Dianthin-EGF is an effective tumor targeted toxin in combination with saponins in a xenograft model for colon carcinoma

scientific article

Dianthin-EGF is an effective tumor targeted toxin in combination with saponins in a xenograft model for colon carcinoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2217/FON.14.164
P698PubMed publication ID25471031

P50authorAlexander WengQ47101532
P2093author name stringMayank Thakur
Hendrik Fuchs
Horst Dürkop
Winfried Brenner
Matthias F Melzig
Mathias Lukas
Benedicta von Mallinckrodt
Nicola Beindorff
Roger Gilabert-Oriol
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Targeted tumor therapy by epidermal growth factor appended toxin and purified saponin: an evaluation of toxicity and therapeutic potential in syngeneic tumor bearing mice.Q39214329
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The toxin component of targeted anti-tumor toxins determines their efficacy increase by saponins.Q39656007
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A cleavable molecular adapter reduces side effects and concomitantly enhances efficacy in tumor treatment by targeted toxins in miceQ40185880
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A phase I trial of humanized monoclonal antibody A33 in patients with colorectal carcinoma: biodistribution, pharmacokinetics, and quantitative tumor uptakeQ40407709
Ribosome-inactivating proteins depurinate poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase and have transforming activity for 3T3 fibroblastsQ40664427
Sex Hormones and Colorectal Cancer: What Have We Learned So Far?Q42338932
Dianthins, ribosome-damaging proteins with anti-viral properties from Dianthus caryophyllus L. (carnation).Q45819212
Cancer and Leukemia Group B/Southwest Oncology Group trial 80405: a phase III trial of chemotherapy and biologics for patients with untreated advanced colorectal adenocarcinoma.Q45937932
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Real time monitoring of the cell viability during treatment with tumor-targeted toxins and saponins using impedance measurement.Q54517629
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectxenograftQ64148587
P304page(s)2161-2175
P577publication date2014-11-01
P1433published inFuture OncologyQ2781597
P1476titleDianthin-EGF is an effective tumor targeted toxin in combination with saponins in a xenograft model for colon carcinoma
P478volume10

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cites work (P2860)
Q26744722Augmenting the Efficacy of Immunotoxins and Other Targeted Protein Toxins by Endosomal Escape Enhancers
Q90722185Dianthin and Its Potential in Targeted Tumor Therapies
Q38703584Dianthin-30 or gelonin versus monomethyl auristatin E, each configured with an anti-calcitonin receptor antibody, are differentially potent in vitro in high-grade glioma cell lines derived from glioblastoma
Q50985144Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies.
Q41918293Plant Ribosome-Inactivating Proteins: Progesses, Challenges and Biotechnological Applications (and a Few Digressions).
Q38899428Recent progress in protein-protein interaction study for EGFR-targeted therapeutics
Q28072394Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins
Q47101471Targeted dianthin is a powerful toxin to treat pancreatic carcinoma when applied in combination with the glycosylated triterpene SO1861.

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