14-3-3 and β-catenin are secreted on extracellular vesicles to activate the oncogenic Wnt pathway

scientific article published on 22 March 2014

14-3-3 and β-catenin are secreted on extracellular vesicles to activate the oncogenic Wnt pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MOLONC.2014.03.011
P932PMC publication ID5528515
P698PubMed publication ID24721736

P2093author name stringAlona Zilberberg
Michal Caspi
Shiri Dovrat
Rina Rosin-Arbesfeld
Anastasia Firsow
Hila Gur
Lital Lahav
P2860cites workThe regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionQ21245733
LDL-receptor-related proteins in Wnt signal transductionQ24290392
Carboxypeptidase E: a negative regulator of the canonical Wnt signaling pathwayQ24294190
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Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylationQ24310980
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserineQ24322674
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Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complexQ24337717
Protein kinase A-mediated 14-3-3 association impedes human Dapper1 to promote dishevelled degradationQ24338245
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Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3Q24652985
B lymphocytes secrete antigen-presenting vesiclesQ24678522
The many faces and functions of β-cateninQ26865781
Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles.Q37420188
Proteomic analysis identifies that 14-3-3zeta interacts with beta-catenin and facilitates its activation by Akt.Q37593591
MYC and metastasisQ37853269
Structural basis of 14-3-3 protein functions.Q37932715
Overexpression of miR-126 inhibits the activation and migration of HSCs through targeting CRK.Q39028893
Dickkopf-1 inhibits thyroid cancer cell survival and migration through regulation of β-catenin/E-cadherin signalingQ39221932
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration.Q39222362
Active Wnt proteins are secreted on exosomes.Q39277713
A novel function of YWHAZ/β-catenin axis in promoting epithelial-mesenchymal transition and lung cancer metastasis.Q39293295
WNT11 Expression Is Induced by Estrogen-Related Receptor α and β-Catenin and Acts in an Autocrine Manner to Increase Cancer Cell MigrationQ39651531
Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerizationQ39715293
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.Q40036004
14-3-3Zeta does not increase GSK3beta-mediated tau phosphorylation in cell culture modelsQ40408040
14-3-3 binds to and mediates phosphorylation of microtubule-associated tau protein by Ser9-phosphorylated glycogen synthase kinase 3beta in the brainQ40568541
14-3-3 connects glycogen synthase kinase-3 beta to tau within a brain microtubule-associated tau phosphorylation complexQ40674756
Identification of the Axin and Frat binding region of glycogen synthase kinase-3.Q40768816
Follicular dendritic cells carry MHC class II-expressing microvesicles at their surfaceQ40867441
Chibby suppresses growth of human SW480 colon adenocarcinoma cells through inhibition of β-catenin signaling.Q41840666
LRRK2 secretion in exosomes is regulated by 14-3-3.Q42149865
Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarityQ43871029
Role of HMGB1 in proliferation and migration of human gingival and periodontal ligament fibroblastsQ46113056
14-3-3 epsilon modulates the stimulated secretion of endopeptidase 24.15.Q46386496
Endocytosis, intracellular sorting, and processing of exosomes by dendritic cellsQ80396444
Exosomes: a novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesionsQ27008452
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cellsQ27860717
Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.Q27967666
Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activityQ28114807
14-3-3 proteins--an updateQ28247242
Specificity and mechanism of action of some commonly used protein kinase inhibitorsQ28344791
The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entryQ28580062
Dynamic recruitment of axin by Dishevelled protein assembliesQ28592772
The structural basis for 14-3-3:phosphopeptide binding specificityQ29547190
Exosomes: composition, biogenesis and functionQ29547721
Proximal events in Wnt signal transductionQ29616162
14-3-3 proteins: structure, function, and regulationQ29619100
Wnt signalling and its impact on development and cancerQ29619273
Convergence of Wnt, beta-catenin, and cadherin pathwaysQ29619504
Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic diseaseQ30494070
Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand bindingQ31149686
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.Q33941102
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomesQ34156430
You Don't Muck with MYCQ34157211
Wnt signaling in cancerQ34262857
Three decades of Wnts: a personal perspective on how a scientific field developedQ34276643
Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors.Q34289010
14-3-3σ regulates β-catenin-mediated mouse embryonic stem cell proliferation by sequestering GSK-3β.Q34328767
Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signalingQ35005587
Drosophila S2 cells secrete wingless on exosome-like vesicles but the wingless gradient forms independently of exosomesQ35112325
Dishevelled C-terminus: prolyl and histidinyl motifsQ35148449
14-3-3 proteins as potential therapeutic targetsQ35510924
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activityQ35748395
Sphingolipid-modulated exosome secretion promotes clearance of amyloid-β by microgliaQ35879557
Endocytic control of growth factor signalling: multivesicular bodies as signalling organellesQ36029933
Oncogenicity of the developmental transcription factor Sox9.Q36043468
SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genesQ36322037
14-3-3σ stabilizes a complex of soluble actin and intermediate filament to enable breast tumor invasionQ37236386
FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stressQ37267966
The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer developmentQ37332559
Reflecting on 25 years with MYC.Q37333643
P4510describes a project that usesImageJQ1659584
P433issue5
P921main subjectextracellular vesicleQ21097485
P304page(s)894-911
P577publication date2014-03-22
P1433published inMolecular OncologyQ2190736
P1476title14-3-3 and β-catenin are secreted on extracellular vesicles to activate the oncogenic Wnt pathway
P478volume8

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