| scholarly article | Q13442814 |
| P2093 | author name string | Yi Li | |
| Lihui Wang | |||
| Ping Gong | |||
| Kang Chen | |||
| Chunfu Wu | |||
| Jingyu Yang | |||
| Yanfang Zhao | |||
| Shu Xiao | |||
| Wufu Zhu | |||
| Fangyang Wang | |||
| Guanfang Ping | |||
| P2860 | cites work | IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer | Q24292870 |
| Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways | Q24594585 | ||
| PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition | Q28237935 | ||
| Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3 | Q28256422 | ||
| Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy | Q28260415 | ||
| Discovery and canine preclinical assessment of a nontoxic procaspase-3-activating compound | Q28292596 | ||
| The biochemistry of apoptosis | Q29547741 | ||
| Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice | Q33982420 | ||
| Apoptotic pathways: paper wraps stone blunts scissors | Q33993406 | ||
| Caspase activation: revisiting the induced proximity model | Q34328287 | ||
| Apoptosis: a link between cancer genetics and chemotherapy | Q34520432 | ||
| Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants | Q34592925 | ||
| Human caspases: activation, specificity, and regulation | Q34608215 | ||
| Survivin and IAP proteins in cell-death mechanisms | Q35414780 | ||
| The inhibitors of apoptosis: there is more to life than Bcl2. | Q35591690 | ||
| Novel Polypyridyl chelators deplete cellular zinc and destabilize the X-linked inhibitor of apoptosis protein (XIAP) prior to induction of apoptosis in human prostate and breast cancer cells. | Q36044333 | ||
| Targeting the IAP family of caspase inhibitors as an emerging therapeutic strategy. | Q36320283 | ||
| Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis and sensitizes prostate cancer cells to TRAIL-mediated apoptosis | Q36979121 | ||
| Clinical development of novel proteasome inhibitors for cancer treatment | Q37136598 | ||
| X-linked Inhibitor of Apoptosis: A Chemoresistance Factor or a Hollow Promise | Q37777537 | ||
| Caspase substrates and cellular remodeling | Q37860318 | ||
| GDC-0941 sensitizes breast cancer to ABT-737 in vitro and in vivo through promoting the degradation of Mcl-1. | Q39526634 | ||
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| Caspase-3 mediated feedback activation of apical caspases in doxorubicin and TNF-alpha induced apoptosis | Q40225214 | ||
| Increased expression of Apaf-1 and procaspase-3 and the functionality of intrinsic apoptosis apparatus in non-small cell lung carcinoma | Q40564217 | ||
| Overexpression of caspase-3 in hepatocellular carcinomas | Q40564617 | ||
| Substrate cleavage by caspases generates protein fragments with Smac/Diablo-like activities | Q40623378 | ||
| Elevated procaspase levels in human melanoma | Q40789256 | ||
| Characterization of the interleukin-1beta-converting enzyme/ced-3-family protease, caspase-3/CPP32, in Hodgkin's disease: lack of caspase-3 expression in nodular lymphocyte predominance Hodgkin's disease | Q42796334 | ||
| Procaspase-activating compound 1 induces a caspase-3-dependent cell death in cerebellar granule neurons. | Q42967264 | ||
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| Direct in vivo evidence of protective effects of grape seed procyanidin fractions and other antioxidants against ethanol-induced oxidative DNA damage in mouse brain cells | Q48137040 | ||
| High levels of expression and nuclear localization of interleukin-1 beta converting enzyme (ICE) and CPP32 in favorable human neuroblastomas. | Q48616022 | ||
| Differential effects of haloperidol, clozapine and olanzapine on learning and memory functions in mice. | Q51980976 | ||
| Targeting apoptosis: selected anticancer strategies | Q82771838 | ||
| P433 | issue | 8 | |
| P921 | main subject | gallbladder cancer | Q977787 |
| xenograft | Q64148587 | ||
| P304 | page(s) | 1640-1652 | |
| P577 | publication date | 2014-07-03 | |
| P1433 | published in | Molecular Oncology | Q2190736 |
| P1476 | title | A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts | |
| P478 | volume | 8 |
| Q92170162 | Anticancer activity of newly synthesized 1,1-disubstituted cyclohexane-1-carboxamides: in vitro caspases mediated apoptosis activators in human cancer cell lines and their molecular modeling |
| Q50252190 | Antioxidant acetophenone glycosides from the roots of Euphorbia ebracteolata Hayata |
| Q91879123 | Companion animals in comparative oncology: One Medicine in action |
| Q35859325 | Derivatives of Procaspase-Activating Compound 1 (PAC-1) and their Anticancer Activities |
| Q34455521 | Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells |
| Q49822760 | Multiple mechanisms of zinc-mediated inhibition for the apoptotic caspases -3, -6, -7, & -8. |
| Q90068431 | Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials |
| Q60915212 | Procaspase activating compound 1 controls tetracycline repressor-regulated gene expression system |
| Q57025388 | Procaspase-3-activating compound 1 stabilizes hypoxia-inducible factor 1α and induces DNA damage by sequestering ferrous iron |
| Q35598226 | Removal of Metabolic Liabilities Enables Development of Derivatives of Procaspase-Activating Compound 1 (PAC-1) with Improved Pharmacokinetics |
| Q38753997 | SM-1, a novel PAC-1 derivative, activates procaspase-3 and causes cancer cell apoptosis |
| Q29027136 | Small-Molecule Procaspase-3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics |
| Q46549141 | Synergistic and targeted therapy with a procaspase-3 activator and temozolomide extends survival in glioma rodent models and is feasible for the treatment of canine malignant glioma patients |
| Q35995093 | Targeting procaspase-3 with WF-208, a novel PAC-1 derivative, causes selective cancer cell apoptosis |
| Q38764663 | The Combination of Vemurafenib and Procaspase-3 Activation Is Synergistic in Mutant BRAF Melanomas |
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