| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Hans-Joachim Anders | Q46256091 |
| P2093 | author name string | Hans-Joachim Anders | |
| P2860 | cites work | Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection | Q22251080 |
| Cloning and expression of murine interleukin-1 cDNA in Escherichia coli | Q24300988 | ||
| Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes | Q24339219 | ||
| Nucleotide sequence of human monocyte interleukin 1 precursor cDNA | Q24605740 | ||
| The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation | Q24628062 | ||
| Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization | Q24631966 | ||
| Keratinocyte expression of the type 2 interleukin 1 receptor mediates local and specific inhibition of interleukin 1-mediated inflammation | Q24673428 | ||
| Converging roles of caspases in inflammasome activation, cell death and innate immunity | Q26776532 | ||
| Horizon 2020 in Diabetic Kidney Disease: The Clinical Trial Pipeline for Add-On Therapies on Top of Renin Angiotensin System Blockade | Q26799443 | ||
| Gout-associated uric acid crystals activate the NALP3 inflammasome | Q28131797 | ||
| Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice. | Q46582632 | ||
| TLR4 and NALP3 inflammasome in the development of endothelial dysfunction in uraemia. | Q46800130 | ||
| Glomerular disease: limiting autoimmune tissue injury: ROS and the inflammasome | Q46847412 | ||
| ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction | Q46922399 | ||
| A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion | Q47096387 | ||
| Histones trigger sterile inflammation by activating the NLRP3 inflammasome | Q47733636 | ||
| NOD-like and Toll-like receptors or inflammasomes contribute to kidney disease in a canonical and a non-canonical manner | Q47889486 | ||
| The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation. | Q48030329 | ||
| Role of IL-1 in renal ischemic reperfusion injury. | Q48485184 | ||
| Different patterns of interleukin-1alpha and interleukin-1beta expression in organs of normal young and old mice. | Q48630118 | ||
| Safety and pharmacokinetics of subcutaneously administered rilonacept in patients with well-controlled end-stage renal disease (ESRD). | Q51763955 | ||
| Interleukin-18 affects local cytokine expression but does not impact on the development of kidney allograft rejection. | Q53011861 | ||
| Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1. | Q53178008 | ||
| Soluble monosodium urate, but not its crystal, induces toll like receptor 4-dependent immune activation in renal mesangial cells. | Q53531294 | ||
| Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney. | Q53562266 | ||
| NLRP3 and ASC suppress lupus-like autoimmunity by driving the immunosuppressive effects of TGF-β receptor signalling. | Q54194314 | ||
| Regulation of TLR2 and NLRP3 in primary murine renal tubular epithelial cells. | Q54211003 | ||
| Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation. | Q54420633 | ||
| Renal involvement in secondary amyloidosis of Muckle-Wells syndrome: marked improvement of renal function and reduction of proteinuria after therapy with human anti-interleukin-1β monoclonal antibody canakinumab | Q58326117 | ||
| Interleukin-1-dependent sequential chemokine expression and inflammatory cell infiltration in ischemia-reperfusion injury | Q62735783 | ||
| Genetically modified bone marrow-derived vehicle cells site specifically deliver an anti-inflammatory cytokine to inflamed interstitium of obstructive nephropathy | Q73311951 | ||
| Inhibition of TNF-alpha, induced cytokine and adhesion molecule. Expression in glomerular cells in vitro and in vivo by transcription factor decoy for NFkappaB | Q73843645 | ||
| Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice | Q81256287 | ||
| Interleukin-1beta and receptor antagonist (IL-1Ra) gene polymorphisms and the prediction of the risk of end-stage renal disease | Q83966442 | ||
| Signaling through the interleukin-18 receptor α attenuates inflammation in cisplatin-induced acute kidney injury | Q84311451 | ||
| Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS) | Q85063666 | ||
| Simiao pill ameliorates renal glomerular injury via increasing Sirt1 expression and suppressing NF-κB/NLRP3 inflammasome activation in high fructose-fed rats | Q85481554 | ||
| Improved renal function in diabetic patients with acute gout treated with anakinra | Q85498193 | ||
| A pan caspase inhibitor decreases caspase-1, IL-1α and IL-1β, and protects against necrosis of cisplatin-treated freshly isolated proximal tubules | Q85772691 | ||
| Inflammasome-independent NLRP3 augments TGF-β signaling in kidney epithelium | Q85778659 | ||
| The NLRP3/ASC inflammasome promotes T-cell-dependent immune complex glomerulonephritis by canonical and noncanonical mechanisms | Q87828261 | ||
| Interleukin-1 and its relevance in patients treated with hemodialysis. | Q39637981 | ||
| Neutrophil-independent mechanisms of caspase-1- and IL-18-mediated ischemic acute tubular necrosis in mice | Q39737271 | ||
| Predominant Tubular Interleukin-18 Expression in Polyomavirus-Associated Nephropathy | Q40007734 | ||
| Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy | Q40035222 | ||
| Anti-IL-1 treatment in familial Mediterranean fever and related amyloidosis | Q40191340 | ||
| Dramatic beneficial effect of interleukin-1 inhibitor treatment in patients with familial Mediterranean fever complicated with amyloidosis and renal failure | Q40311616 | ||
| Successful treatment of familial Mediterranean fever with Anakinra and outcome after renal transplantation | Q40404007 | ||
| Successful treatment of renal amyloidosis due to familial cold autoinflammatory syndrome using an interleukin 1 receptor antagonist. | Q40456308 | ||
| Synergistic effect of IL-1alpha, IFN-gamma, and TNF-alpha on RANTES production by human renal tubular epithelial cells in vitro. | Q41053949 | ||
| Cytokines in human renal interstitial fibrosis. II. Intrinsic interleukin (IL)-1 synthesis and IL-1-dependent production of IL-6 and IL-8 by cultured kidney fibroblasts | Q41365080 | ||
| Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor. | Q41675311 | ||
| Role of IL-1α in cisplatin-induced acute renal failure in mice | Q42025525 | ||
| The fire within: pyroptosis in the kidney | Q43587050 | ||
| Noncanonical inflammasome activation by intracellular LPS independent of TLR4. | Q44450840 | ||
| Contributions of IL-1beta and IL-1alpha to crescentic glomerulonephritis in mice | Q44807517 | ||
| Molecular mechanisms of crystal-related kidney inflammation and injury. Implications for cholesterol embolism, crystalline nephropathies and kidney stone disease | Q44855203 | ||
| Interleukin-1 gene cluster polymorphisms predict risk of ESRD. | Q44937748 | ||
| Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis | Q45166196 | ||
| The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response | Q28242527 | ||
| The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation | Q28242537 | ||
| Cryopyrin activates the inflammasome in response to toxins and ATP | Q28291313 | ||
| The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease | Q28395210 | ||
| Thioredoxin-interacting protein links oxidative stress to inflammasome activation | Q29614471 | ||
| Inflammasomes in health and disease | Q29616356 | ||
| Do children need fairytales? | Q30358838 | ||
| Alarmins: awaiting a clinical response | Q30523797 | ||
| Urine interleukin-18 in prediction of acute kidney injury: a systemic review and meta-analysis | Q31162581 | ||
| Inflammasome activation by cystine crystals: implications for the pathogenesis of cystinosis | Q33660585 | ||
| Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis | Q34020795 | ||
| The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. | Q34023691 | ||
| Inflammatory caspases are innate immune receptors for intracellular LPS. | Q34041730 | ||
| Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1. | Q34064677 | ||
| Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia | Q34245112 | ||
| Uromodulin triggers IL-1β-dependent innate immunity via the NLRP3 inflammasome | Q34300979 | ||
| The interleukin-1 family: back to the future | Q34391415 | ||
| Activating Nrf-2 signaling depresses unilateral ureteral obstruction-evoked mitochondrial stress-related autophagy, apoptosis and pyroptosis in kidney | Q34448170 | ||
| The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. | Q34455462 | ||
| Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet | Q34459280 | ||
| An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury | Q34485850 | ||
| IL-1β receptor antagonist reduces inflammation in hemodialysis patients | Q34695324 | ||
| Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy | Q34836376 | ||
| Phagocyte NADPH oxidase restrains the inflammasome in ANCA-induced GN | Q35027263 | ||
| Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor I to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis | Q35098385 | ||
| The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease | Q35155012 | ||
| A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. | Q35350543 | ||
| Regulation of inflammasome activation | Q35456425 | ||
| Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation | Q35551778 | ||
| Primary and secondary hyperoxaluria: Understanding the enigma | Q35567868 | ||
| Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury | Q35686207 | ||
| Neutrophil serine proteases promote IL-1β generation and injury in necrotizing crescentic glomerulonephritis | Q35804151 | ||
| Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation | Q35859536 | ||
| Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling | Q36041225 | ||
| Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes | Q36266939 | ||
| Identification of a specific interleukin 1 inhibitor in the urine of febrile patients | Q36348429 | ||
| Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion | Q36497205 | ||
| Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice. | Q36546979 | ||
| Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity | Q36745305 | ||
| Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases | Q36816872 | ||
| Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion | Q36894381 | ||
| Meprin A and meprin alpha generate biologically functional IL-1beta from pro-IL-1beta | Q36985463 | ||
| The Interleukin-1α Precursor is Biologically Active and is Likely a Key Alarmin in the IL-1 Family of Cytokines | Q37326965 | ||
| NLRP3 inflammasome knockout mice are protected against ischemic but not cisplatin-induced acute kidney injury | Q37422647 | ||
| Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors | Q37433274 | ||
| Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome | Q37453447 | ||
| Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction | Q37484299 | ||
| Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia | Q37622159 | ||
| The inflammasomes in kidney disease | Q37874866 | ||
| Emerging therapies for gout | Q38057761 | ||
| Regulation of interleukin 1α secretion by inflammasomes | Q38068689 | ||
| Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis. | Q38136506 | ||
| Interleukin-18, more than a Th1 cytokine | Q38166154 | ||
| Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis | Q38206875 | ||
| Pattern recognition receptors and the inflammasome in kidney disease. | Q38217071 | ||
| Inflammasome-independent regulation of IL-1-family cytokines | Q38286016 | ||
| Administration of interleukin-1 receptor antagonist ameliorates renal ischemia-reperfusion injury | Q38292408 | ||
| Partial response to anakinra in life-threatening Henoch-Schönlein purpura: case report | Q38356731 | ||
| Hyperuricemia-induced NLRP3 activation of macrophages contributes to the progression of diabetic nephropathy | Q38428834 | ||
| Therapeutics targeting persistent inflammation in chronic kidney disease | Q38546860 | ||
| Necroinflammation in Kidney Disease | Q38579499 | ||
| Macrophage cell death in microbial infections. | Q38718913 | ||
| Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. | Q38835006 | ||
| Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death | Q38835009 | ||
| Ischemia-reperfusion induces renal tubule pyroptosis via the CHOP-caspase-11 pathway | Q39077576 | ||
| ASC speck formation as a readout for inflammasome activation | Q39126034 | ||
| Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions | Q39247885 | ||
| Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury | Q39413610 | ||
| P433 | issue | 9 | |
| P921 | main subject | inflammasome complex | Q412405 |
| P304 | page(s) | 2564-2575 | |
| P577 | publication date | 2016-08-11 | |
| P1433 | published in | Journal of the American Society of Nephrology | Q17123893 |
| P1476 | title | Of Inflammasomes and Alarmins: IL-1β and IL-1α in Kidney Disease | |
| P478 | volume | 27 |
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| Q52589075 | CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease. |
| Q39144172 | Crystal nephropathies: mechanisms of crystal-induced kidney injury. |
| Q92017698 | Current understanding of the administration of mesenchymal stem cells in acute kidney injury to chronic kidney disease transition: a review with a focus on preclinical models |
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| Q52676433 | Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation. |
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