scholarly article | Q13442814 |
P50 | author | Brandon B Holmes | Q85308707 |
P2093 | author name string | Tao Shen | |
Holly B Kordasiewicz | |||
Marc I Diamond | |||
Eric E Swayze | |||
Guo Chen | |||
Hien Tran | |||
Sarah L DeVos | |||
Brandon Nichols | |||
Rebecca L Miller | |||
Timothy M Miller | |||
C Frank Bennett | |||
Kathleen M Schoch | |||
Tom A Zanardi | |||
Carey S Kebodeaux | |||
Amy J Wegener | |||
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Does neuroinflammation fan the flame in neurodegenerative diseases? | Q27498993 | ||
Neuropathological stageing of Alzheimer-related changes | Q27860862 | ||
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model | Q28115206 | ||
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models | Q28119018 | ||
The MAPT H1 haplotype is associated with tangle-predominant dementia | Q28271237 | ||
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GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease | Q29417137 | ||
Tau suppression in a neurodegenerative mouse model improves memory function | Q29615831 | ||
Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model | Q29617937 | ||
Propagation of tau pathology in a model of early Alzheimer's disease | Q29620203 | ||
P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating | Q30475074 | ||
Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. | Q30513293 | ||
Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β | Q30539255 | ||
Seizure resistance without parkinsonism in aged mice after tau reduction | Q30587394 | ||
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Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice | Q34102829 | ||
Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy | Q34168139 | ||
Alzheimer's disease: cell-specific pathology isolates the hippocampal formation | Q34261572 | ||
Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis. | Q34283652 | ||
Proteopathic tau seeding predicts tauopathy in vivo. | Q34383788 | ||
Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling | Q34506149 | ||
Antisense oligonucleotide therapy for neurodegenerative disease. | Q34830633 | ||
Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice | Q35496991 | ||
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus | Q35963497 | ||
Assessing burrowing, nest construction, and hoarding in mice | Q36015466 | ||
Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis | Q36073366 | ||
No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice | Q36162472 | ||
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain | Q36169754 | ||
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity | Q36394952 | ||
Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry | Q36408405 | ||
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature | Q36575903 | ||
Results from a phase 1 study of nusinersen (ISIS-SMN(Rx)) in children with spinal muscular atrophy | Q36661721 | ||
Age-appropriate cognition and subtle dopamine-independent motor deficits in aged tau knockout mice | Q36681296 | ||
Direct intraventricular delivery of drugs to the rodent central nervous system | Q36921774 | ||
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study | Q37015657 | ||
Antisense reduction of tau in adult mice protects against seizures | Q37058143 | ||
Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease | Q37093852 | ||
Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model | Q37292146 | ||
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration | Q37340843 | ||
Neuronal activity regulates extracellular tau in vivo | Q37630201 | ||
Frontotemporal dementia: implications for understanding Alzheimer disease | Q37987142 | ||
Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases | Q38289739 | ||
Neurodegenerative disease in 2015: Targeting tauopathies for therapeutic translation | Q38705770 | ||
Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients | Q41046533 | ||
Distinct tau prion strains propagate in cells and mice and define different tauopathies | Q41904960 | ||
Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo. | Q41955482 | ||
Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression | Q43806330 | ||
Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807. | Q45810537 | ||
Accelerated tau pathology with synaptic and neuronal loss in a novel triple transgenic mouse model of Alzheimer's disease | Q46252763 | ||
Impairment of nesting behaviour in 3xTg-AD mice. | Q46767084 | ||
Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice | Q48166478 | ||
Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice | Q48289964 | ||
Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice | Q48650483 | ||
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export. | Q48686425 | ||
Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice. | Q50782460 | ||
Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. | Q50856591 | ||
Inflammation and Alzheimer's disease | Q82323473 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 374 | |
P407 | language of work or name | English | Q1860 |
P577 | publication date | 2017-01-01 | |
P1433 | published in | Science Translational Medicine | Q1573955 |
P1476 | title | Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy | |
P478 | volume | 9 |
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