Identification of a Membrane Protein Required for Lipomannan Maturation and Lipoarabinomannan Synthesis in Corynebacterineae.

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Identification of a Membrane Protein Required for Lipomannan Maturation and Lipoarabinomannan Synthesis in Corynebacterineae. is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M116.772202
P8608Fatcat IDrelease_44d53i5w6jgwndhednv3te2vw4
P932PMC publication ID5377810
P698PubMed publication ID28167532

P50authorRoss L. CoppelQ37378539
Paul K CrellinQ56811704
Yoshiki Yamaryo-BottéQ58330052
Stephan KlattQ84617934
P2093author name stringMalcolm J McConville
Rajini Brammananth
Tamaryn J Cashmore
Arek K Rainczuk
P2860cites workHigh-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolismQ21131409
The Envelope of MycobacteriaQ22241995
Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferaseQ24656511
Basic local alignment search toolQ25938991
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectorsQ26778475
The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding ModuleQ27667217
Genes required for mycobacterial growth defined by high density mutagenesisQ27976512
Mycobacterial lipoarabinomannan: an extraordinary lipoheteroglycan with profound physiological effectsQ28260573
The reductase that catalyzes mycolic motif synthesis is required for efficient attachment of mycolic acids to arabinogalactanQ28288829
Mycolic acids: structure, biosynthesis and physiological functionsQ28289888
Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteriaQ28486491
Inactivation of Corynebacterium glutamicum NCgl0452 and the role of MgtA in the biosynthesis of a novel mannosylated glycolipid involved in lipomannan biosynthesisQ28486527
Identification of an alpha(1-->6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosisQ28486750
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosisQ28486804
Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosisQ28486808
Analysis of a new mannosyltransferase required for the synthesis of phosphatidylinositol mannosides and lipoarbinomannan reveals two lipomannan pools in corynebacterineaeQ28487340
Lipoarabinomannan of Mycobacterium: mannose capping by a multifunctional terminal mannosyltransferaseQ28487622
Identification of a novel protein with a role in lipoarabinomannan biosynthesis in mycobacteriaQ28487629
PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteriaQ28501849
Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium speciesQ28501856
Characterization of the Corynebacterium glutamicum deltapimB' deltamgtA double deletion mutant and the role of Mycobacterium tuberculosis orthologues Rv2188c and Rv0557 in glycolipid biosynthesisQ28854137
Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicumQ29615259
New use of BCG for recombinant vaccinesQ29615313
Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan coreQ33220238
Genetic basis for the synthesis of the immunomodulatory mannose caps of lipoarabinomannan in Mycobacterium tuberculosisQ33243649
Roles of lipoarabinomannan in the pathogenesis of tuberculosisQ33804092
Topology and mutational analysis of the single Emb arabinofuranosyltransferase of Corynebacterium glutamicum as a model of Emb proteins of Mycobacterium tuberculosisQ34579687
Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic responseQ34727406
Protter: interactive protein feature visualization and integration with experimental proteomic dataQ35026816
Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branchingQ35069666
Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interactionQ35589680
The lipoprotein LpqW is essential for the mannosylation of periplasmic glycolipids in Corynebacteria.Q36466653
Identification of a novel alpha(1-->6) mannopyranosyltransferase MptB from Corynebacterium glutamicum by deletion of a conserved gene, NCgl1505, affords a lipomannan- and lipoarabinomannan-deficient mutant.Q36737388
Structural characterization and functional properties of a novel lipomannan variant isolated from a Corynebacterium glutamicum pimB' mutantQ36785028
AftD, a novel essential arabinofuranosyltransferase from mycobacteriaQ37376674
Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunityQ37658428
Binding of the terminal mannosyl units of lipoarabinomannan from a virulent strain of Mycobacterium tuberculosis to human macrophages.Q38309145
Assembly of the Mycobacterial Cell WallQ38612990
Drug sensitivity and environmental adaptation of mycobacterial cell wall components.Q41129978
Structure-Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosisQ42114687
The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the mannose caps on lipoarabinomannanQ44258976
Function of phosphatidylinositol in mycobacteria.Q45213296
Identification of macrophage induced genes of Corynebacterium pseudotuberculosis by differential fluorescence induction.Q46620527
Acetylation of trehalose mycolates is required for efficient MmpL-mediated membrane transport in Corynebacterineae.Q46810092
Relationships between the structure and the roles of lipoarabinomannans and related glycoconjugates in tuberculosis pathogenesisQ47716293
A heat shock following electroporation induces highly efficient transformation of Corynebacterium glutamicum with xenogeneic plasmid DNA.Q52537077
Mycobacterium tuberculosis surface protein Rv0227c contains high activity binding peptides which inhibit cell invasion.Q54290954
Identification of a Novel Arabinofuranosyltransferase AftB Involved in a Terminal Step of Cell Wall Arabinan Biosynthesis in Corynebacterianeae, such asCorynebacterium glutamicumandMycobacterium tuberculosisQ58040456
The Carboxy Terminus of EmbC fromMycobacterium smegmatisMediates Chain Length Extension of the Arabinan in LipoarabinomannanQ62736137
Structures of the glycoinositolphospholipids from Leishmania major. A family of novel galactofuranose-containing glycolipidsQ68416565
Structure of the lipophosphoglycan from Leishmania majorQ68612587
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectLipoarabinomannanQ6556678
membrane proteinQ423042
P304page(s)4976-4986
P577publication date2017-02-06
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of a Membrane Protein Required for Lipomannan Maturation and Lipoarabinomannan Synthesis in Corynebacterineae
P478volume292

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cites work (P2860)
Q94550843Adaptive laboratory evolution enhances methanol tolerance and conversion in engineered Corynebacterium glutamicum
Q92867274Cell Walls and Membranes of Actinobacteria
Q90296276Global phenotypic profiling identifies a conserved actinobacterial cofactor for a bifunctional PBP-type cell wall synthase
Q90689402MtrP, a putative methyltransferase in Corynebacteria, is required for optimal membrane transport of trehalose mycolates
Q92573014Mycobacterial phosphatase PstP regulates global serine threonine phosphorylation and cell division
Q92153747The MmpL3 interactome reveals a complex crosstalk between cell envelope biosynthesis and cell elongation and division in mycobacteria
Q47881584The cell envelope-associated phospholipid-binding protein LmeA is required for mannan polymerization in mycobacteria

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