Expression profiling and functional implications of a set of zinc finger proteins, ZNF423, ZNF470, ZNF521, and ZNF780B, in primary osteoarthritic articular chondrocytes.

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Expression profiling and functional implications of a set of zinc finger proteins, ZNF423, ZNF470, ZNF521, and ZNF780B, in primary osteoarthritic articular chondrocytes. is …
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scholarly articleQ13442814

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P356DOI10.1155/2014/318793
P932PMC publication ID4058293
P698PubMed publication ID24976683
P5875ResearchGate publication ID263514518

P50authorHeather Mandy BondQ67561896
Emanuela ChiarellaQ50628392
Maria MesuracaQ59689489
Stefania ScicchitanoQ59692824
Olimpio GalassoQ38328741
P2093author name stringGiovanni Morrone
Giorgio Gasparini
Renaud Vatrinet
Leonardo Guido
P2860cites workOAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathwaysQ22011195
ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcomeQ24313063
The transcription factor Zfp423/OAZ is required for cerebellar development and CNS midline patterning.Q24624584
Zfp423/OAZ participates in a developmental switch during olfactory neurogenesisQ24624658
Zfp423 is required for normal cerebellar developmentQ24670342
Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation.Q24677635
The Age-Related Changes in Cartilage and OsteoarthritisQ26863325
Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cellsQ28186069
Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal developmentQ28238235
OAZ regulates bone morphogenetic protein signaling through Smad6 activationQ28288378
Identification of DNA recognition sequences and protein interaction domains of the multiple-Zn-finger protein RoazQ28569186
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralizationQ28590890
ZFP423 coordinates Notch and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expressionQ28592502
Characterization and chondrocyte differentiation stage-specific expression of KRAB zinc-finger protein gene ZNF470.Q33205656
The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip.Q33542090
Transcriptional control of preadipocyte determination by Zfp423.Q33753951
Osteoarthrosis of the knee. A radiographic investigationQ72177931
Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilageQ81057971
Gene expression and localization of high-mobility group box chromosomal protein-1 (HMGB-1)in human osteoarthritic cartilageQ83094750
Autologous chondrocyte implantation: a systematic reviewQ85035498
Adult cartilage-specific peroxisome proliferator-activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotypeQ86044160
Zinc finger protein 521 antagonizes early B-cell factor 1 and modulates the B-lymphoid differentiation of primary hematopoietic progenitors.Q50628309
Regulation of type II collagen expression by histone deacetylase in articular chondrocytesQ51027080
Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemiaQ51807564
Intrinsic transition of embryonic stem-cell differentiation into neural progenitorsQ51888586
Culture and phenotyping of chondrocytes in primary cultureQ60531365
Zfp521 Is a Target Gene and Key Effector of Parathyroid Hormone-Related Peptide Signaling in Growth Plate ChondrocytesQ34217226
Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cellsQ34361233
Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activityQ34439684
Regulation of early adipose commitment by Zfp521.Q34499279
Early hematopoietic zinc finger protein-zinc finger protein 521: a candidate regulator of diverse immature cells.Q34633547
The role of zinc finger protein 521/early hematopoietic zinc finger protein in erythroid cell differentiationQ34892726
Early hematopoietic zinc finger protein prevents tumor cell recognition by natural killer cellsQ34973901
Sonic hedgehog improves redifferentiation of dedifferentiated chondrocytes for articular cartilage repairQ35095410
Interleukin-1 beta-modulated gene expression in immortalized human chondrocytesQ35824517
Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytesQ35893262
Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritisQ36111296
Recent findings on the role of gelatinases (matrix metalloproteinase-2 and -9) in osteoarthritisQ36140890
Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiationQ36245462
The chondrocyte: biology and clinical applicationQ36556685
WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.Q36616934
Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor-binding protein 3 (IGFBP-3) in human chondrocytesQ36633155
Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineagesQ36822669
Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase.Q37021544
Transcriptional regulators of chondrocyte hypertrophy.Q37188794
Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemiaQ37246514
Cartilage homeostasis in health and rheumatic diseasesQ37270714
Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivoQ37351658
RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processesQ37584730
Regulatory functions of insulin-like growth factor binding proteins in osteoarthritis.Q37888841
Gene expression profiling of primary human articular chondrocytes in high-density micromasses reveals patterns of recovery, maintenance, re- and dedifferentiationQ38344379
Zfp60, a mouse zinc finger gene expressed transiently during in vitro muscle differentiationQ38356902
The zinc finger transcription factor Zfp60 is a negative regulator of cartilage differentiationQ38360058
Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism AssociationQ39513001
Molecular phenotyping of human chondrocyte cell lines T/C-28a2, T/C-28a4, and C-28/I2.Q40607718
Chondrocyte-intrinsic Smad3 represses Runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis.Q41964841
Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytesQ42109507
The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressorsQ42824184
Culture of chondrocytes in alginate beadsQ44997817
Identification of transcription regulatory relationships in rheumatoid arthritis and osteoarthritisQ45400598
Chondrocytes from patients with osteoarthritis express typical extracellular matrix molecules once grown onto a three-dimensional hyaluronan-based scaffold.Q45988444
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectosteoarthritisQ62736
P304page(s)318793
P577publication date2014-05-27
P1433published inMediators of InflammationQ2144494
P1476titleExpression profiling and functional implications of a set of zinc finger proteins, ZNF423, ZNF470, ZNF521, and ZNF780B, in primary osteoarthritic articular chondrocytes
P478volume2014

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cites work (P2860)
Q35689414Computational Modeling of a Transcriptional Switch Underlying B-Lymphocyte Lineage Commitment of Hematopoietic Multipotent Cells
Q90317170The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway
Q35515230UMG Lenti: novel lentiviral vectors for efficient transgene- and reporter gene expression in human early hematopoietic progenitors.
Q26770729ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies
Q55385618ZNF423: A New Player in Estrogen Receptor-Positive Breast Cancer.
Q89228189ZNF521 Has an Inhibitory Effect on the Adipogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells
Q96305086Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells

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