Targeting mitochondria in cancer cells using gold nanoparticle-enhanced radiotherapy: a Monte Carlo study

scientific article

Targeting mitochondria in cancer cells using gold nanoparticle-enhanced radiotherapy: a Monte Carlo study is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1118/1.4906192
P698PubMed publication ID25652523

P2093author name stringCharles Kirkby
Esmaeel Ghasroddashti
P2860cites workThe mitochondrial inner membrane protein mitofilin controls cristae morphologyQ24556571
The dosimetric feasibility of gold nanoparticle-aided radiation therapy (GNRT) via brachytherapy using low-energy gamma-/x-ray sourcesQ24632315
Mitochondria, oxidative stress and cell deathQ29618996
Spektr: a computational tool for x-ray spectral analysis and imaging system optimizationQ31135007
Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: a microscopic overviewQ33226381
Estimation of microscopic dose enhancement factor around gold nanoparticles by Monte Carlo calculationsQ33689742
Cell-specific radiosensitization by gold nanoparticles at megavoltage radiation energiesQ34462887
Contact sites between the outer and inner membrane of mitochondria-role in protein transportQ34793178
Gold nanoparticle imaging and radiotherapy of brain tumors in miceQ36853281
Theranostic gold nanoparticles modified for durable systemic circulation effectively and safely enhance the radiation therapy of human sarcoma cells and tumorsQ37474389
Tumor microenvironment and nanotherapeuticsQ37632757
Ionizing radiation-induced metabolic oxidative stress and prolonged cell injuryQ37693239
Intracellular uptake, transport, and processing of gold nanostructures.Q37798554
Effects of ionizing radiation on mitochondriaQ38124680
Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticlesQ39119168
A Monte Carlo-based model of gold nanoparticle radiosensitization accounting for increased radiobiological effectivenessQ39164576
Dependence of Monte Carlo microdosimetric computations on the simulation geometry of gold nanoparticles.Q39324477
Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles.Q39330773
Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint.Q39349358
Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapyQ39472564
Thio-glucose bound gold nanoparticles enhance radio-cytotoxic targeting of ovarian cancer.Q39528503
Selective targeting of gold nanorods at the mitochondria of cancer cells: implications for cancer therapyQ39615451
Evaluation of cytotoxicity and radiation enhancement using 1.9 nm gold particles: potential application for cancer therapyQ39684409
Enhancement of cell radiation sensitivity by pegylated gold nanoparticles.Q39749727
Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycleQ39808184
Interaction of gold nanoparticles with mitochondriaQ39867106
Enhancement of radiation cytotoxicity in breast-cancer cells by localized attachment of gold nanoparticlesQ39949337
Enhancement of radiation effects by gold nanoparticles for superficial radiation therapy.Q39975675
DNA damage enhancement from gold nanoparticles for clinical MV photon beamsQ42011166
Mitochondrial modulation of apoptosis induced by low-dose radiation in mouse testicular cellsQ46973106
Implications on clinical scenario of gold nanoparticle radiosensitization in regards to photon energy, nanoparticle size, concentration and locationQ47367623
Monte Carlo calculation of nine megavoltage photon beam spectra using the BEAM code.Q52043405
Radiotherapy in the presence of contrast agents: a general figure of merit and its application to gold nanoparticlesQ57696255
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectnanoparticleQ61231
Adaptive radiation therapyQ180507
P304page(s)1119-1128
P577publication date2015-02-01
P1433published inMedical PhysicsQ15764251
P1476titleTargeting mitochondria in cancer cells using gold nanoparticle-enhanced radiotherapy: a Monte Carlo study
P478volume42

Reverse relations

cites work (P2860)
Q41468679Dose enhancement effects to the nucleus and mitochondria from gold nanoparticles in the cytosol
Q47849946Dosimetric consequences of gold nanoparticle clustering during photon irradiation.
Q60492360Geometrical structures for radiation biology research as implemented in the TOPAS-nBio toolkit
Q39078026Heterogeneous multiscale Monte Carlo simulations for gold nanoparticle radiosensitization
Q92866077In vivo gadolinium nanoparticle quantification with SPECT/CT
Q38661115Nanoscale radiation transport and clinical beam modeling for gold nanoparticle dose enhanced radiotherapy (GNPT) using X-rays
Q36094116Technical Note: spektr 3.0-A computational tool for x-ray spectrum modeling and analysis

Search more.