Radium-223 dichloride for the treatment of bone metastatic castration-resistant prostate cancer: an evaluation of its safety

scientific article published on 28 May 2015

Radium-223 dichloride for the treatment of bone metastatic castration-resistant prostate cancer: an evaluation of its safety is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1517/14740338.2015.1045874
P698PubMed publication ID26022669

P2093author name stringSten Nilsson
P2860cites workSystemic therapy in men with metastatic castration-resistant prostate cancer:American Society of Clinical Oncology and Cancer Care Ontario clinical practice guidelineQ26852544
Sequential use of novel therapeutics in advanced prostate cancer following docetaxel chemotherapyQ27022715
Prostate cancer: ESMO Consensus Conference Guidelines 2012Q27022847
Alpha emitter radium-223 and survival in metastatic prostate cancerQ29617472
Rituximab, methotrexate, procarbazine, and vincristine followed by consolidation reduced-dose whole-brain radiotherapy and cytarabine in newly diagnosed primary CNS lymphoma: final results and long-term outcomeQ30457046
Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: a prespecified subgroup analysis from the randomised, double-blind, [...]Q33418967
Phase I pharmacokinetic and biodistribution study with escalating doses of ²²³Ra-dichloride in men with castration-resistant metastatic prostate cancer.Q33789188
First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastasesQ34426777
High-linear energy transfer irradiation targeted to skeletal metastases by the alpha-emitter 223Ra: adjuvant or alternative to conventional modalities?Q34576371
Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study.Q34633758
18F-fluoride PET: changes in uptake as a method to assess response in bone metastases from castrate-resistant prostate cancer patients treated with 223Ra-chloride (Alpharadin)Q35335407
A bone marrow toxicity model for ²²³Ra alpha-emitter radiopharmaceutical therapy.Q36235572
Therapeutic strategies for bone metastases and their clinical sequelae in prostate cancerQ36840731
Characterising the castration-resistant prostate cancer population: a systematic reviewQ37945316
A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer.Q37985149
Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trialQ38212374
Alpha-emitter radium-223 in the management of solid tumors: current status and future directionsQ38214287
Castration-resistant prostate cancer: latest evidence and therapeutic implicationsQ38233358
Antiangiogenic agents, chemotherapy, and the treatment of metastatic transitional cell carcinomaQ44080958
A randomized, double-blind, dose-finding, multicenter, phase 2 study of radium chloride (Ra 223) in patients with bone metastases and castration-resistant prostate cancerQ44872720
Phase II study of treatment of advanced ovarian cancer with folate-receptor-targeted therapeutic (vintafolide) and companion SPECT-based imaging agent (99mTc-etarfolatide).Q53073221
Two-year survival follow-up of the randomized, double-blind, placebo-controlled phase II study of radium-223 chloride in patients with castration-resistant prostate cancer and bone metastases.Q53716562
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectradiumQ1128
prostate cancerQ181257
P304page(s)1127-1136
P577publication date2015-05-28
P1433published inExpert Opinion on Drug SafetyQ5421206
P1476titleRadium-223 dichloride for the treatment of bone metastatic castration-resistant prostate cancer: an evaluation of its safety
P478volume14

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cites work (P2860)
Q33438310A Retrospective Analysis of the First 41 mCRPC Patients with Bone Pain Treated with Radium-223 at the National Institute of Oncology in Hungary
Q55158890A Systematic Review of Clinical Practice Guidelines for Castration-Resistant Prostate Cancer.
Q53817267Nuclear medicine and the revolution in the modern management of castration-resistant prostate cancer patients: from (223)Ra-dichloride to new horizons for therapeutic response assessment.
Q39970827Patient-reported quality-of-life analysis of radium-223 dichloride from the phase III ALSYMPCA study
Q48144362Ra-224 Labeling of Calcium Carbonate Microparticles for Internal α-Therapy: Preparation, Stability and Biodistribution in Mice.
Q28079918Radionuclide Therapies in Prostate Cancer: Integrating Radium-223 in the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

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