Hepatokines: unlocking the multi-organ network in metabolic diseases.

scientific article published on 2 June 2015

Hepatokines: unlocking the multi-organ network in metabolic diseases. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00125-015-3634-4
P698PubMed publication ID26032022

P50authorCatherine PosticQ42128947
P2093author name stringJean-Pierre Couty
Alison Iroz
P2860cites workFetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistanceQ42832316
The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetesQ45834496
Circadian rhythm of circulating fibroblast growth factor 21 is related to diurnal changes in fatty acids in humans.Q51379199
Increased serum leukocyte cell-derived chemotaxin 2 (LECT2) levels in obesity and fatty liver.Q54372891
Effects of parabiosis of obese with diabetes and normal miceQ69634353
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunctionQ74191142
Fibroblast growth factor 21 analogue LY2405319 lowers blood glucose in streptozotocin-induced insulin-deficient diabetic mice by restoring brown adipose tissue functionQ85893184
ANGPTL8/betatrophin does not control pancreatic beta cell expansionQ24307433
RETRACTED: Betatrophin: a hormone that controls pancreatic β cell proliferationQ24339335
Inventing new medicines: The FGF21 storyQ26823319
Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytesQ28571616
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic statesQ29615208
A link between hepatic glucose production and peripheral energy metabolism via hepatokinesQ33906438
Fructose ingestion acutely stimulates circulating FGF21 levels in humansQ35040490
Direct inhibitory effects of pioglitazone on hepatic fetuin-A expressionQ35097489
Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in miceQ35698850
Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states.Q36848210
Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver diseaseQ36889026
Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetesQ37374259
The role of hepatokines in metabolismQ38075770
FGF21-based pharmacotherapy--potential utility for metabolic disordersQ38202720
Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in miceQ41862381
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)1699-1703
P577publication date2015-06-02
P1433published inDiabetologiaQ5270140
P1476titleHepatokines: unlocking the multi-organ network in metabolic diseases
P478volume58

Reverse relations

cites work (P2860)
Q42378996A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response
Q47195087Association Between Urinary Alpha1-Microglobulin Levels and Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study
Q44390101Association between Healthy Eating Index-2010 and Fetuin-A Levels in Patients with Type 2 Diabetes: a Case-Control Study
Q36334120Association of leukocyte cell-derived chemotaxin 2 (LECT2) with NAFLD, metabolic syndrome, and atherosclerosis
Q48179147Association of serum betatrophin with fibroblast growth factor-21 in women with polycystic ovary syndrome.
Q33852008Carbohydrates from Sources with a Higher Glycemic Index during Adolescence: Is Evening Rather than Morning Intake Relevant for Risk Markers of Type 2 Diabetes in Young Adulthood?
Q48037644Diabetologia at 50: celebrating half a century of progress in diabetes research and care
Q61445459Effects of exercise training on Fetuin-a in obese, type 2 diabetes and cardiovascular disease in adults and elderly: a systematic review and Meta-analysis
Q57687713European Obesity Summit (EOS) - Joint Congress of EASOand IFSO-EC, Gothenburg, Sweden, June 1 - 4, 2016: Abstracts
Q51027541Expression of angiopoietin-like protein 8 correlates with VEGF in patients with proliferative diabetic retinopathy.
Q47291127Fetuin-A, adiposity-linked insulin resistance and responsiveness to an educational-based weight excess reduction program: a population-based survey in prepubertal schoolchildren
Q39168770Fructose and NAFLD: The Multifaceted Aspects of  Fructose Metabolism
Q92219736Hepatoprotective Effects of a Ruthenium(II) Schiff Base Complex in Rats with Diet-Induced Prediabetes
Q92422669Identification of the Secreted Proteins Originated from Primary Human Hepatocytes and HepG2 Cells
Q26751147Implication of hepatokines in metabolic disorders and cardiovascular diseases
Q38728754Liver innate immune cells and insulin resistance: the multiple facets of Kupffer cells
Q26745839Mechanisms of Diabetes-Induced Liver Damage: The role of oxidative stress and inflammation
Q104484239New Emerging Roles of the Novel Hepatokine SERPINB1 in Type 2 Diabetes Mellitus: Crosstalk with β-Cell Dysfunction and Dyslipidemia
Q41663528Organ-Organ Crosstalk and Alcoholic Liver Disease
Q35928495Pathogenesis of nonalcoholic steatohepatitis
Q86743265Plasma fetuin-A does not correlate with monocyte TLR4 in humans
Q39145046Postweaning changes in the expression of chemerin and its receptors in calves are associated with the modification of glucose metabolism
Q61455151Relationship of Circulating Fetuin-A Levels with Body Size and Metabolic Phenotypes
Q47365110Relationship of Serum Fetuin A with Metabolic and Clinical Parameters in German Children and Adolescents with Type 1 Diabetes
Q26753189The Impact of Organokines on Insulin Resistance, Inflammation, and Atherosclerosis
Q36413070The association between circulating fetuin-A levels and type 2 diabetes mellitus risk: systematic review and meta-analysis of observational studies
Q38845636The potential of endurance exercise-derived exosomes to treat metabolic diseases.
Q36302698Visceral fat area is a strong predictor of leukocyte cell-derived chemotaxin 2, a potential biomarker of dyslipidemia

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