Epithelial-specific ETS-1 (ESE1/ELF3) regulates apoptosis of intestinal epithelial cells in ulcerative colitis via accelerating NF-κB activation.

scientific article published on June 2015

Epithelial-specific ETS-1 (ESE1/ELF3) regulates apoptosis of intestinal epithelial cells in ulcerative colitis via accelerating NF-κB activation. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1049661810
P356DOI10.1007/S12026-015-8651-3
P698PubMed publication ID25926267

P50authorRunzhou NiQ57010305
P2093author name stringLijun Yan
Liang Wang
Liren Li
Dongmei Zhang
Qiyun Tang
Xianjing Miao
Xiaobing Miao
Xiaodan Gu
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Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epitheliumQ38018004
Understanding the role of ETS-mediated gene regulation in complex biological processesQ38122802
Predictors of response to anti-tumor necrosis factor therapy in ulcerative colitisQ38240881
Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1.Q38354653
Interplay between proximal and distal promoter elements is required for squamous differentiation marker induction in the bronchial epithelium: role for ESE-1, Sp1, and AP-1 proteinsQ38355456
ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-κB and drives prostate cancer progressionQ39149787
Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammationQ39982882
Kinase suppressor of Ras determines survival of intestinal epithelial cells exposed to tumor necrosis factor.Q40762019
The Counter-Regulatory Effects of ESE-1 During Angiotensin II-Mediated Vascular Inflammation and RemodelingQ42475414
Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatmentQ43004927
A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in miceQ44753508
ESX: a structurally unique Ets overexpressed early during human breast tumorigenesisQ44836253
IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosisQ46607308
Khz (fusion product of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis in human colon carcinoma HCT116 cells, accompanied by an increase in reactive oxygen species, activation of caspase 3, and increased intracellular Ca²⁺.Q46800904
A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancerQ48041882
Increase in colorectal epithelial apoptotic cells in patients with ulcerative colitis ultimately requiring surgery.Q52546687
Experimental study on the molecular mechanism of anthraquinone cathartics in inducing melanosis coli.Q54357890
Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiationQ73061193
ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kappa B to regulate the inducible nitric-oxide synthase geneQ73088280
Growth in epithelial cell proliferation and apoptosis correlates specifically to the inflammation activity of inflammatory bowel diseases: ulcerative colitis shows specific p53- and EGFR expression alterationsQ81476795
Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiationQ22253938
ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammationQ24304282
Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets familyQ24319000
Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86Q24336207
Immunopathology of inflammatory bowel diseaseQ27027636
Intestinal barrier function: molecular regulation and disease pathogenesisQ28250081
SCYL1BP1 modulates neurite outgrowth and regeneration by regulating the Mdm2/p53 pathwayQ28572542
Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epitheliumQ28594344
TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosisQ30310991
A novel ets-related transcription factor, ERT/ESX/ESE-1, regulates expression of the transforming growth factor-beta type II receptorQ32161090
Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathwaysQ33808592
CXCR4 antagonist AMD3100 modulates claudin expression and intestinal barrier function in experimental colitisQ34071898
Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's diseaseQ34145454
Tumor necrosis factor-α-induced colitis increases NADPH oxidase 1 expression, oxidative stress, and neutrophil recruitment in the colon: preventive effect of apocyninQ34207197
The immunological and genetic basis of inflammatory bowel diseaseQ34216426
The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanismQ34347627
Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel diseaseQ34412235
PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice.Q34876574
Anti-cancer effect and apoptosis induction of cordycepin through DR3 pathway in the human colonic cancer cell HT-29.Q34939587
An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factorsQ35004774
The gut microbiota and inflammatory bowel diseaseQ35446516
Innate immunity and apoptosis in IBD.Q35787661
Immune markers and differential signaling networks in ulcerative colitis and Crohn's diseaseQ36125752
ETS transcription factors and their emerging roles in human cancerQ36280928
Antibodies to interleukin 12 abrogate established experimental colitis in miceQ36365464
Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposedQ36421519
Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammationQ36455179
Regulation of apoptosis during homeostasis and disease in the intestinal epitheliumQ36467014
The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.Q36552070
NF-κB pathway in colitis-associated cancersQ36795773
ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cellsQ37098082
The genetics and immunopathogenesis of inflammatory bowel diseaseQ37171800
Carcinogenesis in IBD: potential targets for the prevention of colorectal cancerQ37464715
P433issue2
P921main subjectulcerative colitisQ1477
NF-κBQ411114
P304page(s)198-212
P577publication date2015-06-01
P1433published inImmunologic ResearchQ15754981
P1476titleEpithelial-specific ETS-1 (ESE1/ELF3) regulates apoptosis of intestinal epithelial cells in ulcerative colitis via accelerating NF-κB activation
P478volume62

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cites work (P2860)
Q37706684Down-regulation of toll-like receptor 4 alleviates intestinal ischemia reperfusion injury and acute lung injury in mice
Q64076377ESE1 expression correlates with neuronal apoptosis in the hippocampus after cerebral ischemia/reperfusion injury
Q39650158ESE1 is Associated with Neuronal Apoptosis in Lipopolysaccharide Induced Neuroinflammation
Q91525435Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma
Q58738376FKBP11 protects intestinal epithelial cells against inflammation‑induced apoptosis via the JNK‑caspase pathway in Crohn's disease
Q38603810Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells.
Q92715415Jagged-1 attenuates LPS-induced apoptosis and ROS in rat intestinal epithelial cells
Q49278089The Antioxidant Procyanidin Reduces Reactive Oxygen Species Signaling in Macrophages and Ameliorates Experimental Colitis in Mice.
Q53092853The suppressor of cytokine signaling SOCS1 promotes apoptosis of intestinal epithelial cells via p53 signaling in Crohn's disease.

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