The enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon

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The enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.02546-13
P932PMC publication ID4136040
P698PubMed publication ID24890597
P5875ResearchGate publication ID262813299

P50authorJohan NeytsQ29460378
Maria São José NascimentoQ40324882
Dirk JochmansQ56450393
Joana Rocha-PereiraQ56861678
P2093author name stringQ Ma
R Hilgenfeld
M S J Nascimento
P2860cites workStructure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypesQ27619756
Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important ResiduesQ27671472
Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.Q27671667
Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk VirusQ27676085
3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against PicornavirusesQ27676219
Structure of a Murine Norovirus NS6 Protease-Product Complex Revealed by Adventitious CrystallisationQ27681097
Norovirus gastroenteritis in immunocompromised patientsQ27694610
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Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: the importance of primed side interactionsQ28276503
In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C proteaseQ28343611
Statistical estimations in enzyme kineticsQ29620206
In vitro resistance study of rupintrivir, a novel inhibitor of human rhinovirus 3C proteaseQ30443266
Closure of medical departments during nosocomial outbreaks: data from a systematic analysis of the literatureQ31105046
Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assayQ34112325
The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitroQ34504825
Favipiravir (T-705) inhibits in vitro norovirus replicationQ34640499
X-ray crystallographic structure of the Norwalk virus protease at 1.5-A resolutionQ34647772
Systematic literature review of role of noroviruses in sporadic gastroenteritisQ34804404
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Potential use of antiviral agents in polio eradicationQ36944919
Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]Q37093418
The viral polymerase inhibitor 2'-C-methylcytidine inhibits Norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse modelQ37252661
A three-dimensional model to analyze drug-drug interactionsQ37794779
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Selecting and characterizing drug-resistant hepatitis C virus repliconQ42286495
A continuous assay for foot-and-mouth disease virus 3C protease activityQ45401862
The roles of Clostridium difficile and norovirus among gastroenteritis-associated deaths in the United States, 1999-2007.Q47922235
Increasing rates of gastroenteritis hospital discharges in US adults and the contribution of norovirus, 1996-2007.Q51157690
Norovirus in a Dutch tertiary care hospital (2002-2007): frequent nosocomial transmission and dominance of GIIb strains in young childrenQ83193956
Norovirus gastroenteritisQ84800851
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectnorovirusQ1142751
P1104number of pages7
P304page(s)4675-4681
P577publication date2014-06-02
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleThe enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon
P478volume58

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cites work (P2860)
Q38835886A Cell-based Fluorescence Resonance Energy Transfer (FRET) Sensor Reveals Inter- and Intragenogroup Variations in Norovirus Protease Activity and Polyprotein Cleavage
Q91718477A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase
Q36440189Advances Toward a Norovirus Antiviral: From Classical Inhibitors to Lethal Mutagenesis
Q37101808Anti-norovirus therapeutics: a patent review (2010-2015).
Q64115696Automated cell-based luminescence assay for profiling antiviral compound activity against enteroviruses
Q29248430Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions
Q37062340Current tools for norovirus drug discovery
Q38825350Enteroviral proteases: structure, host interactions and pathogenicity.
Q90748454Norovirus antivirals: Where are we now?
Q37517465Recent Advances in the Discovery of Norovirus Therapeutics
Q26796360Role of Marine Natural Products in the Genesis of Antiviral Agents
Q52659751Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells In Vitro.
Q37401695Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds
Q40044140Therapeutics and Immunoprophylaxis Against Noroviruses and Rotaviruses: The Past, Present, and Future
Q91767093Viral replicons as valuable tools for drug discovery

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