Myelofibrosis: to transplant or not to transplant?

scientific article published on December 2016

Myelofibrosis: to transplant or not to transplant? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1182/ASHEDUCATION-2016.1.543
P932PMC publication ID6142493
P698PubMed publication ID27913527

P2093author name stringVikas Gupta
Rebecca Devlin
P2860cites workSomatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2Q24568313
Hematopoietic Cell Transplantation as Curative Therapy for Patients with Myelofibrosis: Long-Term Success in all Age GroupsQ26786893
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Correlation of mutation profile and response in patients with myelofibrosis treated with ruxolitinibQ27853179
CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisonsQ29998841
Splenectomy in myelofibrosis with myeloid metaplasia: a single-institution experience with 223 patients.Q33331903
Refined cytogenetic-risk categorization for overall and leukemia-free survival in primary myelofibrosis: a single center study of 433 patientsQ33392291
Allogeneic haematopoietic stem cell transplantation for myelofibrosis: a report of the Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC).Q33393151
DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion statusQ33393245
JAK inhibition with ruxolitinib versus best available therapy for myelofibrosisQ33399977
Splenectomy and hemopoietic stem cell transplantation for myelofibrosisQ73709920
Hematopoietic cell transplantation as curative therapy for idiopathic myelofibrosis, advanced polycythemia vera, and essential thrombocythemiaQ79817900
Different outcome of allogeneic transplantation in myelofibrosis using conventional or reduced-intensity conditioning regimensQ80262366
A retrospective comparison of conventional intensity conditioning and reduced-intensity conditioning for allogeneic hematopoietic cell transplantation in myelofibrosisQ83388958
The outcome of allo-HSCT for 92 patients with myelofibrosis in the Nordic countriesQ84065231
Splenectomy after allogeneic haematopoietic stem cell transplantation in patients with primary myelofibrosisQ84552610
SRSF2 mutations in primary myelofibrosis: significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survivalQ84962229
Activity of therapeutic JAK 1/2 blockade in graft-versus-host diseaseQ87635679
A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosisQ33399980
Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosisQ33411211
Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosisQ33416223
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Allogeneic transplantation for primary myelofibrosis with BM, peripheral blood or umbilical cord blood: an analysis of the JSHCTQ33556843
Allogeneic hematopoietic stem cell transplantation in patients with polycythemia vera or essential thrombocythemia transformed to myelofibrosis or acute myeloid leukemia: a report from the MPN Subcommittee of the Chronic Malignancies Working Party oQ33558748
Measurement and impact of comorbidity in older cancer patientsQ34014917
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Somatic mutations of calreticulin in myeloproliferative neoplasmsQ34039270
MPD-RC 101 prospective study of reduced-intensity allogeneic hematopoietic stem cell transplantation in patients with myelofibrosisQ34047897
Impact of allogeneic stem cell transplantation on survival of patients less than 65 years of age with primary myelofibrosis.Q35634902
The Dynamic International Prognostic Scoring System for myelofibrosis predicts outcomes after hematopoietic cell transplantationQ35849342
Allogeneic hematopoietic stem cell transplantation for myelofibrosisQ36385798
A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase III trials of ruxolitinib for the treatment of myelofibrosisQ36708975
Effects of spleen status on early outcomes after hematopoietic cell transplantationQ36712192
Outcomes of Allogeneic Hematopoietic Cell Transplantation in Patients with Myelofibrosis with Prior Exposure to Janus Kinase 1/2 Inhibitors.Q37272164
Reduced-intensity hematopoietic cell transplantation for patients with primary myelofibrosis: a cohort analysis from the center for international blood and marrow transplant research.Q37457111
Allogeneic hematopoietic cell transplantation for myelofibrosis in the era of JAK inhibitorsQ38018908
Safety and Efficacy of Fedratinib in Patients With Primary or Secondary Myelofibrosis: A Randomized Clinical TrialQ38407900
Indication and management of allogeneic stem cell transplantation in primary myelofibrosis: a consensus process by an EBMT/ELN international working groupQ38570614
Incidence and risk factors of poor graft function after allogeneic stem cell transplantation for myelofibrosisQ38879870
The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosisQ40625383
Pharmacologic Inhibition of JAK1/JAK2 Signaling Reduces Experimental Murine Acute GVHD While Preserving GVT EffectsQ40936847
Changes in quality of life and disease-related symptoms in patients with polycythemia vera receiving ruxolitinib or standard therapyQ41095829
JAK inhibition induces silencing of T Helper cytokine secretion and a profound reduction in T regulatory cellsQ41160178
Improved Outcome of Alternative Donor Transplantations in Patients with Myelofibrosis: From Unrelated to Haploidentical Family Donors.Q41235146
Effect of conditioning regimens on graft failure in myelofibrosis: a retrospective analysisQ41519713
Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow TransplantationQ43265365
Allogeneic hematopoietic stem cell transplantation in myelofibrosis: the 20-year experience of the Gruppo Italiano Trapianto di Midollo Osseo (GITMO).Q44707716
Treatment outcomes following leukemic transformation in Philadelphia-negative myeloproliferative neoplasms.Q45905329
Allogeneic hemopoietic SCT for patients with primary myelofibrosis: a predictive transplant score based on transfusion requirement, spleen size and donor typeQ47174502
Allogeneic hematopoietic cell transplantation for myelofibrosis in patients pretreated with the JAK1 and JAK2 inhibitor ruxolitinib.Q53099028
Leukemia risk models in primary myelofibrosis: an International Working Group study.Q53136481
Risk models predicting survival after reduced-intensity transplantation for myelofibrosis.Q53136705
Outcome after Transplantation According to Reduced-Intensity Conditioning Regimen in Patients Undergoing Transplantation for Myelofibrosis.Q53198934
Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms.Q54225327
Development of extramedullary sites of leukaemia during ruxolitinib therapy for myelofibrosis.Q54349909
Type 1 vs type 2 calreticulin mutations in primary myelofibrosis: differences in phenotype and prognostic impact.Q54374932
JAK inhibition with ruxolitinib as pretreatment for allogeneic stem cell transplantation in primary or post-ET/PV myelofibrosis.Q54374933
EZH2 mutational status predicts poor survival in myelofibrosis.Q54560112
The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: an international study of 797 patientsQ58455624
Allogeneic hematopoietic cell transplantation for myelofibrosis using fludarabine-, intravenous busulfan- and low-dose TBI-based conditioningQ60710884
Incidence and Risk Factors for Early Hepatotoxicity and Its Impact on Survival in Patients with Myelofibrosis Undergoing Allogeneic Hematopoietic Cell TransplantationQ60710980
P433issue1
P921main subjectmyelofibrosisQ1752571
P304page(s)543-551
P577publication date2016-12-01
P1433published inHematology / the Education Program of the American Society of HematologyQ26842068
P1476titleMyelofibrosis: to transplant or not to transplant?
P478volume2016

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cites work (P2860)
Q91893832Determinants of survival in myelofibrosis patients undergoing allogeneic hematopoietic cell transplantation
Q89777328Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy
Q90547544Management of myelofibrosis after ruxolitinib failure
Q39027848Mutations in MPNs: prognostic implications, window to biology, and impact on treatment decisions
Q90064075Patterns of Ruxolitinib Therapy Failure and Its Management in Myelofibrosis: Perspectives of the Canadian Myeloproliferative Neoplasm Group

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