Cumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment

scientific article published on 19 November 2016

Cumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.IJHEH.2016.11.007
P932PMC publication ID5401775
P698PubMed publication ID27923611

P2093author name stringKembra L Howdeshell
L Earl Gray
Andrew K Hotchkiss
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Dose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in RatsQ36363691
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Something from "nothing"--eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effectsQ43982052
The combined effects of vinclozolin and procymidone do not deviate from expected additivity in vitro and in vivoQ44300353
Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHP.Q44630870
A mixture of the "antiandrogens" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashionQ44860302
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Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genesQ44869977
A mixture of seven antiandrogens induces reproductive malformations in ratsQ44872672
Detection of phthalate metabolites in human amniotic fluidQ45054875
Critical window of male reproductive tract development in rats following gestational exposure to di-n-butyl phthalateQ46344137
Urinary metabolites of di-n-octyl phthalate in ratsQ46445681
Brominated flame retardants and organochlorine pollutants in aquatic and terrestrial predatory birds of Belgium: levels, patterns, tissue distribution and condition factors.Q46590837
A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive mannerQ46645636
Environmental monitoring and ecological risk assessment for pesticide contamination and effects in Lake Pamvotis, northwestern Greece.Q46664967
Urinary and amniotic fluid levels of phthalate monoesters in rats after the oral administration of di(2-ethylhexyl) phthalate and di-n-butyl phthalateQ46711070
Temporal variability in urinary concentrations of phthalate metabolites, phytoestrogens and phenols among minority children in the United StatesQ46919544
Measurement of eight urinary metabolites of di(2-ethylhexyl) phthalate as biomarkers for human exposure assessmentQ46949311
Mixtures of endocrine-disrupting contaminants induce adverse developmental effects in preweaning rats.Q50705519
Late-life effects on rat reproductive system after developmental exposure to mixtures of endocrine disrupters.Q50706378
Phthalate exposure in pregnant women and newborns - the urinary metabolite excretion pattern differs distinctly.Q50755077
Human biomonitoring of phthalate exposure in Austrian children and adults and cumulative risk assessment.Q50921239
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Identification of potential biomarkers of exposure to di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH), an alternative for phthalate plasticizers.Q51367452
Occurrence of pharmaceuticals and personal care products and associated environmental risks in the central and lower Yangtze river, China.Q51444442
Urinary and serum metabolites of di-n-pentyl phthalate in ratsQ51537300
Urinary metabolites of diisodecyl phthalate in rats.Q51753407
Dysgenesis and histological changes of genitals and perturbations of gene expression in male rats after in utero exposure to antiandrogen mixtures.Q51917755
Environmental hormone disruptors: evidence that vinclozolin developmental toxicity is mediated by antiandrogenic metabolites.Q52216206
Endocrine disruption in wildlife: a critical review of the evidence.Q52531570
Estimated daily intake and cumulative risk assessment of phthalate diesters in a Belgian general population.Q52651400
Organochlorine pesticides, lead, and mercury in northern bobwhite (Colinus virginianus) and scaled quail (Callipepla squamata) from the Rolling Plains ecoregion of Texas and Oklahoma.Q52791648
Repeating history: pharmaceuticals in the environment.Q55047753
Effects of procymidone on reproductive organs and serum gonadotropins in male ratsQ72832141
Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestationQ73731578
P433issue2 Pt A
P921main subjecthealth risk assessmentQ2284929
P304page(s)179-188
P577publication date2016-11-19
P1433published inInternational Journal of Hygiene and Environmental HealthQ15758318
P1476titleCumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment
P478volume220

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cites work (P2860)
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Q89263246Mixed "Antiandrogenic" Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat
Q55404689Overview of air pollution and endocrine disorders.
Q60105954Perinatal exposure to an environmentally relevant mixture of phthalates results in a lower number of neurons and synapses in the medial prefrontal cortex and decreased cognitive flexibility in adult male and female rats
Q40050576Personal Care Product Use in Men and Urinary Concentrations of Select Phthalate Metabolites and Parabens: Results from the Environment And Reproductive Health (EARTH) Study
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