Trace levels of mitomycin C disrupt genomic integrity and lead to DNA damage response defect in long-term-cultured human embryonic stem cells

scientific article published on 18 May 2014

Trace levels of mitomycin C disrupt genomic integrity and lead to DNA damage response defect in long-term-cultured human embryonic stem cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1015549674
P356DOI10.1007/S00204-014-1250-6
P698PubMed publication ID24838295
P5875ResearchGate publication ID262422276

P50authorYi SunQ87716739
P2093author name stringGuang-Xiu Lu
Ge Lin
Qing Zheng
Qi Ouyang
Bo Xiong
Di Zhou
De-Hua Cheng
Guang-Ying Lu
Ping-Yuan Xie
Si-Cong Zeng
Wei-Ling Tang
Xiao-Ying Zhou
P2860cites workNucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-linksQ24554288
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cellsQ24616059
Establishment in culture of pluripotential cells from mouse embryosQ27860625
Interaction between ATM protein and c-Abl in response to DNA damageQ28239339
Embryonic stem cell lines from human blastocysts: somatic differentiation in vitroQ29617383
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiationQ29871427
Derivation of Embryonic Stem-Cell Lines from Human BlastocystsQ29999326
Survival responses of human embryonic stem cells to DNA damageQ34078474
Dynamics of the transcriptome response of cultured human embryonic stem cells to ionizing radiation exposureQ34994419
A positive role for c-Abl in Atm and Atr activation in DNA damage response.Q35092564
Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cellsQ35129565
Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instabilityQ35828731
Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cellsQ35924505
Establishment and maintenance of three Chinese human embryonic stem cell linesQ39728634
Three key variables involved in feeder preparation for the maintenance of human embryonic stem cellsQ39984888
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phaseQ40232134
Genomic alterations in cultured human embryonic stem cellsQ40377467
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cellsQ40544422
Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agentsQ41307866
The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activityQ41735615
Preserving the genetic integrity of human embryonic stem cellsQ44641985
Karyotype of human ES cells during extended culture.Q45101711
Human feeder cells support establishment and definitive endoderm differentiation of human embryonic stem cellsQ46370801
LC-ESI-MSD fast determination of residual mitomycin C in hen aqueous humour after corneal refractive surgeryQ46635384
Telomerase-mediated telomere elongation from human blastocysts to embryonic stem cellsQ46882486
Tumor progression of culture-adapted human embryonic stem cells during long-term cultureQ47715761
The impact of a negligent G2/M checkpoint on genomic instability and cancer induction.Q55044969
P433issue1
P921main subjectDNA damageQ5205747
human embryonic stem cellQ59626782
P304page(s)33-45
P577publication date2014-05-18
P1433published inArchives of ToxicologyQ635837
P1476titleTrace levels of mitomycin C disrupt genomic integrity and lead to DNA damage response defect in long-term-cultured human embryonic stem cells
P478volume89

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cites work (P2860)
Q42803562An optimization protocol for Swiss 3T3 feeder cell growth-arrest by Mitomycin C dose-to-volume derivation strategy
Q42097967Efficient feeder cells preparation system for large-scale preparation and application of induced pluripotent stem cells
Q35209431Occurrence and control of sporadic proliferation in growth arrested Swiss 3T3 feeder cells
Q39439138Paradigm shifts, peregrinations and pixies in ophthalmology

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