A novel long non-coding RNA ENST00000480739 suppresses tumour cell invasion by regulating OS-9 and HIF-1α in pancreatic ductal adenocarcinoma.

scientific article published on 14 October 2014

A novel long non-coding RNA ENST00000480739 suppresses tumour cell invasion by regulating OS-9 and HIF-1α in pancreatic ductal adenocarcinoma. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1045152523
P356DOI10.1038/BJC.2014.520
P932PMC publication ID4260035
P698PubMed publication ID25314054
P5875ResearchGate publication ID266944478

P50authorYong-Wei SunQ85220161
P2093author name stringW Liu
H Cao
J Li
Y-F Chen
J-Y Yang
J Hong
T Yan
J-F Zhang
R Hua
X-L Fu
D-J Liu
Y-M Huo
P2860cites workOS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alphaQ24295172
Core signaling pathways in human pancreatic cancers revealed by global genomic analysesQ24606006
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisQ24607308
The Long Noncoding RNA, Jpx, Is a Molecular Switch for X Chromosome InactivationQ24633255
The emergence of lncRNAs in cancer biologyQ27024237
DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.Q27851466
Targeting HIF-1 for cancer therapyQ27860504
Cancer statistics, 2012Q27860574
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammalsQ28131802
Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasionQ28142815
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 responseQ28592069
Cancer statistics, 2009Q29547625
Long noncoding RNAs with enhancer-like function in human cellsQ29614328
Evolution and functions of long noncoding RNAsQ29614331
Long noncoding RNAs: functional surprises from the RNA worldQ29615826
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancerQ29620125
Phenotypic characterization of endometrial stromal sarcoma of the uterusQ34488858
A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomasQ34552640
Genetics and biology of pancreatic ductal adenocarcinoma.Q34567515
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promotersQ34629890
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.Q34733220
The functional role of long non-coding RNA in human carcinomasQ34995156
A combined proteomics and metabolomics profiling of gastric cardia cancer reveals characteristic dysregulations in glucose metabolismQ35006537
PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regionsQ35051859
HIF-1α effects on angiogenic potential in human small cell lung carcinomaQ35217879
RETRACTED ARTICLE: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungsQ35571699
Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancerQ35576601
Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinomaQ35741707
Genome-wide screening for prognosis-predicting genes in early-stage non-small-cell lung cancerQ35955489
Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcriptsQ37197850
Advances in the treatment of pancreatic cancer: limitations of surgery and evaluation of new therapeutic strategiesQ37495626
No-nonsense functions for long noncoding RNAsQ37865710
Genetically engineered mouse models of pancreatic cancer: unravelling tumour biology and progressing translational oncology.Q37923241
Long noncoding RNA involvement in cancerQ38063049
Long noncoding RNA associated with microvascular invasion in hepatocellular carcinoma promotes angiogenesis and serves as a predictor for hepatocellular carcinoma patients' poor recurrence-free survival after hepatectomyQ39329786
Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivoQ39437873
Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1α-dependent manner in pancreatic cancer cells.Q39502908
Mutant p53 drives invasion by promoting integrin recyclingQ39753731
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activityQ40136909
Expression and regulatory role of GAIP-interacting protein GIPC in pancreatic adenocarcinomaQ40213160
Protein-bound polysaccharide PSK inhibits tumor invasiveness by down-regulation of TGF-beta1 and MMPsQ40793325
Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment in malignant gliomas.Q48255724
Cancer: Genomic evolution of metastasisQ59059835
Pancreatic tumors show high levels of hypoxiaQ73173983
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectadenocarcinomaQ356033
non-coding RNAQ427087
P304page(s)2131-2141
P577publication date2014-10-14
P1433published inBritish Journal of CancerQ326309
P1476titleA novel long non-coding RNA ENST00000480739 suppresses tumour cell invasion by regulating OS-9 and HIF-1α in pancreatic ductal adenocarcinoma
P478volume111

Reverse relations

cites work (P2860)
Q26801191Circulating RNAs as new biomarkers for detecting pancreatic cancer
Q38826625Downregulation of lncRNA-ATB correlates with clinical progression and unfavorable prognosis in pancreatic cancer
Q36546434Expression profile of long non-coding RNAs in pancreatic cancer and their clinical significance as biomarkers
Q64085985FOXO1-regulated lncRNA LINC01197 inhibits pancreatic adenocarcinoma cell proliferation by restraining Wnt/β-catenin signaling
Q49993926Genome-Wide Analysis Identified a Number of Dysregulated Long Noncoding RNA (lncRNA) in Human Pancreatic Ductal Adenocarcinoma
Q89412003Hypoxia-induced LncRNA-BX111 promotes metastasis and progression of pancreatic cancer through regulating ZEB1 transcription
Q36905828Hypoxia-induced lncRNA-NUTF2P3-001 contributes to tumorigenesis of pancreatic cancer by derepressing the miR-3923/KRAS pathway
Q42070258Hypoxic regulation of the noncoding genome and NEAT1.
Q90569836Identification of pancreatic cancer type related factors by Weighted Gene Co-Expression Network Analysis
Q38648079Influence of the interaction between long noncoding RNAs and hypoxia on tumorigenesis
Q26739857Insights into the Regulatory Role of Non-coding RNAs in Cancer Metabolism
Q40056796Linc-ing Circulating Long Non-coding RNAs to the Diagnosis and Malignant Prediction of Intraductal Papillary Mucinous Neoplasms of the Pancreas.
Q55086969Linc00462 promotes pancreatic cancer invasiveness through the miR-665/TGFBR1-TGFBR2/SMAD2/3 pathway.
Q35970147Linc00675 is a novel marker of short survival and recurrence in patients with pancreatic ductal adenocarcinoma
Q26739062Liquid biopsy in patients with pancreatic cancer: Circulating tumor cells and cell-free nucleic acids
Q35793883LncRNA-ATB promotes trastuzumab resistance and invasion-metastasis cascade in breast cancer
Q26739965LncRNAs in pancreatic cancer
Q28088454Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets?
Q37208218Long non-coding RNA TUSC7 acts a molecular sponge for miR-10a and suppresses EMT in hepatocellular carcinoma
Q38645336Long non-coding RNA and tumor hypoxia: new players ushered toward an old arena
Q47099093Long non-coding RNA in pancreatic adenocarcinoma and pancreatic neuroendocrine tumors
Q28069105Long non-coding RNAs: potential new biomarkers for predicting tumor invasion and metastasis
Q64262860Long noncoding RNA DNAJC3-AS1 promotes osteosarcoma progression via its sense-cognate gene DNAJC3
Q33849818Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression.
Q92040048Long noncoding RNA TP53TG1 promotes pancreatic ductal adenocarcinoma development by acting as a molecular sponge of microRNA-96
Q38682910Long noncoding RNAs: emerging regulators of tumor angiogenesis
Q47130796Meta-analysis of the clinical value of abnormally expressed long non-coding RNAs for pancreatic cancer
Q41721796Microarray Analysis of the Expression Profile of Long Non-Coding RNAs Indicates lncRNA RP11-263F15.1 as a Biomarker for Diagnosis and Prognostic Prediction of Pancreatic Ductal Adenocarcinoma
Q33624574Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward
Q91649956Non-coding RNAs in Pancreatic Ductal Adenocarcinoma
Q89148846Non-coding RNAs in pancreatic cancer: challenges and opportunities for clinical application
Q26774630Noncoding RNAs and pancreatic cancer
Q30241331Noncoding RNAs as novel biomarkers in pancreatic cancer: what do we know?
Q50046874Over-expression of long non-coding RNA PTENP1 inhibits cell proliferation and migration via suppression of miR-19b in breast cancer cells
Q38931711Overexpression of long non-coding RNA MALAT1 is correlated with clinical progression and unfavorable prognosis in pancreatic cancer
Q99711125Research progress on long non-coding RNAs and their roles as potential biomarkers for diagnosis and prognosis in pancreatic cancer
Q64272342STIM1 overexpression in hypoxia microenvironment contributes to pancreatic carcinoma progression
Q94547387Signaling in and out: long-noncoding RNAs in tumor hypoxia
Q38644800The Many Faces of Long Noncoding RNAs in Cancer
Q28084785The Triple-Code Model for Pancreatic Cancer: Cross Talk Among Genetics, Epigenetics, and Nuclear Structure
Q48264188The endoplasmic reticulum-associated protein, OS-9, behaves as a lectin in targeting the immature calcium-sensing receptor
Q89514252The interplay between HIF-1α and noncoding RNAs in cancer
Q47624410The involvement of lncRNAs in the development and progression of pancreatic cancer
Q96126784The lncRNA RUNX1-IT1 regulates C-FOS transcription by interacting with RUNX1 in the process of pancreatic cancer proliferation, migration and invasion
Q89638297The multifaceted roles of long noncoding RNAs in pancreatic cancer: an update on what we know
Q55032248Three-lncRNA signature is a potential prognostic biomarker for pancreatic adenocarcinoma.
Q47145983lncRNA MALAT1, HOTTIP and PVT1 as predictors for predicting the efficacy of GEM based chemotherapy in first-line treatment of pancreatic cancer patients

Search more.