| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Raúl Rabadán | Q7296181 |
| P2093 | author name string | Daniel I S Rosenbloom | |
| Pablo G Camara | |||
| Tim Chu | |||
| P2860 | cites work | Evolutionary dynamics of cancer in response to targeted combination therapy | Q21128788 |
| Inferring clonal composition from multiple sections of a breast cancer | Q21145293 | ||
| Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer | Q22001096 | ||
| Fitness and its role in evolutionary genetics | Q22122004 | ||
| Cancer as an evolutionary and ecological process | Q22122026 | ||
| Cancer genome landscapes | Q22242276 | ||
| The genomics of organismal diversification illuminated by adaptive radiations | Q35741729 | ||
| Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence | Q35746363 | ||
| Subclonal diversification of primary breast cancer revealed by multiregion sequencing | Q35847434 | ||
| Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells | Q35863199 | ||
| Outwitting evolution: fighting drug-resistant TB, malaria, and HIV. | Q35878689 | ||
| Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis | Q35952716 | ||
| FISHtrees 3.0: Tumor Phylogenetics Using a Ploidy Probe | Q36064765 | ||
| A Big Bang model of human colorectal tumor growth | Q36074227 | ||
| Drug concentration heterogeneity facilitates the evolution of drug resistance. | Q36312295 | ||
| Improving Cancer Treatment via Mathematical Modeling: Surmounting the Challenges Is Worth the Effort | Q36364933 | ||
| Mutations of Bacteria from Virus Sensitivity to Virus Resistance | Q24533278 | ||
| Ernst Mayr: Genetics and speciation | Q24545703 | ||
| Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq | Q24598443 | ||
| Intratumor heterogeneity: evolution through space and time | Q24598678 | ||
| Genome-wide detection of single-nucleotide and copy-number variations of a single human cell | Q24602999 | ||
| Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer | Q24604601 | ||
| International network of cancer genome projects | Q24611474 | ||
| Distant metastasis occurs late during the genetic evolution of pancreatic cancer | Q24624284 | ||
| Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells | Q24630239 | ||
| Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 | Q24651548 | ||
| Cytokines in cancer drug resistance: Cues to new therapeutic strategies | Q26753299 | ||
| Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response | Q26785914 | ||
| Environmentally induced epigenetic transgenerational inheritance of phenotype and disease | Q26830773 | ||
| Intratumoral heterogeneity: Clonal cooperation in epithelial-to-mesenchymal transition and metastasis | Q26991480 | ||
| Cancer evolution: mathematical models and computational inference | Q27002537 | ||
| Molecular mechanisms of epithelial-mesenchymal transition | Q27013743 | ||
| Single-cell RNA-seq: advances and future challenges | Q27023759 | ||
| CellTree: an R/bioconductor package to infer the hierarchical structure of cell populations from single-cell RNA-seq data | Q27318663 | ||
| SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution | Q27321859 | ||
| A potent combination of the novel PI3K Inhibitor, GDC-0941, with imatinib in gastrointestinal stromal tumor xenografts: long-lasting responses after treatment withdrawal | Q27851995 | ||
| Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner. | Q28115436 | ||
| mRNA-Seq whole-transcriptome analysis of a single cell | Q28240611 | ||
| Tumor heterogeneity: biological implications and therapeutic consequences | Q28270935 | ||
| Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines | Q28483475 | ||
| Tumour evolution inferred by single-cell sequencing | Q28646966 | ||
| The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers | Q29395525 | ||
| Clonal evolution in cancer | Q29547696 | ||
| Inferring phylogeny despite incomplete lineage sorting | Q29614322 | ||
| Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma | Q29615604 | ||
| The causes and consequences of genetic heterogeneity in cancer evolution | Q29615848 | ||
| Intra-tumour heterogeneity: a looking glass for cancer? | Q29620149 | ||
| Evolutionary dynamics of HIV at multiple spatial and temporal scales. | Q30416280 | ||
| Tumors as organs: complex tissues that interface with the entire organism | Q30495528 | ||
| Survival improvement by decade of patients aged 0-14 years with acute lymphoblastic leukemia: a SEER analysis | Q30572783 | ||
| PurBayes: estimating tumor cellularity and subclonality in next-generation sequencing data | Q30643738 | ||
| qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles | Q34438482 | ||
| Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth | Q34457728 | ||
| Biological and therapeutic impact of intratumor heterogeneity in cancer evolution | Q34457994 | ||
| Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells | Q34502783 | ||
| Genetic clonal diversity predicts progression to esophageal adenocarcinoma | Q34505745 | ||
| Timing and heterogeneity of mutations associated with drug resistance in metastatic cancers | Q34525966 | ||
| Hybrid models of tumor growth. | Q34676158 | ||
| In vivo switching of human melanoma cells between proliferative and invasive states | Q34745037 | ||
| Deep sequencing of multiple regions of glial tumors reveals spatial heterogeneity for mutations in clinically relevant genes | Q34746613 | ||
| Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics | Q34753191 | ||
| Adaptive therapy. | Q34984307 | ||
| Smart-seq2 for sensitive full-length transcriptome profiling in single cells. | Q34993864 | ||
| Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients | Q35063579 | ||
| Heterogeneity for IGF-II production maintained by public goods dynamics in neuroendocrine pancreatic cancer | Q35089999 | ||
| Endothelial signaling during development | Q35141786 | ||
| The mutant selection window and antimicrobial resistance | Q35153856 | ||
| SNES: single nucleus exome sequencing | Q35216503 | ||
| Paracrine SDF-1α signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells | Q35550177 | ||
| Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma | Q35596369 | ||
| Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment | Q35607837 | ||
| Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells | Q35623336 | ||
| Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance | Q35699612 | ||
| TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data | Q30838548 | ||
| CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data | Q31122354 | ||
| Visualization and analysis of single-cell RNA-seq data by kernel-based similarity learning | Q31171256 | ||
| Adaptation and diversification on islands | Q33408531 | ||
| PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data | Q33511182 | ||
| Adaptive radiation, ecological opportunity, and evolutionary determinism. American Society of Naturalists E. O. Wilson award address | Q33562006 | ||
| Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype | Q33604942 | ||
| The role of genetic diversity in cancer | Q33604953 | ||
| Tumor heterogeneity: causes and consequences | Q33624298 | ||
| Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer | Q33667666 | ||
| Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing | Q33701811 | ||
| High-definition reconstruction of clonal composition in cancer | Q33775654 | ||
| Mutation and selection in bacterial populations: alternatives to the hypothesis of directed mutation | Q33850651 | ||
| Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing | Q33881155 | ||
| The evolution of mutation rates: separating causes from consequences | Q33925698 | ||
| EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing | Q34016908 | ||
| Clonal evolution in breast cancer revealed by single nucleus genome sequencing. | Q34041603 | ||
| Single-cell genome sequencing: current state of the science | Q34045945 | ||
| The tumor microenvironment as a determinant of cancer cell survival: a possible mechanism for de novo drug resistance | Q34086152 | ||
| Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis | Q34111187 | ||
| A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors | Q34132936 | ||
| Allele-specific copy number analysis of tumors | Q34165640 | ||
| Principles for the buffering of genetic variation | Q34171380 | ||
| Tumor heterogeneity | Q34257678 | ||
| Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor | Q34258285 | ||
| Absolute quantification of somatic DNA alterations in human cancer | Q34271693 | ||
| Accumulation of driver and passenger mutations during tumor progression | Q34276850 | ||
| Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity | Q34287934 | ||
| CEL-Seq: single-cell RNA-Seq by multiplexed linear amplification | Q34297012 | ||
| Sex combs find middle ground in evolution debate | Q34314322 | ||
| Robustness of cellular functions | Q34348549 | ||
| PyClone: statistical inference of clonal population structure in cancer. | Q34410309 | ||
| A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma | Q34418880 | ||
| Antiretroviral dynamics determines HIV evolution and predicts therapy outcome | Q36374300 | ||
| Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells | Q36374588 | ||
| Tumor microenvironment and drug resistance in hematologic malignancies | Q36571508 | ||
| Evolution and impact of subclonal mutations in chronic lymphocytic leukemia | Q36619124 | ||
| Stochastic or deterministic: what is the effective population size of HIV-1? | Q36627391 | ||
| Tumor Heterogeneity--A 'Contemporary Concept' Founded on Historical Insights and Predictions | Q36636235 | ||
| Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. | Q36673354 | ||
| Mutant selection window hypothesis updated. | Q36728061 | ||
| KIT over-expression by p55PIK-PI3K leads to Imatinib-resistance in patients with gastrointestinal stromal tumors | Q36738831 | ||
| Unifying principles of regeneration I: Epimorphosis versus morphallaxis. | Q36750165 | ||
| Phylogenetic analysis of multiple FISH markers in oral tongue squamous cell carcinoma suggests that a diverse distribution of copy number changes is associated with poor prognosis | Q36774411 | ||
| Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma | Q36796606 | ||
| Sequential, alternating, and maintenance/consolidation chemotherapy in advanced non-small cell lung cancer: a review of the literature | Q36807152 | ||
| Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma. | Q36855805 | ||
| Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity | Q36917711 | ||
| Milestones in the curability of pediatric cancers | Q36925083 | ||
| Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition | Q36925503 | ||
| Regulation of in situ to invasive breast carcinoma transition | Q36995611 | ||
| Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq | Q37094024 | ||
| Tumor microenvironmental signaling elicits epithelial-mesenchymal plasticity through cooperation with transforming genetic events | Q37162410 | ||
| Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance | Q37178380 | ||
| Cell motility and drug gradients in the emergence of resistance to chemotherapy | Q37218419 | ||
| Heterogeneity of kinase inhibitor resistance mechanisms in GIST | Q37218711 | ||
| Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma. | Q37279893 | ||
| Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia | Q37322911 | ||
| Evolutionary theory of cancer | Q37536213 | ||
| Genetic and phenotypic diversity in breast tumor metastases | Q37659374 | ||
| TGFbeta signalling: a complex web in cancer progression | Q37760038 | ||
| Cellular interactions in metastasis | Q37956445 | ||
| Mechanisms of acquired resistance to targeted cancer therapies. | Q38034816 | ||
| Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end? | Q38062793 | ||
| The implications of clonal genome evolution for cancer medicine | Q38085043 | ||
| Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review | Q38109551 | ||
| Biomarkers for dysplastic Barrett's: ready for prime time? | Q38213141 | ||
| Computational and analytical challenges in single-cell transcriptomics | Q38335021 | ||
| Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms | Q38543385 | ||
| Tumorigenesis: it takes a village | Q38544200 | ||
| The mathematics of cancer: integrating quantitative models | Q38644551 | ||
| An epigenetic gateway to brain tumor cell identity | Q38682159 | ||
| Mechanisms of tumor cell resistance to the current targeted-therapy agents. | Q38828353 | ||
| A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity | Q38843089 | ||
| Clonal cooperativity in heterogenous cancers | Q38943125 | ||
| Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm | Q39386631 | ||
| Multiple instances of ancient balancing selection shared between humans and chimpanzees | Q39444727 | ||
| A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer | Q39593316 | ||
| Clonal evolution of glioblastoma under therapy. | Q39704836 | ||
| Mutations driving CLL and their evolution in progression and relapse | Q39714436 | ||
| Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia | Q39841048 | ||
| SNES makes sense? Single-cell exome sequencing evolves | Q40080232 | ||
| Identification of neutral tumor evolution across cancer types. | Q40093976 | ||
| A theoretical quantitative model for evolution of cancer chemotherapy resistance | Q40516956 | ||
| PhyloWGS: reconstructing subclonal composition and evolution from whole-genome sequencing of tumors | Q41197854 | ||
| Expression and function of Fas (APO-1/CD95) in patient myeloma cells and myeloma cell lines. | Q41335349 | ||
| The effect of one additional driver mutation on tumor progression. | Q41846748 | ||
| The first five years of single-cell cancer genomics and beyond | Q41890682 | ||
| A framework for understanding and targeting residual disease in oncogene-driven solid cancers | Q41908997 | ||
| Dynamics of targeted cancer therapy | Q42197906 | ||
| Extensions of the coalescent effective population size | Q43203442 | ||
| Morphallaxis in an aquatic oligochaete, Lumbriculus variegatus: reorganization of escape reflexes in regenerating body fragments | Q43624675 | ||
| Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing | Q46302330 | ||
| Tumor heterogeneity is fundamental to the tumor ecosystem | Q46838384 | ||
| The cultural evolution of emergent group-level traits | Q47629496 | ||
| Seven great achievements in pediatric research in the past 40 y. | Q48097968 | ||
| Combination of Imatinib Mesylate and AKT Inhibitor Provides Synergistic Effects in Preclinical Study of Gastrointestinal Stromal Tumor | Q48644058 | ||
| Evolution of worker policing. | Q50225511 | ||
| A robustness-based approach to systems-oriented drug design. | Q51062307 | ||
| Lessons from applied ecology: cancer control using an evolutionary double bind. | Q51178741 | ||
| Kicking Genomic Profiling to the Curb: How Re-wiring the Phosphoproteome Can Explain Treatment Resistance in Glioma. | Q51374811 | ||
| A change of strategy in the war on cancer. | Q51826240 | ||
| Plasticity in the nervous system of adult hydra. III. Conversion of neurons to expression of a vasopressin-like immunoreactivity depends on axial location. | Q52236269 | ||
| The genetic origin of drug resistance in neoplasms: implications for systemic therapy. | Q52688528 | ||
| Phosphoinositide 3-kinase inhibitors combined with imatinib in patient-derived xenograft models of gastrointestinal stromal tumors: rationale and efficacy. | Q53011276 | ||
| PI3K/AKT/mTOR pathway is activated after imatinib secondary resistance in gastrointestinal stromal tumors (GISTs). | Q53583519 | ||
| Cancer therapy: an evolved approach. | Q53790106 | ||
| Rationale for the use of alternating non-cross-resistant chemotherapy. | Q54520436 | ||
| Adaptive radiation in a heterogeneous environment | Q56038387 | ||
| Mutational Pathway Determines Whether Drug Gradients Accelerate Evolution of Drug-Resistant Cells | Q59444106 | ||
| Improved outcome in childhood acute lymphoblastic leukaemia with reinforced early treatment and rotational combination chemotherapy | Q68289938 | ||
| Central nervous system therapy and combination chemotherapy of childhood lymphocytic leukemia | Q68620531 | ||
| Nine years' experience with "total therapy" of childhood acute lymphocytic leukemia | Q69000391 | ||
| Molecular phylogenetic perspective on evolution of lizards of the Anolis grahami series | Q77879780 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | ecosystem | Q37813 |
| P304 | page(s) | 69-83 | |
| P577 | publication date | 2016-12-05 | |
| P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
| P1476 | title | Evolutionary scalpels for dissecting tumor ecosystems | |
| P478 | volume | 1867 |
| Q92914470 | An analysis of genetic heterogeneity in untreated cancers |
| Q39328610 | Modeling the process of human tumorigenesis. |
| Q52715807 | The Role for Myc in Coordinating Glycolysis, Oxidative Phosphorylation, Glutaminolysis, and Fatty Acid Metabolism in Normal and Neoplastic Tissues. |
| Q89866606 | Tumour heterogeneity and the evolutionary trade-offs of cancer |
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