Purinergic Signalling in the Gut.

scientific article

Purinergic Signalling in the Gut. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/978-3-319-27592-5_10
P698PubMed publication ID27379638

P50authorGeoffrey BurnstockQ5534494
P2860cites workInvolvement of P2Y1 and P2Y11 purinoceptors in parasympathetic inhibition of colonic smooth muscleQ24301884
The physiological activity of adenine compounds with especial reference to their action upon the mammalian heartQ24540404
Purinergic signaling in the gastrointestinal tractQ24632986
Blockade of adenosine A2B receptors ameliorates murine colitisQ24650596
Purinergic signalling in the gastrointestinal tract and related organs in health and diseaseQ26861086
Molecular physiology of P2X receptorsQ28203477
Pharmacology of P2X channelsQ28237411
The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system.Q44236293
P2 receptors in the murine gastrointestinal tractQ44278093
The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide, is protective in two murine models of colitisQ44403155
Slow excitatory synaptic transmission mediated by P2Y1 receptors in the guinea-pig enteric nervous systemQ44478894
Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectumQ44642518
Serum adenosine deaminase activity as a predictor of disease severity in ulcerative colitisQ44644777
ATP participates in three excitatory postsynaptic potentials in the submucous plexus of the guinea pig ileum.Q44765828
Purinergic component of mechanosensory transduction is increased in a rat model of colitisQ45032136
The distribution of P2X5 purinergic receptors in the enteric nervous system of mouseQ45155074
Gastric ulcers evoke hyperexcitability and enhance P2X receptor function in rat gastric sensory neuronsQ45240129
Purinergic modulation of pacemaker Ca2+ activity in interstitial cells of CajalQ45253593
Expression of P2X6 receptors in the enteric nervous system of the rat gastrointestinal tractQ45285228
Estrogen altered visceromotor reflex and P2X(3) mRNA expression in a rat model of colitis.Q45921847
Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of postinfectious bowel diseaseQ46120452
Loss of purinergic vascular regulation in the colon during colitis is associated with upregulation of CD39.Q46202324
Oxidative stress disrupts purinergic neuromuscular transmission in the inflamed colonQ46252455
Colonic mucosal mediators from patients with irritable bowel syndrome excite enteric cholinergic motor neuronsQ46258357
Non-additive interaction between nicotinic cholinergic and P2X purine receptors in guinea-pig enteric neurons in cultureQ46316072
Purinergic fast excitatory postsynaptic potentials in myenteric neurons of guinea pig: Distribution and pharmacologyQ46337940
Cross-inhibitory interactions between GABAA and P2X channels in myenteric neuronesQ46478791
Functional interactions between nicotinic and P2X channels in short-term cultures of guinea-pig submucosal neuronsQ46479411
Properties of the inhibitory potential of smooth muscle as observed in the response to field stimulation of the guinea-pig taenia coliQ46486471
P2X2 receptors are essential for [Ca2+]i increases in response to ATP in cultured rat myenteric neuronsQ46499781
Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice.Q46537534
Descending inhibitory reflexes involve P2X receptor-mediated transmission from interneurons to motor neurons in guinea-pig ileumQ46620425
The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors.Q42953375
Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileumQ43130219
A novel calcium-sensitive potassium conductance is coupled to P2X3 subunit containing receptors in myenteric neurons of guinea pig ileumQ43146655
Pharmacological evidence for the existence of multiple P2 receptors in the circular muscle of guinea-pig colon.Q43179752
Purinergic neuromuscular transmission is selectively attenuated in ulcerated regions of inflamed guinea pig distal colonQ43197442
Purine-mediated signalling in pain and visceral perceptionQ43562396
Purinergic neuron-to-glia signaling in the enteric nervous systemQ43641718
ATP-gated ion channel P2X(3) is increased in human inflammatory bowel disease.Q43750395
The distribution of purine P2X(2) receptors in the guinea-pig enteric nervous systemQ44005474
Interstitial cells of Cajal and purinergic signallingQ44009923
The gaseous mediator, hydrogen sulphide, inhibits in vitro motor patterns in the human, rat and mouse colon and jejunumQ44016650
ATP as a putative sensory mediator: activation of intrinsic sensory neurons of the myenteric plexus via P2X receptors.Q44037028
Inhibitory interactions between 5-HT3 and P2X channels in submucosal neuronsQ44185439
The birth and postnatal development of purinergic signallingQ28277866
Smooth muscle does not have a common P2x receptor phenotype: expression, ontogeny and function of P2x1 receptors in mouse ileum, bladder and reproductive systemsQ28586158
P2X2 subunits contribute to fast synaptic excitation in myenteric neurons of the mouse small intestineQ28590535
Peristalsis is impaired in the small intestine of mice lacking the P2X3 subunitQ28591337
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel diseaseQ30437360
A2B adenosine receptor gene deletion attenuates murine colitisQ30438772
Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitisQ30441350
Dual purinergic synaptic transmission in the human enteric nervous systemQ33310253
Release of vasoactive substances from endothelial cells by shear stress and purinergic mechanosensory transductionQ33674255
Purinergic autocrine regulation of mechanosensitivity and serotonin release in a human EC model: ATP-gated P2X3 channels in EC are downregulated in ulcerative colitisQ33683423
Multiple mechanisms of fast excitatory synaptic transmission in the enteric nervous systemQ33951852
The enteric purinergic P2Y1 receptorQ33999025
Purinergic receptors in gastrointestinal inflammationQ34008598
Molecular mechanisms of cross-inhibition between nicotinic acetylcholine receptors and P2X receptors in myenteric neurons and HEK-293 cellsQ34026091
Effects of protein deprivation and re-feeding on P2X2 receptors in enteric neurons.Q34041398
Receptors and transmission in the brain-gut axis: potential for novel therapies. I. Receptors on visceral afferentsQ34211931
The liberation of adenosine triphosphate on antidromic stimulation of sensory nervesQ34245951
Do some nerve cells release more than one transmitter?Q34259493
Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors.Q34297567
Transmission to interneurons is via slow excitatory synaptic potentials mediated by P2Y(1) receptors during descending inhibition in guinea-pig ileumQ34574997
Inhibition of adenosine deaminase attenuates inflammation in experimental colitis.Q34654041
The Stimulatory Adenosine Receptor ADORA2B Regulates Serotonin (5-HT) Synthesis and Release in Oxygen-Depleted EC Cells in Inflammatory Bowel DiseaseQ34701850
Pharmacology of synaptic transmission in the enteric nervous systemQ35026089
Enteric P2X receptors as potential targets for drug treatment of the irritable bowel syndromeQ35047062
Impact of disrupting adenosine A3 receptors (A3−/−AR) on colonic motility or progression of colitis in the mouseQ35048408
Efferent-like roles of afferent neurons in the gut: Blood flow regulation and tissue protectionQ35187915
ATP and sensory transduction in the enteric nervous system.Q35204992
Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non-adrenergic inhibitory nerves in the gut.Q35226290
Intrinsic primary afferent neurons and nerve circuits within the intestineQ35737831
Enteric motor and interneuronal circuits controlling motilityQ35738916
Pharmacology and function of nicotinic acetylcholine and P2X receptors in the enteric nervous systemQ35738940
Gastrointestinal pain in functional bowel disorders: sensory neurons as novel drug targetsQ35753361
Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitisQ35874789
Cellular distribution and functions of P2 receptor subtypes in different systemsQ35952737
Differential expression of P2X-purinoceptor subtypes in circular and longitudinal muscle of canine colonQ46633376
P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivityQ46757612
Slow postsynaptic potentials in neurones of submucous plexus of guinea-pig caecum and their mimicry by noradrenaline and various peptidesQ46886570
Distribution of P2Y6 and P2Y12 receptor: their colocalization with calbindin, calretinin and nitric oxide synthase in the guinea pig enteric nervous systemQ46891041
A2a receptors mediate inhibitory effects of adenosine on colonic motility in the presence of experimental colitisQ46908088
Postnatal development of P2 receptors in the murine gastrointestinal tractQ46909592
Calcium responses in subserosal interstitial cells of the guinea-pig proximal colonQ46917479
ATP regulates synaptic transmission by pre- and postsynaptic mechanisms in guinea-pig myenteric neuronsQ46921566
Sympathetic vasoconstrictor regulation of mouse colonic submucosal arterioles is altered in experimental colitisQ48585326
Inhibitory neuromuscular transmission mediated by the P2Y1 purinergic receptor in guinea pig small intestineQ48618475
Projections and chemistry of Dogiel type II neurons in the mouse colon.Q49300330
P2X7 receptors contribute to the currents induced by ATP in guinea pig intestinal myenteric neurons.Q50436338
Purinergic neuromuscular transmission is absent in the colon of P2Y(1) knocked out miceQ50516161
A functional role for the 'fibroblast-like cells' in gastrointestinal smooth musclesQ50530820
ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysisQ50718849
P2Y6 Receptor Contributes to Neutrophil Recruitment to Inflamed Intestinal Mucosa by Increasing Cxc Chemokine Ligand 8 Expression in an AP-1-dependent Manner in Epithelial CellsQ51544408
Bursts of recurrent excitation in the activation of intrinsic sensory neurons of the intestineQ51608928
Adenosine 5'-triphosphate modulates membrane potassium conductance in guinea-pig myenteric neuronesQ51762766
The inhibitory innervation of the taenia of the guinea-pig caecumQ52759161
Variable impact of CD39 in experimental murine colitisQ53296335
[3H]adenosine triphosphate: release during stimulation of enteric nervesQ54045304
Analysis of the contractile responses of the ileal segment of the isolated blood-perfused small intestine of rats to adenosine triphosphate and related compoundsQ54567047
Mechanisms of alpha,beta-methylene atp-induced inhibition in rat ileal smooth muscle: involvement of intracellular Ca2+ stores in purinergic inhibition.Q54567650
Selective labeling and isolation of functional classes of interstitial cells of Cajal of human and murine small intestine.Q54584772
Purinergic and cholinergic neuro-neuronal transmission underlying reflexes activated by mucosal stimulation in the isolated guinea-pig ileumQ54989459
ATP-induced currents in submucous plexus neurons of the guinea pig small intestineQ57764760
On Inhibitory Fibres in the Vagus for the end of the OEsophagus and the StomachQ58789912
P2X7 Receptor-Dependent Intestinal Afferent Hypersensitivity in a Mouse Model of Postinfectious Irritable Bowel SyndromeQ63363269
Presynaptic inhibition by adenosine A1 receptors on guinea pig small intestinal myenteric neuronsQ70681107
Enteric glia exhibit P2U receptors that increase cytosolic calcium by a phospholipase C-dependent mechanismQ70979129
Changes in intracellular Ca2+ by activation of P2 receptors in submucosal neurons in short-term culturesQ73275958
A method for studying the effects of ions and drugs on the resting and action potentials in smooth muscle with external electrodesQ74822670
P2X2 and P2X3 purinoceptors in the rat enteric nervous systemQ75438108
Central and synaptic transmission in the nervous system; pharmacological aspectsQ77053120
P2X receptors in the rat duodenal villusQ77979101
INNERVATION OF THE GUINEA-PIG TAENIA COLI: ARE THERE INTRINSIC INHIBITORY NERVES WHICH ARE DISTINCT FROM SYMPATHETIC NERVES?Q78522456
An analysis of the responses of the isolated stomach to electrical stimulation and to drugsQ79460037
Local effect of adenosine 5'-triphosphate on indomethacin-induced permeability changes in the human small intestineQ79777112
The stimulating action of phosphate compounds on the perfused superior cervical ganglion of the catQ80317311
The response of smooth muscle to stimulation of the vagus nerveQ80326787
Development of nerves expressing P2X3 receptors in the myenteric plexus of rat stomachQ80350444
Distribution of P2Y2 receptors in the guinea pig enteric nervous system and its coexistence with P2X2 and P2X3 receptors, neuropeptide Y, nitric oxide synthase and calretininQ81149345
Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitisQ82231690
Region-specific distribution of the P2Y4 receptor in enteric glial cells and interstitial cells of Cajal within the guinea-pig gastrointestinal tractQ83158372
Adenosine deaminase activity in patients with Crohn's disease: distinction between active and nonactive diseaseQ84143461
P2Y(2) receptor expression is regulated by C/EBPβ during inflammation in intestinal epithelial cellsQ84481042
Adenosine 5'-triphosphate and its relationship with other mediators that activate pelvic nerve afferent neurons in the rat colorectum.Q36182806
Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestineQ36516823
Adenosine and gastrointestinal inflammation.Q36575938
Purine and pyrimidine receptorsQ36765468
Physiology and pathophysiology of purinergic neurotransmissionQ36788894
Purinergic mechanisms in the control of gastrointestinal motilityQ36793756
Purinergic receptors and gastrointestinal secretomotor functionQ36793761
The A3 adenosine receptor: an enigmatic player in cell biologyQ37009175
Painful purinergic receptorsQ37016540
Interstitial cells of Cajal in diabetic gastroenteropathyQ37049428
Purinergic receptors and synaptic transmission in enteric neurons.Q37119870
New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.Q37229766
Purinergic receptors as future targets for treatment of functional GI disordersQ37249236
Adenosine: an immune modulator of inflammatory bowel diseasesQ37362853
Purinergic mechanosensory transduction and visceral painQ37463074
Adenosine in the Inflamed Gut: A Janus Faced CompoundQ37886017
Cardiovascular purinoceptorsQ37937544
Characterizing the presence and sensitivity of the P2X7 receptor in different compartments of the gut.Q38003084
Roles of Substance P and ATP in the Subepithelial Fibroblasts of Rat Intestinal VilliQ38117813
Chemical coding of neurons and plurichemical transmissionQ38351782
Extracellular ATP induces cell death in human intestinal epithelial cellsQ39285078
Neuroligands evoke calcium signaling in cultured myenteric neuronsQ39375732
Development of Polar Adenosine A2A Receptor Agonists for Inflammatory Bowel Disease: Synergism with A2B AntagonistsQ39514425
Adenosine A(2A) agonist and A(2B) antagonist mediate an inhibition of inflammation-induced contractile disturbance of a rat gastrointestinal preparationQ39600697
Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migrationQ39735000
Intestinal inflammation increases the expression of the P2Y6 receptor on epithelial cells and the release of CXC chemokine ligand 8 by UDP.Q40016360
The P2Y purinergic receptor expressed by enteric neurones in guinea-pig intestineQ40301169
TNF-alpha upregulates adenosine 2b (A2b) receptor expression and signaling in intestinal epithelial cells: a basis for A2bR overexpression in colitisQ40344775
Signalling via ATP in the nervous systemQ40397169
Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotidesQ40768521
Functional evidence that ATP or a related purine is an inhibitory NANC neurotransmitter in the mouse jejunum: study on the identity of P2X and P2Y purinoceptors involved.Q41817576
Discovery of purinergic signalling, the initial resistance and current explosion of interestQ41954765
Characterization of the P2Y-purinoceptor involved in the ATP-induced rise in cytosolic Ca2+ concentration in rat ileal myocytesQ42124027
Enteric glia are targets of the sympathetic innervation of the myenteric plexus in the guinea pig distal colon.Q42170689
Vasoconstriction of guinea-pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATPQ42177812
Evidence for the presence of P1-purinoceptors on cholinergic nerve terminals in the guinea-pig ileumQ42245504
Contractile effects of uridine 5'-triphosphate in the rat duodenumQ42371133
P2X purinoceptor-induced sensitization of ferret vagal mechanoreceptors in oesophageal inflammationQ42484397
P2x-purinoceptors of myenteric neurones from the guinea-pig ileum and their unusual pharmacological propertiesQ42581725
P2X purinoceptors in cultured myenteric neurons of guinea-pig small intestineQ42644668
Responses of the longitudinal muscle and the muscularis mucosae of the rat duodenum to adenine and uracil nucleotidesQ42705705
Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.Q42877119
P407language of work or nameEnglishQ1860
P304page(s)91-112
P577publication date2016-01-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inAdvances in Experimental Medicine and BiologyQ4686385
P1476titlePurinergic Signalling in the Gut.
P478volume891

Reverse relations

cites work (P2860)
Q90411947Electroacupuncture Inhibits the Activity of Astrocytes in Spinal Cord in Rats with Visceral Hypersensitivity by Inhibiting P2Y1 Receptor-Mediated MAPK/ERK Signaling Pathway
Q50202418The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?
Q91701115The first digestive movements in the embryo are mediated by mechanosensitive smooth muscle calcium waves

Search more.