Gastrointestinal methionine shuttle: Priority handling of precious goods

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Gastrointestinal methionine shuttle: Priority handling of precious goods is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/IUB.1571
P698PubMed publication ID27753190

P2093author name stringJörg R Aschenbach
Gerhard Sponder
Lucia Mastrototaro
Behnam Saremi
P2860cites workCloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+)Q22003724
Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intoleranceQ22008055
LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestineQ22010848
Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system iminoQ24337439
Molecular cloning of the mouse IMINO system: an Na+- and Cl--dependent proline transporterQ24528165
The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamineQ24532093
Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter familyQ24533490
Methionine residues as endogenous antioxidants in proteinsQ24658367
Role of homocysteine in the development of cardiovascular diseaseQ27004318
Bacterial methionine biosynthesisQ28242168
Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human geneQ28247856
Cloning, mapping and RNA analysis of the human methionine synthase geneQ28299625
Causes of phosphate stone formation and the importance of metaphylaxis by urinary acidification: a reviewQ28375977
Characterization of L-leucine transport system in brush border membranes from human and rabbit small intestineQ28377265
Demyelination of the brain is associated with methionine adenosyltransferase I/III deficiencyQ28379066
Luminal kidney and intestine SLC6 amino acid transporters of B0AT-cluster and their tissue distribution in Mus musculusQ28504781
Identification of LAT4, a novel amino acid transporter with system L activityQ28513311
Luminal leptin inhibits L-glutamine transport in rat small intestine: involvement of ASCT2 and B0AT1Q28570063
A novel system A isoform mediating Na+/neutral amino acid cotransportQ28570693
Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)Q28570781
System A amino acid transporter SNAT2 shows subtype-specific affinity for betaine and hyperosmotic inducibility in placental trophoblastsQ28581373
Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidasesQ28582178
Human LAT1, a subunit of system L amino acid transporter: molecular cloning and transport functionQ30650038
Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons.Q30913408
Expression cloning of a cDNA from rabbit kidney cortex that induces a single transport system for cystine and dibasic and neutral amino acidsQ30989726
Characteristics of transport of selenoamino acids by epithelial amino acid transportersQ33374894
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transportersQ33940393
Adverse Effects of Excessive Consumption of Amino AcidsQ34055066
Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteineQ34326009
Redox modulation of cellular signaling and metabolism through reversible oxidation of methionine sensors in calcium regulatory proteinsQ34389337
Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects.Q34519790
Amino acid transport across mammalian intestinal and renal epitheliaQ34736025
Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart.Q34994245
Regulation of amino acid and glucose transporters in endothelial and smooth muscle cellsQ35035933
Comprehensive profiling of amino acid response uncovers unique methionine-deprived response dependent on intact creatine biosynthesisQ35301052
Methionine transmethylation and transsulfuration in the piglet gastrointestinal tractQ35652279
Characterization and Regulation of the Amino Acid Transporter SNAT2 in the Small Intestine of PigletsQ35673059
Control of muscle protein kinetics by acid-base balanceQ35977143
Modulation of potassium channel function by methionine oxidation and reductionQ36580125
Metabolic regulatory properties of S-adenosylmethionine and S-adenosylhomocysteineQ36982678
Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigsQ37216761
Amino acids and gut functionQ37231774
Oxidation of potassium channels by ROS: a general mechanism of aging and neurodegeneration?Q37619924
Intestinal absorption of protein hydrolysis products: a reviewQ37960463
Modulating protein activity and cellular function by methionine residue oxidationQ37965374
The SLC3 and SLC7 families of amino acid transportersQ38090767
Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporterQ38356396
Role of defective methylation reactions in ethanol-induced dysregulation of intestinal barrier integrityQ38880320
Transport mechanism of (11)C-labeled L- and D-methionine in human-derived tumor cellsQ39314894
Oral methionine in the treatment of severe paracetamol (Acetaminophen) overdoseQ39401635
The light subunit of system b(o,+) is fully functional in the absence of the heavy subunitQ39648305
Methionine Metabolism Alters Oxidative Stress Resistance via the Pentose Phosphate Pathway.Q40023316
Expression of LAT1 and LAT2 amino acid transporters in human and rat intestinal epithelial cellsQ40396046
Oxidation of methionyl residues in proteins: tools, targets, and reversalQ40615542
Identification of a new transport system (y+L) in human erythrocytes that recognizes lysine and leucine with high affinityQ41105126
Regulation of System B0 amino-acid-transport activity in the renal epithelial cell line NBL-1 and concomitant changes in SAAT1 hybridizing transcriptsQ41455043
An inborn error of metabolism with the urinary excretion of alpha-hydroxy-butyric acid and phenylpyruvic acidQ41532236
The osmoregulatory and the amino acid-regulated responses of system A are mediated by different signal transduction pathways.Q41953832
Cloning, functional expression and dietary regulation of the mouse neutral and basic amino acid transporter (NBAT).Q42152660
Methionine concentration in the diet has a tissue-specific effect on chromosomal stability in female miceQ42444785
Apparent absorption of methionine and 2-hydroxy-4-methylthiobutanoic acid from gastrointestinal tract of conventional and gnotobiotic pigsQ42719815
Renal transport of neutral amino acids. Tubular localization of Na+-dependent phenylalanine- and glucose-transport systemsQ42868375
Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availabilityQ43197669
Effect of supplemental methionine on plasma homocysteine concentrations in healthy men: a preliminary study.Q43558289
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell linesQ43737336
Posttranslational alanine trans-stimulation of zwitterionic amino acid transport systems in human intestinal Caco-2 cellsQ43968987
Kinetic model of the brush-border proline/sodium (IMINO) cotransporterQ44236547
Familial hypermethioninemia partially responsive to dietary restrictionQ44559903
Beneficial effects of an amino acid mixture on colonic mucosal healing in ratsQ44584842
Transport of amino acid-based prodrugs by the Na+- and Cl(-) -coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery.Q44655965
Expression of heteromeric amino acid transporters along the murine intestineQ44904875
T-type amino acid transporter TAT1 (Slc16a10) is essential for extracellular aromatic amino acid homeostasis controlQ45797043
High dietary taurine reduces apoptosis and atherosclerosis in the left main coronary artery: association with reduced CCAAT/enhancer binding protein homologous protein and total plasma homocysteine but not lipidemia.Q46034406
Effect of pH on L- and D-methionine uptake across the apical membrane of Caco-2 cells.Q46162510
An amino acid transporter involved in gastric acid secretionQ46820808
Scientific Opinion on DL-methionine, DL-methionine sodium salt, the hydroxy analogue of methionine and the calcium salt of methionine hydroxy analogue in all animal species; on the isopropyl ester of methionine hydroxy analogue and DL-methionine t...Q47151450
Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivityQ47951227
Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPaseQ48304518
Essential amino acid transporter Lat4 (Slc43a2) is required for mouse developmentQ48589485
Ontogeny of the neutral amino acid transporter SNAT1 in the developing rat.Q48748325
Transport properties of a system y+L neutral and basic amino acid transporter. Insights into the mechanisms of substrate recognitionQ48892323
Identification of SLC7A7, encoding y+LAT-1, as the lysinuric protein intolerance gene.Q48922357
Aminoaciduria, but normal thyroid hormone levels and signalling, in mice lacking the amino acid and thyroid hormone transporter Slc7a8.Q49093601
Isolated hypermethioninemia: measurements of S-adenosylmethionine and cholineQ49109131
Differences in plasma metabolomics between sows fed DL-methionine and its hydroxy analogue reveal a strong association of milk composition and neonatal growth with maternal methionine nutrition.Q50603566
Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy.Q51564872
METHIONINE MALABSORPTION IN A MENTALLY DEFECTIVE CHILDQ52135411
Transport of neutral and cationic amino acids across the brush-border membrane of the rabbit ileum.Q52681874
Synthesis of Cysteine from Methionine in Normal Adult Subjects: Effect of Route of AlimentationQ54121801
P433issue12
P304page(s)924-934
P577publication date2016-10-17
P1433published inIUBMB LifeQ15764029
P1476titleGastrointestinal methionine shuttle: Priority handling of precious goods
P478volume68

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cites work (P2860)
Q99604766B Vitamins and One-Carbon Metabolism: Implications in Human Health and Disease
Q47631551Effects of dietary L-methionine supplementation on intestinal integrity and oxidative status in intrauterine growth-retarded weanling piglets
Q91897400Effects of dietary menthol-rich bioactive lipid compounds on zootechnical traits, blood variables and gastrointestinal function in growing sheep
Q38888750Whey protein effects on energy balance link the intestinal mechanisms of energy absorption with adiposity and hypothalamic neuropeptide gene expression

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