Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats.

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Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1004745834
P356DOI10.1186/1742-4690-10-47
P932PMC publication ID3651266
P698PubMed publication ID23622267
P5875ResearchGate publication ID236457527

P50authorK H KokQ73039649
P2093author name stringDong-Yan Jin
Yick-Pang Ching
Ching-Ping Chan
Hei-Man Vincent Tang
Yeung-Tung Siu
P2860cites workThe HTLV-1 Tax interactomeQ21093224
Host-pathogen interactome mapping for HTLV-1 and -2 retrovirusesQ21245042
MIP-T3 is a negative regulator of innate type I IFN responseQ24297023
TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeatsQ24548961
Specific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complexQ24798610
The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinomaQ24805822
Functional inactivation of a transcriptional corepressor by a signaling kinaseQ28188394
Protein profile of tax-associated complexesQ28207756
P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation.Q40144597
The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity.Q40227600
Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytesQ40318850
Acetylation of the adenovirus-transforming protein E1A determines nuclear localization by disrupting association with importin-alphaQ40713284
Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.Q40884279
Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoproteinQ44199158
Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in JapanQ45376179
Human T-cell leukemia virus oncoprotein tax represses nuclear receptor-dependent transcription by targeting coactivator TAX1BP1.Q45407499
X-I and X-II open reading frames of HTLV-I are not required for virus replication or for immortalization of primary T-cells in vitroQ45759936
A mechanism of COOH-terminal binding protein-mediated repressionQ46778171
Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaquesQ46878044
Coiled-coil motif as a structural basis for the interaction of HTLV type 1 Tax with cellular cofactors.Q55239893
Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.Q55240568
The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral responseQ83894699
p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cellsQ28216558
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1Q28219213
Nuclear localization and chromatin targets of p21-activated kinase 1Q28238246
Hepatitis B virus X protein confers resistance of hepatoma cells to anoikis by up-regulating and activating p21-activated kinase 1Q28263950
Molecular pathways: targeting p21-activated kinase 1 signaling in cancer--opportunities, challenges, and limitationsQ28266864
An emerging role for p21-activated kinases (Paks) in viral infectionsQ28270326
PAK3 mutation in nonsyndromic X-linked mental retardationQ28281729
CREB--a real culprit in oncogenesisQ28306040
Overexpression of a novel activator of PAK4, the CDK5 kinase-associated protein CDK5RAP3, promotes hepatocellular carcinoma metastasisQ28306804
Scaffolding function of PAK in the PDK1-Akt pathwayQ28570522
COT drives resistance to RAF inhibition through MAP kinase pathway reactivationQ29615032
Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulationQ30176025
Activation of TORC1 transcriptional coactivator through MEKK1-induced phosphorylationQ30440587
"UnPAKing" human immunodeficiency virus (HIV) replication: using small interfering RNA screening to identify novel cofactors and elucidate the role of group I PAKs in HIV infectionQ33229419
Phosphorylation of the human T-cell leukemia virus type 1 transactivator tax on adjacent serine residues is critical for tax activationQ33639780
A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fosQ33771493
The HTLV-1 tax protein cooperates with phosphorylated CREB, TORC2 and p300 to activate CRE-dependent cyclin D1 transcriptionQ33778149
Epidemiology, treatment, and prevention of human T-cell leukemia virus type 1-associated diseasesQ33983161
CREB and the CRTC co-activators: sensors for hormonal and metabolic signalsQ34166530
Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3.Q34355955
Molecular mechanisms of cellular transformation by HTLV-1 Tax.Q34450092
p21-Activated kinase 3 (PAK3) protein regulates synaptic transmission through its interaction with the Nck2/Grb4 protein adaptorQ35562644
Definition of a minimal activation domain in human T-cell leukemia virus type I TaxQ35835095
Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeatQ35873237
Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapyQ36147455
Transcriptional and post-transcriptional gene regulation of HTLV-1.Q36254862
The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.Q36483412
Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteinsQ36687133
LKB1 tumor suppressor and salt-inducible kinases negatively regulate human T-cell leukemia virus type 1 transcription.Q36808614
A tale of two PaksQ37058519
PAK signaling in oncogenesis.Q37494233
Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesisQ37995691
REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1.Q38318845
Involvement of TORC2, a CREB co-activator, in the in vivo-specific transcriptional control of HTLV-1.Q39815291
P921main subjectleukemiaQ29496
Human T-lymphotropic virus 1Q1280388
T-cell leukemiaQ7667895
P304page(s)47
P577publication date2013-04-26
P1433published inRetrovirologyQ15793508
P1476titleGroup I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats
P478volume10

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cites work (P2860)
Q41930624A mutation in PAK3 with a dual molecular effect deregulates the RAS/MAPK pathway and drives an X-linked syndromic phenotype.
Q21131117Highlights on distinctive structural and functional properties of HTLV Tax proteins
Q45325985Human T-Cell Leukemia Virus Type 1 Infection and Adult T-Cell Leukemia.
Q37713995Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response.
Q38949360Requirement of CRTC1 coactivator for hepatitis B virus transcription
Q38201237Rho'ing in and out of cells: viral interactions with Rho GTPase signaling
Q41170140SIRT1 Suppresses Human T-Cell Leukemia Virus Type 1 Transcription
Q38798967Suppression of Type I Interferon Production by Human T-Cell Leukemia Virus Type 1 Oncoprotein Tax through Inhibition of IRF3 Phosphorylation.

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