin in non-small cell lung carcinoma cells. |
Q42957913 | MKP1: Jekyll and Hyde for E1A. |
Q41911898 | Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells. |
Q36962940 | Phenylethyl isothiocyanate reverses cisplatin resistance in biliary tract cancer cells via glutathionylation-dependent degradation of Mcl-1 |
Q97526399 | Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells |
Q37641631 | Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells. |
Q42261432 | Small-molecule RL71-triggered excessive autophagic cell death as a potential therapeutic strategy in triple-negative breast cancer. |
Q37432540 | Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications. |
Q40961505 | Suberoylanilide hydroxamic acid sensitizes neuroblastoma to paclitaxel by inhibiting thioredoxin-related protein 14-mediated autophagy. |
Q59125598 | Synergistic Effects of NOTCH/γ-Secretase Inhibition and Standard of Care Treatment Modalities in Non-small Cell Lung Cancer Cells |
Q47257003 | Targeting urothelial carcinoma cells by combining cisplatin with a specific inhibitor of the autophagy-inducing class III PtdIns3K complex. |
Q52363628 | Using phosphine ligands with a biological role to modulate reactivity in novel platinum complexes. |
Q38710573 | Verapamil treatment induces cytoprotective autophagy by modulating cellular metabolism |
Q38554814 | miR-222 attenuates cisplatin-induced cell death by targeting the PPP2R2A/Akt/mTOR Axis in bladder cancer cells |
Q26742078 | p38MAPK and Chemotherapy: We Always Need to Hear Both Sides of the Story |
Q55002919 | p53 and metabolism: from mechanism to therapeutics. |