Functional Transformation of C-reactive Protein by Hydrogen Peroxide

scientific article published on 17 January 2017

Functional Transformation of C-reactive Protein by Hydrogen Peroxide is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M116.773176
P932PMC publication ID5336149
P698PubMed publication ID28096464

P2093author name stringSanjay K Singh
Alok Agrawal
Avinash Thirumalai
Asmita Pathak
Donald N Ngwa
P2860cites workC-reactive protein-bound enzymatically modified low-density lipoprotein does not transform macrophages into foam cellsQ24321501
Human L-ficolin recognizes phosphocholine moieties of pneumococcal teichoic acidQ27695732
A staggered decameric assembly of human C-reactive protein stabilized by zinc ions revealed by X-ray crystallographyQ27697272
Three dimensional structure of human C-reactive proteinQ27732605
C-reactive protein is essential for innate resistance to pneumococcal infectionQ33842663
Cell signaling by reactive nitrogen and oxygen species in atherosclerosisQ34006311
C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipidsQ34191416
Identification of acidic pH-dependent ligands of pentameric C-reactive proteinQ34285524
Obesity associated molecular forms of C-reactive protein in humanQ34316624
Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent mannerQ34620560
Atherosclerosis-Related Functions of C-Reactive ProteinQ35073552
C-reactive protein protects mice against pneumococcal infection via both phosphocholine-dependent and phosphocholine-independent mechanismsQ35439657
An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair modeQ35671242
Exposing a hidden functional site of C-reactive protein by site-directed mutagenesisQ35728529
Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cellsQ35818866
Human C-reactive protein slows atherosclerosis development in a mouse model with human-like hypercholesterolemiaQ35963030
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.Q35979041
Studies of acute phase protein. I. An immunohistochemical method for the localization of Cx-reactive protein in rabbits. Association with necrosis in local inflammatory lesionsQ36334412
Low density lipoprotein and very low density lipoprotein are selectively bound by aggregated C-reactive proteinQ36346658
The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholineQ36423484
Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injuryQ36732994
C-reactive protein/oxidised low-density lipoprotein/β2-glycoprotein I complex promotes atherosclerosis in diabetic BALB/c mice via p38mitogen-activated protein kinase signal pathwayQ36814928
Y402H polymorphism of complement factor H affects binding affinity to C-reactive proteinQ36860930
An Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive ProteinQ36884724
Redox regulation in the extracellular environmentQ37045097
Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro.Q37067700
Interaction of calcium-bound C-reactive protein with fibronectin is controlled by pH: in vivo implicationsQ37285802
The vicious circle between oxidative stress and inflammation in atherosclerosis.Q37334949
The binding of C-reactive protein, in the presence of phosphoethanolamine, to low-density lipoproteins is due to phosphoethanolamine-generated acidic pH.Q37416223
Roles of oxidative stress and redox regulation in atherosclerosisQ37596240
Recognition functions of pentameric C-reactive protein in cardiovascular diseaseQ38221846
Probing the C1q-binding site on human C-reactive protein by site-directed mutagenesisQ38307556
Collagen-induced arthritis is exacerbated in C-reactive protein-deficient miceQ38341672
C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significanceQ38596519
The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation.Q38863991
A conformational change of C-reactive protein in burn wounds unmasks its proinflammatory propertiesQ38993371
Sustained submicromolar H2O2 levels induce hepcidin via signal transducer and activator of transcription 3 (STAT3).Q39288648
Pathophysiological condition changes the conformation of a flexible FBG-related protein, switching it from pathogen-recognition to host-interactionQ39521307
Factor H-related protein 5 interacts with pentraxin 3 and the extracellular matrix and modulates complement activationQ40161972
The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cellsQ40172276
Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding proteinQ40271737
Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen PeroxideQ40699809
Interaction of C-reactive protein with artificial phosphatidylcholine bilayersQ41752082
Effect of CRP on Some of the in vitro Physicochemical Properties of LDLQ41971745
C-reactive protein exists in an NaCl concentration-dependent pentamer-decamer equilibrium in physiological bufferQ41986528
Complement factor H binds to denatured rather than to native pentameric C-reactive proteinQ42043743
Macrophage uptake of low-density lipoprotein bound to aggregated C-reactive protein: possible mechanism of foam-cell formation in atherosclerotic lesionsQ43002113
Gain of function of immunoglobulins after partial unfolding or cofactor bindingQ44212984
Lectin specificity and binding characteristics of human C-reactive proteinQ44393824
Possible protective role for C-reactive protein in atherogenesis: complement activation by modified lipoproteins halts before detrimental terminal sequenceQ44810016
C-reactive protein inhibits in vitro oxidation of low-density lipoprotein.Q44923160
Defined chemically cross-linked oligomers of human C-reactive protein: characterization and reactivity with the complement systemQ45118568
Monomeric C-reactive protein decreases acetylated LDL uptake in human endothelial cellsQ46243550
Role of C-reactive protein in atherogenesis: can the apolipoprotein E knockout mouse provide the answer?Q46513399
Effect of modified C-reactive protein on complement activation: a possible complement regulatory role of modified or monomeric C-reactive protein in atherosclerotic lesionsQ46925904
ATP modulates acute inflammation in vivo through dual oxidase 1-derived H2O2 production and NF-κB activation.Q47074216
C-reactive protein-like immunoreactivity in the neurofibrillary tangles of Alzheimer's diseaseQ48796828
Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy.Q51070812
A redox switch in C-reactive protein modulates activation of endothelial cells.Q51595729
Cell membranes and liposomes dissociate C-reactive protein (CRP) to form a new, biologically active structural intermediate: mCRP(m).Q51717888
Studies on the interactions between C-reactive protein and complement proteins.Q52576446
Native C-reactive protein increases whereas modified C-reactive protein reduces atherosclerosis in apolipoprotein E-knockout mice.Q53662602
C-reactive protein specifically enhances platelet-activating factor-induced inflammatory activity in vivo.Q53676541
Specificity of C-reactive protein for choline phosphate residues of pneumococcal C-polysaccharide.Q53895846
Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic PlaquesQ57132361
Localizing of C-reactive protein in synovium of patients with rheumatoid arthritisQ67708757
Modulation of stimulus-dependent human platelet activation by C-reactive protein modified with active oxygen speciesQ68415994
Complement activation induced by human C-reactive protein in mildly acidic conditionsQ68843776
Immunohistochemical studies of C-reactive protein and apolipoprotein B in inflammatory and arterial lesionsQ69886670
Localization of C-reactive protein in inflammatory lesions of experimental allergic encephalomyelitisQ70181304
Purification and characterization of human serum C-reactive proteinQ71145528
Binding of model soluble immune complexes to modified C-reactive proteinQ71151738
Binding of fibronectin by the acute phase reactant C-reactive proteinQ71260800
Comparative analyses of pentraxins: implications for protomer assembly and ligand bindingQ72609807
Complement and atherogenesis: binding of CRP to degraded, nonoxidized LDL enhances complement activationQ73083027
Calcium-dependent and -independent binding of the pentraxin serum amyloid P component to glycosaminoglycans and amyloid proteins: enhanced binding at slightly acid pHQ73370299
C-reactive protein in the arterial intima: role of C-reactive protein receptor-dependent monocyte recruitment in atherogenesisQ74290879
Evidence of hypoxic areas within the arterial wall in vivoQ77297609
Expression of rabbit C-reactive protein in transgenic mice inhibits development of antigen-induced arthritisQ79297270
Structural and functional comparison of native pentameric, denatured monomeric and biotinylated C-reactive proteinQ79428361
Conduct unbecoming: C-reactive protein interactions with a broad range of protein moleculesQ80572759
Interactions of C-reactive protein with low-density lipoproteins: implications for an active role of modified C-reactive protein in atherosclerosisQ82075603
Modified C-reactive protein interacts with platelet glycoprotein IbαQ84165501
Immunohistochemical staining reveals C-reactive protein existing predominantly as altered conformation forms in inflammatory lesionsQ85261573
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)3129-3136
P577publication date2017-01-17
P1433published inJournal of Biological ChemistryQ867727
P1476titleFunctional Transformation of C-reactive Protein by Hydrogen Peroxide
P478volume292

Reverse relations

cites work (P2860)
Q90441319C-Reactive Protein and Its Structural Isoforms: An Evolutionary Conserved Marker and Central Player in Inflammatory Diseases and Beyond
Q54957842C-Reactive Protein as a Therapeutic Target in Age-Related Macular Degeneration.
Q54946647C-Reactive Protein in Atherothrombosis and Angiogenesis.
Q64078741Evolution of C-Reactive Protein
Q92405017Functionality of C-Reactive Protein for Atheroprotection
Q64092597Hyper-acidic fusion minipeptides escort the intrinsic antioxidative ability of the pattern recognition receptor CRP in non-animal organisms
Q46284091Redox-Sensitive Innate Immune Pathways During Macrophage Activation in Type 1 Diabetes
Q64100462Structure-Function Relationships of C-Reactive Protein in Bacterial Infection
Q92445757The Multiple Faces of C-Reactive Protein-Physiological and Pathophysiological Implications in Cardiovascular Disease
Q92116745Zinc-α2-glycoprotein as an inhibitor of amine oxidase copper-containing 3

Search more.