scholarly article | Q13442814 |
P50 | author | Jean-Charles Grivel | Q50223411 |
P2093 | author name string | Margolis LB | |
P2860 | cites work | Infection of human tonsil histocultures: a model for HIV pathogenesis | Q34289423 |
In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression. | Q34445208 | ||
CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue | Q34838416 | ||
The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes | Q36028490 | ||
Evidence for the HIV-1 phenotype switch as a causal factor in acquired immunodeficiency. | Q39025427 | ||
Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: implications for HIV primary infection | Q39621505 | ||
CCR5 promoter polymorphism and HIV-1 disease progression. Multicenter AIDS Cohort Study (MACS). | Q44433174 | ||
Experimental HIV infection of human lymphoid tissue: correlation of CD4+ T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histocultures inoculated with laboratory strains and patient isolates of HIV type 1. | Q45763843 | ||
Association between biological properties of human immunodeficiency virus variants and risk for AIDS and AIDS mortality | Q45844635 | ||
Quantitative image analysis of HIV-1 infection in lymphoid tissue | Q49118200 | ||
Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4. | Q55067967 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | lymphoid tissue | Q3529455 |
P304 | page(s) | 344-346 | |
P577 | publication date | 1999-03-01 | |
P1433 | published in | Nature Medicine | Q1633234 |
P1476 | title | CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue | |
P478 | volume | 5 |
Q35828692 | Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. |
Q40771766 | Anti-HIV activity of a novel aminoglycoside-arginine conjugate |
Q40567871 | Apoptosis of bystander T cells induced by human immunodeficiency virus type 1 with increased envelope/receptor affinity and coreceptor binding site exposure |
Q24801374 | Apoptosis of uninfected cells induced by HIV envelope glycoproteins |
Q34008699 | Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS. |
Q21245460 | Asymmetric HIV-1 co-receptor use and replication in CD4(+) T lymphocytes |
Q39808350 | Biological signature characteristics of primary isolates from human immunodeficiency virus type 1 group O in ex vivo human tonsil histocultures. |
Q35847699 | CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis |
Q46200257 | CD4+ T-cell loss and delayed expression of modulators of immune responses at mucosal sites of vaccinated macaques following SIV(mac251) infection |
Q38945956 | CXCR4 tropic human immunodeficiency virus type 1 induces an apoptotic cascade in immature infected thymocytes that resembles thymocyte negative selection |
Q22251080 | Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection |
Q39389448 | Cellular specificity of HIV-1 replication can be controlled by LTR sequences. |
Q35252587 | Cervico-vaginal tissue ex vivo as a model to study early events in HIV-1 infection |
Q37409937 | Comparison of human immunodeficiency virus type 1 tropism profiles in clinical samples by the Trofile and MT-2 assays |
Q33700312 | Contrasting roles for TLR ligands in HIV-1 pathogenesis |
Q33788810 | Cryptic nature of a conserved, CD4-inducible V3 loop neutralization epitope in the native envelope glycoprotein oligomer of CCR5-restricted, but not CXCR4-using, primary human immunodeficiency virus type 1 strains |
Q77890057 | Cytokine modulation of HIV-1 chemokine receptor expression |
Q35020604 | Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression |
Q39604766 | Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression |
Q33854835 | Cytopathicity of human immunodeficiency virus type 1 primary isolates depends on coreceptor usage and not patient disease status |
Q61312704 | Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1 |
Q39600315 | Detection of CXCR4 receptors on cell surface using a fluorescent metal nanoshell |
Q33930335 | Differential pathogenesis of primary CCR5-using human immunodeficiency virus type 1 isolates in ex vivo human lymphoid tissue |
Q33459192 | Differential role of autophagy in CD4 T cells and macrophages during X4 and R5 HIV-1 infection |
Q58291165 | Does cyclosporin A affect CCR5 and CXCR4 expression in primary HIV-1-infected patients? |
Q39597678 | Dynamics of CCR5 expression by CD4(+) T cells in lymphoid tissues during simian immunodeficiency virus infection |
Q45068171 | Effect of a CCR5 inhibitor on viral loads in macaques dual-infected with R5 and X4 primate immunodeficiency viruses |
Q37365672 | Emergence and persistence of CXCR4-tropic HIV-1 in a population of men from the multicenter AIDS cohort study |
Q43480510 | Enhanced CD4+ cellular apoptosis by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with progressive HIV-1 infection |
Q34602799 | Expression of HIV receptors, alternate receptors and co-receptors on tonsillar epithelium: implications for HIV binding and primary oral infection |
Q57081259 | Extracellular vesicles generated by placental tissues ex vivo: A transport system for immune mediators and growth factors |
Q38671045 | Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1. |
Q61807035 | HIV Impacts CD34 Progenitors Involved in T-Cell Differentiation During Coculture With Mouse Stromal OP9-DL1 Cells |
Q39830948 | HIV integrase and the swan song of the CD4 T cells? |
Q95817407 | HIV-1 entry inhibitors: evading the issue |
Q34510531 | HIV-1 expressing the envelopes of transmitted/founder or control/reference viruses have similar infection patterns of CD4 T-cells in human cervical tissue ex vivo |
Q36384710 | HIV-1 induced activation of CD4+ T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo |
Q35897398 | HIV-1 vaginal transmission: cell-free or cell-associated virus? |
Q37194757 | High frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections |
Q37483781 | Highly pathogenic SHIVs and SIVs target different CD4+ T cell subsets in rhesus monkeys, explaining their divergent clinical courses |
Q52639187 | Histoculture and Infection with HIV of Functional Human Lymphoid Tissue on Gelfoam®. |
Q43921996 | Human Herpesvirus 6 immediate-early 1 protein is a sumoylated nuclear phosphoprotein colocalizing with promyelocytic leukemia protein-associated nuclear bodies |
Q34341001 | Human immunodeficiency virus pathogenesis: insights from studies of lymphoid cells and tissues |
Q33848419 | Human immunodeficiency virus type 1 (HIV-1) non-B subtypes are similar to HIV-1 subtype B in that coreceptor specificity is a determinant of cytopathicity in human lymphoid tissue infected ex vivo |
Q33787161 | Human immunodeficiency virus type 1 coreceptor preferences determine target T-cell depletion and cellular tropism in human lymphoid tissue |
Q33810879 | Human immunodeficiency virus type 1 induces apoptosis in CD4(+) but not in CD8(+) T cells in ex vivo-infected human lymphoid tissue |
Q33283061 | Identification of a CCR5-expressing T cell subset that is resistant to R5-tropic HIV infection |
Q34349528 | Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 binding |
Q34342452 | Impact of cytokines on replication in the thymus of primary human immunodeficiency virus type 1 isolates from infants |
Q35015256 | In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline |
Q40584611 | In vivo evolution of X4 human immunodeficiency virus type 1 variants in the natural course of infection coincides with decreasing sensitivity to CXCR4 antagonists |
Q34977020 | In vivo evolution of human immunodeficiency virus type 1 toward increased pathogenicity through CXCR4-mediated killing of uninfected CD4 T cells |
Q36958820 | Induction of simian AIDS in infant rhesus macaques infected with CCR5- or CXCR4-utilizing simian-human immunodeficiency viruses is associated with distinct lesions of the thymus |
Q35635009 | Inhibition of human immunodeficiency virus envelope glycoprotein- mediated single cell lysis by low-molecular-weight antagonists of viral entry |
Q36315592 | Interactions between human immunodeficiency virus type 1 and vaccinia virus in human lymphoid tissue ex vivo |
Q34781801 | Interleukin-7-dependent production of RANTES that correlates with human immunodeficiency virus disease progression |
Q35115692 | Lentiviral Nef proteins manipulate T cells in a subset-specific manner |
Q35939279 | Macroautophagy Regulation during HIV-1 Infection of CD4+ T Cells and Macrophages |
Q34226885 | Macrophage-tropic simian/human immunodeficiency virus chimeras use CXCR4, not CCR5, for infections of rhesus macaque peripheral blood mononuclear cells and alveolar macrophages |
Q53421778 | Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis. |
Q37410434 | Multisite comparison of anti-human immunodeficiency virus microbicide activity in explant assays using a novel endpoint analysis |
Q34075705 | M‐tropic HIV envelope protein gp120 exhibits a different neuropathological profile than T‐tropic gp120 in rat striatum |
Q34437067 | Noninfectious X4 but not R5 human immunodeficiency virus type 1 virions inhibit humoral immune responses in human lymphoid tissue ex vivo |
Q36458354 | Oral CCR5 inhibitors: will they make it through? |
Q35155259 | Pathogenic effects of human herpesvirus 6 in human lymphoid tissue ex vivo |
Q89594106 | Persistent immune activation in HIV-1 infected ex vivo model tissues subjected to antiretroviral therapy: Soluble and extracellular vesicle-associated cytokines |
Q33858164 | Preferential coreceptor utilization and cytopathicity by dual-tropic HIV-1 in human lymphoid tissue ex vivo. |
Q39682314 | Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo |
Q35953364 | Proteolytic processing of human serum albumin generates EPI-X4, an endogenous antagonist of CXCR4. |
Q33650466 | R5 strains of human immunodeficiency virus type 1 from rapid progressors lacking X4 strains do not possess X4-type pathogenicity in human thymus. |
Q34990608 | Real-time PCR assay of individual human immunodeficiency virus type 1 variants in coinfected human lymphoid tissues |
Q40901418 | Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection |
Q38879644 | Replicative fitness of CCR5-using and CXCR4-using human immunodeficiency virus type 1 biological clones |
Q33404066 | Selective transmission of R5 HIV-1 over X4 HIV-1 at the dendritic cell-T cell infectious synapse is determined by the T cell activation state |
Q35018140 | Selective transmission of R5 HIV-1 variants: where is the gatekeeper? |
Q31440420 | Small molecule inhibitor of HIV-1 nuclear import suppresses HIV-1 replication in human lymphoid tissue ex vivo: a potential addition to current anti-HIV drug repertoire. |
Q46162481 | The effect of progesterone levels and pregnancy on HIV-1 coreceptor expression |
Q34430862 | The mucosal immune system: primary target for HIV infection and AIDS. |
Q40384920 | The role of upstream U3 sequences in HIV-1 replication and CD4+ T cell depletion in human lymphoid tissue ex vivo |
Q35826002 | Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. |
Q39031676 | Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome |
Q34066122 | Urokinase-urokinase receptor interaction mediates an inhibitory signal for HIV-1 replication |
Q34566597 | Use of human mucosal tissue to study HIV-1 pathogenesis and evaluate HIV-1 prevention modalities |
Q36189818 | Use of human tissue explants to study human infectious agents |
Q24524292 | Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease |
Q33933260 | Viral exploitation and subversion of the immune system through chemokine mimicry |
Q35635030 | Viral interactions in human lymphoid tissue: Human herpesvirus 7 suppresses the replication of CCR5-tropic human immunodeficiency virus type 1 via CD4 modulation |
Q57008354 | Virus phenotype switching and disease progression in HIV-1 infection |
Q37596639 | Vpr and Vpu are important for efficient human immunodeficiency virus type 1 replication and CD4+ T-cell depletion in human lymphoid tissue ex vivo |
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