scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1080/13543776.2017.1261111 |
P698 | PubMed publication ID | 27841045 |
P50 | author | Kunal Nepali | Q89110255 |
Ritu Ojha | Q99741360 | ||
P2093 | author name string | Sahil Sharma | |
Jagjeet Singh | |||
Harbinder Singh | |||
Anu Ojha | |||
P2860 | cites work | 2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia | Q24612292 |
Deciphering the inhibitory mechanism of genistein on xanthine oxidase in vitro. | Q53420327 | ||
Design and synthesis of novel 2-(indol-5-yl)thiazole derivatives as xanthine oxidase inhibitors. | Q53600813 | ||
Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors. | Q54373597 | ||
Initiation of allopurinol at first medical contact for acute attacks of gout: a randomized clinical trial. | Q55056789 | ||
Structure and Function of Xanthine Oxidoreductase | Q55982356 | ||
The influence of electronic, steric and hydrophobic properties of flavonoid compounds in the inhibition of the xanthine oxidase | Q58318980 | ||
Synthesis and xanthine oxidase inhibitory activity of 7-methyl-2-(phenoxymethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one derivatives | Q59140340 | ||
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol | Q24652967 | ||
Mechanistic insights into xanthine oxidoreductase from development studies of candidate drugs to treat hyperuricemia and gout | Q27023909 | ||
An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition | Q27639928 | ||
X-ray crystal structure of a xanthine oxidase complex with the flavonoid inhibitor quercetin | Q27694616 | ||
Urate-lowering therapy for gout: focus on febuxostat | Q28283310 | ||
Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase | Q28481361 | ||
A practical approach to gout. Current management of an 'old' disease | Q33758862 | ||
How is gout managed in primary care? A review of current practice and proposed guidelines | Q33884300 | ||
Gout update: from lab to the clinic and back | Q33914121 | ||
Prevention and Management of Gout | Q34305913 | ||
Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers | Q34455863 | ||
Progress towards the discovery of xanthine oxidase inhibitors. | Q34541602 | ||
Febuxostat compared with allopurinol in patients with hyperuricemia and gout | Q34563183 | ||
Effect of food or antacid on pharmacokinetics and pharmacodynamics of febuxostat in healthy subjects | Q34584089 | ||
Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout | Q34737229 | ||
A benefit-risk assessment of benzbromarone in the treatment of gout. Was its withdrawal from the market in the best interest of patients? | Q34797671 | ||
Isolation and synthesis of biologically active carbazole alkaloids | Q34995236 | ||
Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers | Q36535526 | ||
2012 American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis | Q36870924 | ||
Molecular hybridization: a useful tool in the design of new drug prototypes | Q36879306 | ||
3,4-Dihydroxy-5-nitrobenzaldehyde (DHNB) is a potent inhibitor of xanthine oxidase: a potential therapeutic agent for treatment of hyperuricemia and gout | Q37277498 | ||
The treatment of hyperuricemia | Q38576552 | ||
Development of 2-(Substituted Benzylamino)-4-Methyl-1, 3-Thiazole-5-Carboxylic Acid Derivatives as Xanthine Oxidase Inhibitors and Free Radical Scavengers. | Q40314317 | ||
Population Pharmacokinetics and Therapeutic Efficacy of Febuxostat in Patients with Severe Renal Impairment. | Q40727676 | ||
Severe allopurinol toxicity. Description and guidelines for prevention in patients with renal insufficiency | Q40830127 | ||
Febuxostat inhibition of endothelial-bound XO: implications for targeting vascular ROS production | Q42127578 | ||
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia. | Q42714465 | ||
A comparative study of AutoDock and PMF scoring performances, and SAR of 2-substituted pyrazolotriazolopyrimidines and 4-substituted pyrazolopyrimidines as potent xanthine oxidase inhibitors | Q43206017 | ||
Insights into the inhibition of xanthine oxidase by curcumin | Q43267657 | ||
2-Alkyloxyalkylthiohypoxanthines as new potent inhibitors of xanthine oxidase | Q43838644 | ||
Molecular modeling of flavonoids that inhibits xanthine oxidase | Q44021036 | ||
The reaction mechanism of xanthine oxidase: evidence for two-electron chemistry rather than sequential one-electron steps | Q44238301 | ||
Binding of xanthine oxidase to glycosaminoglycans limits inhibition by oxypurinol | Q44962055 | ||
Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers | Q45167605 | ||
Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial | Q46271681 | ||
The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase | Q46477429 | ||
6-(N-benzoylamino)purine as a novel and potent inhibitor of xanthine oxidase: inhibition mechanism and molecular modeling studies | Q46737383 | ||
Identification of a potent xanthine oxidase inhibitor from oxidation of caffeic acid | Q46935245 | ||
Does starting allopurinol prolong acute treated gout? A randomized clinical trial | Q48089305 | ||
Quick identification of xanthine oxidase inhibitor and antioxidant from Erycibe obtusifolia by a drug discovery platform composed of multiple mass spectrometric platforms and thin-layer chromatography bioautography. | Q51076921 | ||
Synthesis and evaluation of 1-hydroxy/methoxy-4-methyl-2-phenyl-1H-imidazole-5-carboxylic acid derivatives as non-purine xanthine oxidase inhibitors. | Q51722188 | ||
Hypouricemic effect of allopurinol and the novel xanthine oxidase inhibitor TEI-6720 in chimpanzees. | Q52846892 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | xanthine oxidase inhibitor | Q8042974 |
P304 | page(s) | 311-345 | |
P577 | publication date | 2016-11-12 | |
P1433 | published in | Expert Opinion on Therapeutic Patents | Q5421213 |
P1476 | title | An updated patent review: xanthine oxidase inhibitors for the treatment of hyperuricemia and gout (2011-2015). | |
P478 | volume | 27 |