New insights into the functions of PIGF, a protein involved in the ethanolamine phosphate transfer steps of glycosylphosphatidylinositol biosynthesis

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New insights into the functions of PIGF, a protein involved in the ethanolamine phosphate transfer steps of glycosylphosphatidylinositol biosynthesis is …
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scholarly articleQ13442814

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P356DOI10.1042/BJ20140541
P698PubMed publication ID25074286

P50authorYasu S MoritaQ58080118
P2093author name stringTaroh Kinoshita
Yoshiko Murakami
Yusuke Maeda
Matthew J Stokes
P2860cites workPIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulumQ24317767
GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositolQ24337407
Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannoseQ27934630
GPI7 involved in glycosylphosphatidylinositol biosynthesis is essential for yeast cell separation.Q27938657
Deletion of GPI7, a yeast gene required for addition of a side chain to the glycosylphosphatidylinositol (GPI) core structure, affects GPI protein transport, remodeling, and cell wall integrityQ27939479
MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeastQ27939818
Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositolQ28511718
SOSUI: classification and secondary structure prediction system for membrane proteinsQ29616676
Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositolQ33881662
Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesisQ33887644
Multiple congenital anomalies-hypotonia-seizures syndrome is caused by a mutation in PIGN.Q34178475
Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly.Q36425692
Biosynthesis, remodelling and functions of mammalian GPI-anchored proteins: recent progressQ37219317
Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin.Q38362425
YLL031c belongs to a novel family of membrane proteins involved in the transfer of ethanolaminephosphate onto the core structure of glycosylphosphatidylinositol anchors in yeastQ42626792
Glycosylphosphatidylinositol (GPI) proteins of Saccharomyces cerevisiae contain ethanolamine phosphate groups on the alpha1,4-linked mannose of the GPI anchorQ44777439
PIGN mutations cause congenital anomalies, developmental delay, hypotonia, epilepsy, and progressive cerebellar atrophyQ45259377
Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membraneQ58867303
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)249-256
P577publication date2014-10-01
P1433published inBiochemical JournalQ864221
P1476titleNew insights into the functions of PIGF, a protein involved in the ethanolamine phosphate transfer steps of glycosylphosphatidylinositol biosynthesis
P478volume463