Cabozantinib for the treatment of renal cell carcinoma

scientific article published on 11 November 2016

Cabozantinib for the treatment of renal cell carcinoma is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1080/14656566.2016.1258059
P698PubMed publication ID27835047

P50authorLaurence AlbigesQ54553347
Bernard EscudierQ54553923
P2093author name stringJulie C Lougheed
P2860cites workCabozantinib overcomes crizotinib resistance in ROS1 fusion-positive cancerQ27853086
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Q27861047
Sunitinib versus interferon alfa in metastatic renal-cell carcinomaQ28282757
Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trialQ29615711
Pazopanib versus sunitinib in metastatic renal-cell carcinomaQ33409916
Impact of bone and liver metastases on patients with renal cell carcinoma treated with targeted therapyQ34007924
Cabozantinib in progressive medullary thyroid cancerQ34185084
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.Q34217927
Prognostic factors for survival in previously treated patients with metastatic renal cell carcinomaQ34293726
Cabozantinib versus Everolimus in Advanced Renal-Cell CarcinomaQ34495684
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial.Q34633525
Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trialQ34650664
Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma.Q34658095
The International Metastatic Renal Cell Carcinoma Database Consortium model as a prognostic tool in patients with metastatic renal cell carcinoma previously treated with first-line targeted therapy: a population-based studyQ35561464
c-Met is a prognostic marker and potential therapeutic target in clear cell renal cell carcinomaQ36551653
Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancerQ36822111
The VHL/HIF axis in clear cell renal carcinomaQ36872295
In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancerQ37403891
Targeted therapies for renal cell carcinoma: review of adverse event management strategiesQ37974894
A phase I study of cabozantinib (XL184) in patients with renal cell cancer.Q38430335
Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinomaQ38835745
Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial.Q38859789
Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growthQ39472261
Pharmacokinetic (PK) drug interaction studies of cabozantinib: Effect of CYP3A inducer rifampin and inhibitor ketoconazole on cabozantinib plasma PK and effect of cabozantinib on CYP2C8 probe substrate rosiglitazone plasma PK.Q41099660
Nivolumab versus Everolimus in Advanced Renal-Cell CarcinomaQ41316099
Differential expression of Axl and Gas6 in renal cell carcinoma reflecting tumor advancement and survival.Q45945576
Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites.Q45950959
Pharmacokinetics of cabozantinib tablet and capsule formulations in healthy adultsQ46252268
Independent assessment of lenvatinib plus everolimus in patients with metastatic renal cell carcinoma.Q52985746
Cabozantinib suppresses tumor growth and metastasis in hepatocellular carcinoma by a dual blockade of VEGFR2 and MET.Q54362470
Evaluation of the effect of food and gastric pH on the single-dose pharmacokinetics of cabozantinib in healthy adult subjects.Q55060584
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)2499-2504
P577publication date2016-11-11
P1433published inExpert Opinion on PharmacotherapyQ5421212
P1476titleCabozantinib for the treatment of renal cell carcinoma
P478volume17

Reverse relations

cites work (P2860)
Q57481747Cabozantinib for the Management of Metastatic Clear Cell Renal Cell Carcinoma
Q52661758Crosstalk between VEGFR and other receptor tyrosine kinases for TKI therapy of metastatic renal cell carcinoma.
Q49887893Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities

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