| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1040239054 |
| P356 | DOI | 10.1007/S00109-016-1475-3 |
| P932 | PMC publication ID | 5145738 |
| P698 | PubMed publication ID | 27695879 |
| P50 | author | Shuo Qie | Q80664971 |
| P2093 | author name string | J Alan Diehl | |
| P2860 | cites work | Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase | Q24295177 |
| A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells | Q24297823 | ||
| Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase | Q24303548 | ||
| F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage | Q24321698 | ||
| Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛ | Q24337479 | ||
| Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control | Q24522941 | ||
| Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function | Q24554383 | ||
| Systematic analysis and nomenclature of mammalian F-box proteins | Q24561715 | ||
| Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes | Q24563451 | ||
| Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1 | Q24595709 | ||
| Role of the F-box protein Skp2 in lymphomagenesis | Q24603883 | ||
| RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility | Q24647282 | ||
| Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1 | Q24647887 | ||
| Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex | Q24670129 | ||
| Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1) | Q24685138 | ||
| Warburg effect(s)-a biographical sketch of Otto Warburg and his impacts on tumor metabolism | Q26766615 | ||
| Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities | Q36590413 | ||
| Inhibition of granulocyte differentiation by G1 cyclins D2 and D3 but not D1 | Q36710873 | ||
| State of the APC/C: organization, function, and structure | Q36867692 | ||
| A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells | Q36897684 | ||
| Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability | Q36994736 | ||
| Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer | Q37002726 | ||
| CDK inhibitors: cell cycle regulators and beyond | Q37081857 | ||
| Cellular mechanisms of tumour suppression by the retinoblastoma gene. | Q37225340 | ||
| SCF(Fbx4/alphaB-crystallin) E3 ligase: when one is not enough | Q37279728 | ||
| The FBXO4 tumor suppressor functions as a barrier to BRAFV600E-dependent metastatic melanoma | Q37336605 | ||
| Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer. | Q37417571 | ||
| A single NFκB system for both canonical and non-canonical signaling | Q37811890 | ||
| Regulation of cell fate determination by Skp1-Cullin1-F-box (SCF) E3 ubiquitin ligases. | Q37895202 | ||
| Complex Coordination of Cell Plasticity by a PGC-1α-controlled Transcriptional Network in Skeletal Muscle | Q26776167 | ||
| FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance | Q26864654 | ||
| The crystal structure of cyclin A | Q27732570 | ||
| Cyclin D1 in breast cancer pathogenesis | Q27824841 | ||
| Molecular predictors of clinical outcome in patients with head and neck squamous cell carcinoma | Q27824854 | ||
| Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation | Q27851399 | ||
| Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells | Q27860717 | ||
| SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box | Q27936367 | ||
| Targeting CDK4 and CDK6: From Discovery to Therapy | Q28082912 | ||
| Tumor progression and the different faces of the PERK kinase | Q28087036 | ||
| Arginine methylation regulates the p53 response | Q28116284 | ||
| SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 | Q28137860 | ||
| Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
| Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation | Q28140810 | ||
| PERK mediates cell-cycle exit during the mammalian unfolded protein response | Q28141519 | ||
| D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability | Q28144730 | ||
| Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins | Q28201264 | ||
| Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase | Q28202311 | ||
| Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors | Q28202557 | ||
| E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression | Q28216519 | ||
| Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway | Q28237113 | ||
| Cyclin D as a therapeutic target in cancer | Q28242623 | ||
| miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer | Q28249659 | ||
| Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4 | Q28266936 | ||
| WNT2B: comparative integromics and clinical applications (Review) | Q28280669 | ||
| Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization | Q28290083 | ||
| Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
| Cyclin D1: polymorphism, aberrant splicing and cancer risk | Q28303053 | ||
| Requirement for CDK4 kinase function in breast cancer | Q28585905 | ||
| The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation | Q28592198 | ||
| PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway | Q28592902 | ||
| NF-kappaB in cancer: from innocent bystander to major culprit | Q29614603 | ||
| D-type cyclin-dependent kinase activity in mammalian cells | Q29614966 | ||
| The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway | Q29615176 | ||
| SCFs in the new millennium | Q38102567 | ||
| The cell-cycle regulator CDK4: an emerging therapeutic target in melanoma | Q38148748 | ||
| Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present. | Q38175443 | ||
| FOXM1: A key oncofoetal transcription factor in health and disease | Q38234651 | ||
| Palbociclib: first global approval | Q38384741 | ||
| CDK4/6 inhibitors in breast cancer | Q38520201 | ||
| The front and rear of collective cell migration. | Q38685677 | ||
| Antiproliferative effects of CDK4/6 inhibition in CDK4-amplified human liposarcoma in vitro and in vivo | Q38974966 | ||
| Alternative splicing variants of human Fbx4 disturb cyclin D1 proteolysis in human cancer. | Q39007490 | ||
| A novel cell-cycle-indicator, mVenus-p27K-, identifies quiescent cells and visualizes G0-G1 transition | Q39026816 | ||
| Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication | Q39258788 | ||
| Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α. | Q39321748 | ||
| Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis | Q39444400 | ||
| Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts | Q39610954 | ||
| Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68 | Q39760025 | ||
| Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1. | Q40022664 | ||
| Peroxisome proliferator-activated receptor gamma-independent suppression of androgen receptor expression by troglitazone mechanism and pharmacologic exploitation | Q40149307 | ||
| Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1. | Q40274206 | ||
| An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene | Q40617469 | ||
| Skp2 regulates Myc protein stability and activity | Q40644685 | ||
| p21(Cip1) Promotes cyclin D1 nuclear accumulation via direct inhibition of nuclear export | Q40761763 | ||
| Epidermal growth factor induces cyclin D1 in a human prostate cancer cell line | Q41046866 | ||
| Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase | Q41093702 | ||
| Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. | Q41173912 | ||
| Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling | Q41493003 | ||
| ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis | Q41893268 | ||
| PRMT5-dependent p53 escape in tumorigenesis | Q41893763 | ||
| PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers | Q42702906 | ||
| Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation | Q42801826 | ||
| Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation | Q42803654 | ||
| The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription | Q44455864 | ||
| Wnt2 protein plays a role in the progression of pancreatic cancer promoted by pancreatic stellate cells | Q44538045 | ||
| Cyclin D1 gene (CCND1) mutations in endometrial cancer | Q44573130 | ||
| A census of amplified and overexpressed human cancer genes | Q44951771 | ||
| Expression of cyclin D1 splice variants is differentially associated with outcome in non-small cell lung cancer patients. | Q45909642 | ||
| Cyclin-dependent kinases regulate the antiproliferative function of Smads | Q47229633 | ||
| Molecular alterations associated with cyclin D1 overexpression in endometrial cancer | Q47802550 | ||
| Correlation of cyclin D1 and cyclin D3 overexpression with the loss of PTEN expression in endometrial carcinoma. | Q53607647 | ||
| Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage | Q57188003 | ||
| Epidermal growth factor induces cyclin D1 in human pancreatic carcinoma: evidence for a cyclin D1-dependent cell cycle progression | Q74599650 | ||
| A family outing: small GTPases cyclin' through G1 | Q77199408 | ||
| PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling | Q89146054 | ||
| ERBB receptors and cancer: the complexity of targeted inhibitors | Q29619520 | ||
| Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma | Q33706095 | ||
| Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains | Q33735612 | ||
| Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression | Q33827309 | ||
| Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene | Q33865182 | ||
| Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway | Q33884776 | ||
| Cell-cycle dysregulation and the molecular mechanisms of prostate cancer | Q33890428 | ||
| NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. | Q33959017 | ||
| Specific protection against breast cancers by cyclin D1 ablation | Q34082446 | ||
| Role of Pirh2 in mediating the regulation of p53 and c-Myc | Q34085616 | ||
| Selective CREB-dependent cyclin expression mediated by the PI3K and MAPK pathways supports glioma cell proliferation | Q34113332 | ||
| ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice | Q34252194 | ||
| Ubiquitin-dependent proteolysis in G1/S phase control and its relationship with tumor susceptibility | Q34346963 | ||
| Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. | Q34415250 | ||
| Molecular prognostic markers in pancreatic cancer: a systematic review | Q34560651 | ||
| Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of peroxisome proliferator-activated receptor gamma | Q34637659 | ||
| The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation | Q34835596 | ||
| Linking cyclins to transcriptional control. | Q35012861 | ||
| A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers | Q35099578 | ||
| Molecular pathogenesis of head and neck squamous cell carcinoma | Q35123594 | ||
| Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms. | Q35219426 | ||
| Targeting cell cycle regulators in hematologic malignancies. | Q35334436 | ||
| Cyclin D1 represses gluconeogenesis via inhibition of the transcriptional coactivator PGC1α | Q35360473 | ||
| Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression | Q35552863 | ||
| Genetic reevaluation of the role of F-box proteins in cyclin D1 degradation | Q35697802 | ||
| Changing gears in Nrf1 research, from mechanisms of regulation to its role in disease and prevention | Q35740428 | ||
| Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival | Q35828800 | ||
| Inhibition of CDK-mediated phosphorylation of Smad3 results in decreased oncogenesis in triple negative breast cancer cells | Q36187896 | ||
| Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins | Q36310068 | ||
| Smad3 phosphorylation by cyclin-dependent kinases | Q36313453 | ||
| Update on the molecular biology of mantle cell lymphoma | Q36364527 | ||
| Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells | Q36552538 | ||
| Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1. | Q36568076 | ||
| The role of cell cycle regulatory proteins in the pathogenesis of melanoma. | Q36568961 | ||
| P433 | issue | 12 | |
| P304 | page(s) | 1313-1326 | |
| P577 | publication date | 2016-10-02 | |
| P1433 | published in | Journal of Molecular Medicine | Q6295593 |
| P1476 | title | Cyclin D1, cancer progression, and opportunities in cancer treatment | |
| P478 | volume | 94 |
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| Q93019418 | CCDN1 rs603965 polymorphism may serve as a genetic biomarker of brain tumor: A meta-analysis of 5,769 subjects |
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