Inhibition enhancer of zeste homologue 2 promotes senescence and apoptosis induced by doxorubicin in p53 mutant gastric cancer cells

scientific article published on 16 April 2014

Inhibition enhancer of zeste homologue 2 promotes senescence and apoptosis induced by doxorubicin in p53 mutant gastric cancer cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/CPR.12103
P932PMC publication ID6495717
P698PubMed publication ID24738879

P2093author name stringG Wang
J Chen
F Xu
M Cai
M Ma
K Tao
J Bai
X Shuai
P2860cites workGlobal cancer statisticsQ22241238
Cellular senescence: when bad things happen to good cellsQ29615561
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescenceQ29620428
The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survivalQ33705252
Mechanisms of regulatory diversity within the p53 transcriptional networkQ34039841
Molecular characteristics of eight gastric cancer cell lines established in JapanQ34099128
EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expressionQ34803805
Pathological cyclic strain-induced apoptosis in human periodontal ligament cells through the RhoGDIα/caspase-3/PARP pathwayQ35018443
Tumor cell senescence in cancer treatmentQ35143435
Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damageQ35302120
SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK.Q36409515
Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndromeQ36580567
Targeting the MDM2-p53 interaction for cancer therapyQ37177586
The Bmi-1 polycomb group gene in skin cancer: regulation of function by (-)-epigallocatechin-3-gallateQ37233196
Roles of the EZH2 histone methyltransferase in cancer epigeneticsQ37250591
Epigenetic factors in cancer development: polycomb group proteinsQ37822735
p53 as an intervention target for cancer and agingQ38152454
Let-7a inhibits proliferation and induces apoptosis by targeting EZH2 in nasopharyngeal carcinoma cellsQ38495053
Downregulation of Ezh2 expression by RNA interference induces cell cycle arrest in the G0/G1 phase and apoptosis in U87 human glioma cellsQ39275514
EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence.Q39433602
Weak p53 permits senescence during cell cycle arrestQ39635569
DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cellsQ39703300
Enhancer of zeste homolog 2 expression is associated with tumor cell proliferation and metastasis in gastric cancerQ39743771
Growth stimulation leads to cellular senescence when the cell cycle is blockedQ39925937
Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer.Q40273857
Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2.Q53121833
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapyQ74117541
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectdoxorubicinQ18936
P304page(s)211-218
P577publication date2014-04-16
P1433published inCell ProliferationQ1952798
P1476titleInhibition enhancer of zeste homologue 2 promotes senescence and apoptosis induced by doxorubicin in p53 mutant gastric cancer cells
P478volume47

Reverse relations

cites work (P2860)
Q64118957Curcumin inhibits liver metastasis of gastric cancer through reducing circulating tumor cells
Q36237945DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis
Q50479840Developmental epigenetic programming of adult germ cell death disease: Polycomb protein EZH2-miR-101 pathway.
Q50115221EZH2 promotes hepatocellular carcinoma progression through modulating miR-22/galectin-9 axis
Q42365783EZH2-mediated repression of Dkk1 promotes hepatic stellate cell activation and hepatic fibrosis.
Q37392656EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma
Q55106988Epigenetic Contribution of High-Mobility Group A Proteins to Stem Cell Properties.
Q50324483Initial testing (stage 1) of tazemetostat (EPZ-6438), a novel EZH2 inhibitor, by the Pediatric Preclinical Testing Program
Q42178342MiR-330-3p inhibits gastric cancer progression through targeting MSI1.
Q46258700Naringin protects myocardial cells from doxorubicin‑induced apoptosis partially by inhibiting the p38MAPK pathway
Q36444065Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence
Q91704977Targeting epigenetics in sarcomas through EZH2 inhibition

Search more.