Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges

scientific article published on January 2017

Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/CMR.00058-16
P932PMC publication ID5217799
P698PubMed publication ID27974412

P50authorRobert A BonomoQ62516257
Travis B NielsenQ91989803
P2093author name stringBrad Spellberg
Paul Pantapalangkoor
Darren Wong
Brian Luna
P2860cites workBeta lactam antibiotic monotherapy versus beta lactam-aminoglycoside antibiotic combination therapy for sepsisQ24201201
Bacteremia caused by Acinetobacter ursingiiQ24550977
Signature motifs identify an Acinetobacter Cif virulence factor with epoxide hydrolase activityQ24568297
Reservoirs of Non-baumannii Acinetobacter SpeciesQ26766441
Pathogenic Acinetobacter: from the Cell Surface to Infinity and BeyondQ26771783
Acinetobacter infection--an emerging threat to human healthQ26861494
Combination therapies for combating antimicrobial resistanceQ27015710
Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to calprotectin-mediated zinc sequestrationQ27339544
Microbial synergy via an ethanol-triggered pathwayQ27938765
Transferrin-mediated iron sequestration as a novel therapy for bacterial and fungal infectionsQ28084708
Acinetobacter in modern warfareQ28263145
Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumanniiQ36035894
Acinetobacter baumannii Genes Required for Bacterial Survival during Bloodstream Infection.Q36052630
Toll-Like Receptor 9 Contributes to Defense against Acinetobacter baumannii Infection.Q36053482
Global challenge of multidrug-resistant Acinetobacter baumanniiQ36095081
Acinetobacter spp. are associated with a higher mortality in intensive care patients with bacteremia: a survival analysis.Q36099594
Excess deaths associated with tigecycline after approval based on noninferiority trialsQ36115632
Epidemiologic and clinical impact of Acinetobacter baumannii colonization and infection: a reappraisalQ36150941
Combination therapy for treatment of infections with gram-negative bacteriaQ36156077
Antibiotic trends of Klebsiella pneumoniae and Acinetobacter baumannii resistance indicators in an intensive care unit of Southern Italy, 2008-2013Q36246604
Clinical impact and pathogenicity of Acinetobacter.Q36282248
Neutrophils play an important role in host resistance to respiratory infection with Acinetobacter baumannii in miceQ36314004
Joint Transcriptional Control of Virulence and Resistance to Antibiotic and Environmental Stress in Acinetobacter baumannii.Q36318967
The epidemiology and control of Acinetobacter baumannii in health care facilitiesQ36382140
Infrequent air contamination with Acinetobacter baumannii of air surrounding known colonized or infected patientsQ36390792
Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosisQ36457770
Distribution of Acinetobacter species on human skin: comparison of phenotypic and genotypic identification methodsQ36547397
Parenteral and inhaled colistin for treatment of ventilator-associated pneumoniaQ36559388
Acinetobacter baumannii rOmpA vaccine dose alters immune polarization and immunodominant epitopesQ36569183
Acinetobacter baumannii Is Dependent on the Type II Secretion System and Its Substrate LipA for Lipid Utilization and In Vivo FitnessQ36575078
Is inhaled colistin beneficial in ventilator associated pneumonia or nosocomial pneumonia caused by Acinetobacter baumannii?Q36611906
Implications of endotracheal tube biofilm in ventilator-associated pneumonia response: a state of conceptQ36633627
The importance of colonization pressure in multiresistant Acinetobacter baumannii acquisition in a Greek intensive care unitQ36633704
The K1 capsular polysaccharide from Acinetobacter baumannii is a potential therapeutic target via passive immunization.Q36646787
Acinetobacter seifertii Isolated from China: Genomic Sequence and Molecular Epidemiology Analyses.Q36664024
Porins, efflux pumps and multidrug resistance in Acinetobacter baumannii.Q36746061
Trauma-related infections in battlefield casualties from IraqQ36800879
Rat pneumonia and soft-tissue infection models for the study of Acinetobacter baumannii biologyQ36804312
The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific MannerQ36849931
White paper: recommendations on the conduct of superiority and organism-specific clinical trials of antibacterial agents for the treatment of infections caused by drug-resistant bacterial pathogensQ36854025
Intraspecies Transfer of the Chromosomal Acinetobacter baumannii blaNDM-1 Carbapenemase GeneQ36887836
Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii.Q36887978
Community-acquired Acinetobacter infectionsQ36911392
Outer membrane Protein A plays a role in pathogenesis of Acinetobacter nosocomialisQ36913254
Colistin inhalation monotherapy for ventilator-associated pneumonia of Acinetobacter baumannii in prematurityQ46581461
Prevalence of metallo-beta lactamase (MBL) producing Pseudomonas spp. and Acinetobacter spp. in a tertiary care hospital in IndiaQ46742865
Clinical efficacy and safety of the combination of colistin plus vancomycin for the treatment of severe infections caused by carbapenem-resistant Acinetobacter baumanniiQ46939760
Distribution of the blaOXA-23-containing transposons Tn2006 and Tn2008 in Australian carbapenem-resistant Acinetobacter baumannii isolatesQ47938576
Complete sequence of the bla(NDM-1)-carrying plasmid pNDM-AB from Acinetobacter baumannii of food animal originQ48040631
Quinolone-resistance mutations in the topoisomerase IV parC gene of Acinetobacter baumanniiQ48048984
Recovery of multidrug-resistant bacteria from combat personnel evacuated from Iraq and Afghanistan at a single military treatment facilityQ49138790
Antimicrobial resistance among Gram-negative bacilli isolated from Latin America: results from SENTRY Antimicrobial Surveillance Program (Latin America, 2008-2010).Q50940090
Nebulized colistin in the treatment of pneumonia due to multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.Q51379524
Structure-function relationships of CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii.Q51554133
Clinical and microbiological characterization of carbapenem-resistant Acinetobacter baumannii bloodstream infections.Q51733097
K19 capsular polysaccharide of Acinetobacter baumannii is produced via a Wzy polymerase encoded in a small genomic island rather than the KL19 capsule gene cluster.Q53078312
Efficacy of high-dose nebulized colistin in ventilator-associated pneumonia caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii.Q53121080
CpaA a novel protease from Acinetobacter baumannii clinical isolates deregulates blood coagulation.Q53530929
Structure of repeating unit of the capsular polysaccharide from Acinetobacter baumannii D78 and assignment of the K4 gene cluster.Q53973487
Isolation of Acinetobacter spp. including A. baumannii from vegetables: implications for hospital-acquired infections.Q54083016
IMP-1-producing carbapenem-resistant Acinetobacter ursingii from Japan.Q54303551
Molecular characterisation of multiple drug-resistant Acinetobacter baumannii isolates in southern Taiwan.Q54351983
High endemic levels of multidrug-resistant Acinetobacter baumannii among hospitals in southern Brazil.Q54357839
A global virulence regulator in Acinetobacter baumannii and its control of the phenylacetic acid catabolic pathway.Q54384104
Building a benchmark through active surveillance of intensive care unit-acquired infections: the Italian network SPIN-UTIQ59447730
Differential Roles of CD14 and Toll-like Receptors 4and 2 in MurineAcinetobacterPneumoniaQ62516238
The Acute‐Phase Response and Serum Amyloid A Inhibit the Inflammatory Response toAcinetobacter baumanniiPneumoniaQ62516241
Seasonal variation of Acinetobacter infections: 1987-1996. Nosocomial Infections Surveillance SystemQ64131324
Acinetobacter species: which do we mean?Q67571571
Outer membrane permeability of Acinetobacter calcoaceticus and its implication in antibiotic resistanceQ67708324
Infections due to organisms of the genus Herellea. B5W and B. anitratumQ76473847
The United States Food and Drug Administration and the end of antibioticsQ77440626
Differences in Acinetobacter baumannii strains and host innate immune response determine morbidity and mortality in experimental pneumoniaQ34162588
Stress response and virulence functions of the Acinetobacter baumannii NfuA Fe-S scaffold proteinQ34216622
Channel formation by CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumanniiQ34228361
Comparison of the virulence potential of Acinetobacter strains from clinical and environmental sourcesQ34288902
Role of macrophages in early host resistance to respiratory Acinetobacter baumannii infectionQ34328536
A fatal case of multidrug resistant acinetobacter necrotizing fasciitis: the changing scary face of nosocomial infectionQ34366502
Acinetobacter baumannii infections among patients at military medical facilities treating injured U.S. service members, 2002-2004.Q34368824
Carbapenem-hydrolyzing GES-type extended-spectrum beta-lactamase in Acinetobacter baumanniiQ34483646
Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosaQ34555131
Acinetobacter baumannii lipopolysaccharides are potent stimulators of human monocyte activation via Toll-like receptor 4 signalling.Q34574281
An outbreak of multidrug-resistant Acinetobacter baumannii-calcoaceticus complex infection in the US military health care system associated with military operations in Iraq.Q34579696
Evaluation of clonality and carbapenem resistance mechanisms among Acinetobacter baumannii-Acinetobacter calcoaceticus complex and Enterobacteriaceae isolates collected in European and Mediterranean countries and detection of two novel β-lactamases,Q34597608
Two cases of necrotizing fasciitis due to Acinetobacter baumanniiQ34598764
Immunization with lipopolysaccharide-deficient whole cells provides protective immunity in an experimental mouse model of Acinetobacter baumannii infectionQ34653632
Gram-negative infections in adult intensive care units of latin america and the CaribbeanQ34695842
A Review of Novel Combinations of Colistin and Lipopeptide or Glycopeptide Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii.Q34726120
Impaired virulence and in vivo fitness of colistin-resistant Acinetobacter baumannii.Q34764355
Virulence-related traits of epidemic Acinetobacter baumannii strains belonging to the international clonal lineages I-III and to the emerging genotypes ST25 and ST78Q34779353
Acinetobacter baumannii: emergence of a successful pathogenQ34795807
Causes of infection after earthquake, China, 2008.Q34908091
Detection of the KPC gene in Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii during a PCR-based nosocomial surveillance study in Puerto RicoQ35005198
Carbapenem-resistant Acinetobacter baumannii from Brazil: role of carO alleles expression and blaOXA-23 geneQ35032793
Effectiveness of tigecycline-based versus colistin- based therapy for treatment of pneumonia caused by multidrug-resistant Acinetobacter baumannii in a critical setting: a matched cohort analysisQ35101242
Antibiotic modulation of capsular exopolysaccharide and virulence in Acinetobacter baumanniiQ35101682
Use of a new mouse model of Acinetobacter baumannii pneumonia to evaluate the postantibiotic effect of imipenemQ35132306
Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factorsQ35134033
Acinetobacter baumannii RecA protein in repair of DNA damage, antimicrobial resistance, general stress response, and virulenceQ35139132
Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistanceQ35139329
Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia modelQ35168859
Dissemination of blaOXA-23 in Acinetobacter spp. in China: main roles of conjugative plasmid pAZJ221 and transposon Tn2009Q35168950
In vitro activity of RX-P873 against Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumanniiQ35169078
Role of the carboxy terminus of SecA in iron acquisition, protein translocation, and virulence of the bacterial pathogen Acinetobacter baumanniiQ35187576
Impact of Acinetobacter baumannii superoxide dismutase on motility, virulence, oxidative stress resistance and susceptibility to antibioticsQ35202480
Do antibiotic combinations prevent the emergence of resistant organisms?Q39527576
Effect of desiccation on the ultrastructural appearances of Acinetobacter baumannii and Acinetobacter lwoffiiQ39603231
The prevention of biofilm colonization by multidrug-resistant pathogens that cause ventilator-associated pneumonia with antimicrobial-coated endotracheal tubesQ39786245
Survival of Acinetobacter baumannii on dry surfacesQ40013606
Acinetobacter baumannii outer membrane protein A targets the nucleus and induces cytotoxicity.Q40087259
Laboratory diagnosis, clinical management and infection control of the infections caused by extensively drug-resistant Gram-negative bacilli: a Chinese consensus statementQ40252535
A case of necrotizing fasciitis with septic shock in a cat caused by Acinetobacter baumanniiQ40434847
Studies on Pneumococcus Variation: I. Variants Characterized by Rapid Lysis and Absence of Normal Growth under the Routine Method of Cultivation.Q40574376
Predictors of mortality in patients with extensively drug-resistant Acinetobacter baumannii pneumonia receiving colistin therapy.Q40611400
Multidrug resistance, inappropriate empiric therapy, and hospital mortality in Acinetobacter baumannii pneumonia and sepsisQ40612894
Genetic environment of the KPC gene in Acinetobacter baumannii ST2 clone from Puerto Rico and genomic insights into its drug resistanceQ40646501
Acinetobacter baumannii and A. pittii clinical isolates lack adherence and cytotoxicity to lung epithelial cells in vitroQ40655676
Minocycline activity tested against Acinetobacter baumannii complex, Stenotrophomonas maltophilia, and Burkholderia cepacia species complex isolates from a global surveillance program (2013).Q40700100
OmpW is a potential target for eliciting protective immunity against Acinetobacter baumannii infectionsQ40700556
Pharmacodynamic evaluation of extending the administration time of meropenem using a Monte Carlo simulationQ40732203
The first cases of human bacteremia caused by Acinetobacter seifertii in JapanQ40829471
Bloodstream infection caused by extensively drug-resistant Acinetobacter baumannii in cancer patients: high mortality associated with delayed treatment rather than with the degree of neutropeniaQ40854491
Nosocomial Acinetobacter pneumonia: Treatment and prognostic factors in 356 casesQ40883429
Immunoprotective potential of in silico predicted Acinetobacter baumannii outer membrane nuclease, NucAbQ40892025
Infections with Acinetobacter calcoaceticus (Herellea vaginicola): clinical and laboratory studiesQ40892705
Geographical patterns in antimicrobial resistance of acinetobacter in clinical isolatesQ40933983
Secular trends in Acinetobacter baumannii resistance in respiratory and blood stream specimens in the United States, 2003 to 2012: A survey studyQ41008459
Loss of LPS is involved in the virulence and resistance to colistin of colistin-resistant Acinetobacter nosocomialis mutants selected in vitroQ41031269
Immunological evaluation of OMV(PagL)+Bap(1-487aa) and AbOmpA(8-346aa)+Bap(1-487aa) as vaccine candidates against Acinetobacter baumannii sepsis infectionQ41050257
Optimisation of the Caenorhabditis elegans model for studying the pathogenesis of opportunistic Acinetobacter baumannii.Q41089013
Risk factors for and impact of carbapenem-resistant Acinetobacter baumannii colonization and infection: matched case-control studyQ41092223
Fatal outbreak of an emerging clone of extensively drug-resistant Acinetobacter baumannii with enhanced virulence.Q41138033
Emergence of colistin resistance without loss of fitness and virulence after prolonged colistin administration in a patient with extensively drug-resistant Acinetobacter baumannii.Q41348499
Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumanniiQ41364861
Excess Mortality Associated With Colistin-Tigecycline Compared With Colistin-Carbapenem Combination Therapy for Extensively Drug-Resistant Acinetobacter baumannii Bacteremia: A Multicenter Prospective Observational StudyQ41403170
Acinetobacter nosocomialis secretes outer membrane vesicles that induce epithelial cell death and host inflammatory responsesQ41427005
Antimicrobial efficacy of doripenem and its combinations with sulbactam, amikacin, colistin, tigecycline in experimental sepsis of carbapenem-resistant Acinetobacter baumanniiQ41448443
Extrahuman epidemiology of Acinetobacter baumannii in Lebanon.Q41524681
A 4-year prospective study to determine the incidence and microbial etiology of surgical site infections at a private tertiary care hospital in Mumbai, IndiaQ41560142
Molecular mechanisms of sulbactam antibacterial activity and resistance determinants in Acinetobacter baumannii.Q41561999
Acinetobacter baumannii universal stress protein A plays a pivotal role in stress response and is essential for pneumonia and sepsis pathogenesis.Q41623346
Ability of bacteriophage in resolving wound infection caused by multidrug-resistant Acinetobacter baumannii in uncontrolled diabetic ratsQ41654959
Description of the OXA-23 β-lactamase gene located within Tn2007 in a clinical isolate of Acinetobacter baumannii from SpainQ41668012
Bad bugs need old drugs: a stewardship program's evaluation of minocycline for multidrug-resistant Acinetobacter baumannii infectionsQ41676559
Genetic Manipulation of Acinetobacter baumanniiQ41678791
Antibiotic resistance and phylogenetic characterization of Acinetobacter baumannii strains isolated from commercial raw meat in SwitzerlandQ41680011
Pathogenicity of clinical Acinetobacter baumannii isolates in a Galleria mellonella host model according to bla(OXA-40) gene and epidemiological outbreak statusQ41907650
Globally expanding carbapenemase finally appears in Spain: nosocomial outbreak of acinetobacter baumannii producing plasmid-encoded OXA-23 in Barcelona, SpainQ41918992
Patterns of nosocomial infections, multidrug-resistant microorganisms, and mold detection after extensive black-water flooding: a survey from central ThailandQ41968461
Microbiologic characteristics of pathogenic bacteria from hospitalized trauma patients who survived Wenchuan earthquakeQ41974103
Retention of virulence following adaptation to colistin in Acinetobacter baumannii reflects the mechanism of resistance.Q41998459
Microbiologic study of the pathogens isolated from wound culture among Wenchuan earthquake survivorsQ41998725
Acinetobacter baumannii virulence is enhanced in Galleria mellonella following biofilm adaptationQ42014835
The long-distance tertiary air transfer and care of tsunami victims: injury pattern and microbiological and psychological aspectsQ42025143
Galleria mellonella as a model system to study Acinetobacter baumannii pathogenesis and therapeuticsQ42025783
Multidrug-resistant Acinetobacter baumannii in veterinary clinics, GermanyQ42037228
Hospital-acquired infections following the 1999 Marmara earthquakeQ42041112
Antibacterial activities of iron chelators against common nosocomial pathogensQ42075825
CarbAcineto NP test for rapid detection of carbapenemase-producing Acinetobacter spp.Q42100476
AbuO, a TolC-like outer membrane protein of Acinetobacter baumannii, is involved in antimicrobial and oxidative stress resistanceQ42132845
Clinical features and epidemiology of Acinetobacter baumannii colonization and infection in Spanish hospitalsQ42167294
Spread of a carbapenem- and colistin-resistant Acinetobacter baumannii ST2 clonal strain causing outbreaks in two Sicilian hospitalsQ42221541
Comparison of colistin-carbapenem, colistin-sulbactam, and colistin plus other antibacterial agents for the treatment of extremely drug-resistant Acinetobacter baumannii bloodstream infections.Q42228164
Risk factors and outcome analysis of acinetobacter baumannii complex bacteremia in critical patientsQ42234026
Prevalence of carbapenem-hydrolyzing class D β-lactamase genes in Acinetobacter spp. isolates in China.Q42234875
Epidemiology of bloodstream infections caused by Acinetobacter baumannii and impact of drug resistance to both carbapenems and ampicillin-sulbactam on clinical outcomesQ42245284
The K1 capsular polysaccharide of Acinetobacter baumannii strain 307-0294 is a major virulence factorQ42428390
The deadly impact of extreme drug resistance in Acinetobacter baumanniiQ42575612
Bacteriology of war wounds at the time of injuryQ42600453
Safety and efficacy of intravenous tigecycline in subjects with secondary bacteremia: pooled results from 8 phase III clinical trialsQ42643577
The Response of Acinetobacter baumannii to Zinc Starvation.Q42735239
Emergence of tigecycline & colistin resistant Acinetobacter baumanii in patients with complicated urinary tract infections in north IndiaQ42758854
A difficult case of necrotizing fasciitis caused by Acinetobacter baumanniiQ42785229
Identification and characterization of a glycosyltransferase involved in Acinetobacter baumannii lipopolysaccharide core biosynthesisQ28274696
Fatal case of multi-drug resistant Acinetobacter baumannii necrotizing fasciitisQ28286321
Effect of ethanol on differential protein production and expression of potential virulence functions in the opportunistic pathogen Acinetobacter baumanniiQ28392232
Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infectionQ28478751
The Acinetobacter baumannii entA gene located outside the acinetobactin cluster is critical for siderophore production, iron acquisition and virulenceQ28483237
Identification of a general O-linked protein glycosylation system in Acinetobacter baumannii and its role in virulence and biofilm formationQ28484155
Loss of mitochondrial protein Fus1 augments host resistance to Acinetobacter baumannii infectionQ28504978
Differential Role of the T6SS in Acinetobacter baumannii VirulenceQ28548409
Comparable Efficacy of Tigecycline versus Colistin Therapy for Multidrug-Resistant and Extensively Drug-Resistant Acinetobacter baumannii Pneumonia in Critically Ill PatientsQ28550492
Medically Relevant Acinetobacter Species Require a Type II Secretion System and Specific Membrane-Associated Chaperones for the Export of Multiple Substrates and Full VirulenceQ28552441
Alternatives to antibiotics—a pipeline portfolio reviewQ29365161
Acquisition of resistance to carbapenems in multidrug-resistant clinical strains of Acinetobacter baumannii: natural insertional inactivation of a gene encoding a member of a novel family of beta-barrel outer membrane proteinsQ30160281
Bacterial identification, clinical significance, and antimicrobial susceptibilities of Acinetobacter ursingii and Acinetobacter schindleri, two frequently misidentified opportunistic pathogensQ30499245
Emergence of extensively drug-resistant Acinetobacter baumannii complex over 10 years: nationwide data from the Taiwan Surveillance of Antimicrobial Resistance (TSAR) programQ30559669
Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010.Q30580647
Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii.Q30761262
Acinetobacter seifertii sp. nov., a member of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex isolated from human clinical specimensQ30882972
Rapid dissemination of colistin and carbapenem resistant Acinetobacter baumannii in Central Greece: mechanisms of resistance, molecular identification and epidemiological data.Q31031386
Identification of an OprD homologue in Acinetobacter baumanniiQ33228855
Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesisQ33535645
Vaccines for Acinetobacter baumannii: thinking "out of the box".Q33637895
The battle for iron between bacterial pathogens and their vertebrate hostsQ33658687
Detection of KPC in Acinetobacter spp. in Puerto RicoQ33676198
AB5075, a Highly Virulent Isolate of Acinetobacter baumannii, as a Model Strain for the Evaluation of Pathogenesis and Antimicrobial Treatments.Q33709547
Genome-wide identification of Acinetobacter baumannii genes necessary for persistence in the lungQ33724918
Nutritional immunity beyond iron: a role for manganese and zinc.Q33761982
Clinical outcomes of hospital-acquired infection with Acinetobacter nosocomialis and Acinetobacter pittiiQ33798301
Occupational transmission of Acinetobacter baumannii from a United States serviceman wounded in Iraq to a health care workerQ33820538
Transferrin iron starvation therapy for lethal bacterial and fungal infectionsQ33883214
Acinetobacter baumannii response to host-mediated zinc limitation requires the transcriptional regulator ZurQ33899575
Risk factors and outcomes for patients with bloodstream infection due to Acinetobacter baumannii-calcoaceticus complexQ34058025
Epidemic diffusion of OXA-23-producing Acinetobacter baumannii isolates in Italy: results of the first cross-sectional countrywide surveyQ34058739
Community-acquired Acinetobacter meningitis in adultsQ34119206
Diversity within the O-linked protein glycosylation systems of acinetobacter speciesQ34157681
Analysis of the role of the LH92_11085 gene of a biofilm hyper-producing Acinetobacter baumannii strain on biofilm formation and attachment to eukaryotic cellsQ36913299
Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146aQ36920951
Mutations Decreasing Intrinsic β-Lactam Resistance Are Linked to Cell Division in the Nosocomial Pathogen Acinetobacter baumanniiQ36933374
Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania.Q36949518
H-NS plays a role in expression of Acinetobacter baumannii virulence features.Q36970729
IncM Plasmid R1215 Is the Source of Chromosomally Located Regions Containing Multiple Antibiotic Resistance Genes in the Globally Disseminated Acinetobacter baumannii GC1 and GC2 Clones.Q36986499
A mouse model of Acinetobacter baumannii-associated pneumonia using a clinically isolated hypervirulent strainQ37036579
Role of NADPH phagocyte oxidase in host defense against acute respiratory Acinetobacter baumannii infection in miceQ37099423
In Vivo Application of Bacteriophage as a Potential Therapeutic Agent To Control OXA-66-Like Carbapenemase-Producing Acinetobacter baumannii Strains Belonging to Sequence Type 357.Q37122285
Functional features of TonB energy transduction systems of Acinetobacter baumanniiQ37123826
Colistin resistance in a clinical Acinetobacter baumannii strain appearing after colistin treatment: effect on virulence and bacterial fitness.Q37124050
Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment optionsQ37150308
Rapid determination of quinolone resistance in Acinetobacter spp.Q37191622
Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis.Q37213637
GES-11, a novel integron-associated GES variant in Acinetobacter baumanniiQ37274713
Personalized Therapeutic Cocktail of Wild Environmental Phages Rescues Mice from Acinetobacter baumannii Wound Infections.Q37287693
Trends in antibiotic resistance among major bacterial pathogens isolated from blood cultures tested at a large private laboratory network in India, 2008-2014.Q37338009
Iron acquisition functions expressed by the human pathogen Acinetobacter baumanniiQ37364565
A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecyclineQ37374012
The contribution of nutrient metal acquisition and metabolism to Acinetobacter baumannii survival within the hostQ37385154
Health-care associated infections rates, length of stay, and bacterial resistance in an intensive care unit of Morocco: findings of the International Nosocomial Infection Control Consortium (INICC).Q37395537
Inhaled colistin for treatment of pneumonia due to colistin-only-susceptible Acinetobacter baumannii.Q37418760
Microbial profile of early and late onset ventilator associated pneumonia in the intensive care unit of a tertiary care hospital in bangalore, IndiaQ37429651
Biological cost of different mechanisms of colistin resistance and their impact on virulence in Acinetobacter baumannii.Q37544333
In vitro responses of Acinetobacter baumannii to two- and three-drug combinations following exposure to colistin and doripenem.Q37544741
Clinical experience of colistin-glycopeptide combination in critically ill patients infected with Gram-negative bacteriaQ37544860
Validation of a novel murine wound model of Acinetobacter baumannii infectionQ37643643
Hospital acquired infections among patients admitted in the medical and surgical wards of a non-teaching secondary care hospital in northern India.Q37679110
Morphine, but not trauma, sensitizes to systemic Acinetobacter baumannii infectionQ37680545
Insights into acinetobacter war-wound infections, biofilms, and controlQ37714265
Treatment of Acinetobacter infections.Q37760952
Confronting multidrug-resistant Acinetobacter baumannii: a reviewQ37815829
Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategiesQ37996299
Acinetobacter baumannii: human infections, factors contributing to pathogenesis and animal modelsQ38008459
Clinical outcomes with extended or continuous versus short-term intravenous infusion of carbapenems and piperacillin/tazobactam: a systematic review and meta-analysisQ38052888
Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages.Q38057841
Emerging therapies for multidrug resistant Acinetobacter baumanniiQ38073927
Systematic review and meta-analysis of in vitro synergy of polymyxins and carbapenemsQ38126768
Community-acquired necrotizing fasciitis caused by Acinetobacter calcoaceticus: a case report and literature reviewQ38186236
Combination antibiotic treatment versus monotherapy for multidrug-resistant, extensively drug-resistant, and pandrug-resistant Acinetobacter infections: a systematic reviewQ38212031
Carbapenem resistance in Pseudomonas aeruginosa and Acinetobacter baumannii in the nosocomial setting in Latin America.Q38243475
A review of intravenous minocycline for treatment of multidrug-resistant Acinetobacter infectionsQ38265153
A GC1 Acinetobacter baumannii isolate carrying AbaR3 and the aminoglycoside resistance transposon TnaphA6 in a conjugative plasmid.Q38294708
Molecular Epidemiology and Mechanisms of Carbapenem Resistance of Acinetobacter spp. in Asia and OceaniaQ38365121
Genetic tools for manipulating Acinetobacter baumannii genome: an overviewQ38463382
High prevalence of multidrug-resistant nonfermenters in hospital-acquired pneumonia in AsiaQ38470424
Serum resistance of Acinetobacter baumannii through the binding of factor H to outer membrane proteinsQ38491423
In vitro activity of colistin in antimicrobial combination against carbapenem-resistant Acinetobacter baumannii isolated from patients with ventilator-associated pneumonia in VietnamQ38495174
Combined therapy for multi-drug-resistant Acinetobacter baumannii infection--is there evidence outside the laboratory?Q38556441
Structure and context of Acinetobacter transposons carrying the oxa23 carbapenemase gene.Q38692948
Characterization of surface antigen protein 1 (SurA1) from Acinetobacter baumannii and its role in virulence and fitnessQ38782983
Amplification of aminoglycoside resistance gene aphA1 in Acinetobacter baumannii results in tobramycin therapy failureQ38873222
Community-acquired bacteremic Acinetobacter pneumonia in tropical Australia is caused by diverse strains of Acinetobacter baumannii, with carriage in the throat in at-risk groupsQ38876666
Intranasal treatment with bacteriophage rescues mice from Acinetobacter baumannii-mediated pneumoniaQ38902086
The Acinetobacter baumannii Omp33-36 porin is a virulence factor that induces apoptosis and modulates autophagy in human cellsQ38962879
KatG and KatE confer Acinetobacter resistance to hydrogen peroxide but sensitize bacteria to killing by phagocytic respiratory burst.Q39017163
Association of the outer membrane protein Omp33 with fitness and virulence of Acinetobacter baumanniiQ39116650
The sensor kinase BfmS mediates virulence in Acinetobacter baumannii.Q39186713
New Delhi metallo-β-lactamase-producing Acinetobacter baumannii: a novel paradigm for spreading antibiotic resistance genesQ39297102
Risk factors and mortality of patients with nosocomial carbapenem-resistant Acinetobacter baumannii pneumoniaQ39300668
The value of single-pathogen antibacterial agents.Q39309271
Diversity of Acinetobacter baumannii strains isolated in humans, companion animals, and the environment in Reunion Island: an exploratory study.Q39333801
Distribution and in vitro antimicrobial susceptibility of Acinetobacter species on the skin of healthy humansQ39342649
Randomized controlled trial of nebulized colistimethate sodium as adjunctive therapy of ventilator-associated pneumonia caused by Gram-negative bacteriaQ39385974
In vitro and in vivo reduced fitness and virulence in ciprofloxacin-resistant Acinetobacter baumannii.Q39442834
Surveillance for and susceptibility of Acinetobacter baumannii in a large hospital and burn center in Shanghai, China, 2007-2013.Q39470106
Clinical epidemiology, treatment and prognostic factors of extensively drug-resistant Acinetobacter baumannii ventilator-associated pneumonia in critically ill patients.Q39472836
Comparison of tigecycline with imipenem/cilastatin for the treatment of hospital-acquired pneumoniaQ42905606
"Airborne assault": a new dimension in Acinetobacter baumannii transmission*.Q42924406
Impaired virulence and fitness of a colistin-resistant clinical isolate of Acinetobacter baumannii in a rat model of pneumoniaQ42930254
Steady-state pharmacokinetics and BAL concentration of colistin in critically Ill patients after IV colistin methanesulfonate administrationQ43014198
Combination Therapy for Extreme Drug-Resistant Acinetobacter baumannii: Ready for Prime Time?Q43202091
Editorial commentary: Polymyxin-resistant Acinetobacter baumannii: urgent action neededQ43226964
Global spread of carbapenem-resistant Acinetobacter baumanniiQ43227337
Diabetic murine models for Acinetobacter baumannii infectionQ43237805
Epidemiology and impact of imipenem resistance in Acinetobacter baumanniiQ43254058
Summary trends for the Meropenem Yearly Susceptibility Test Information Collection Program: a 10-year experience in the United States (1999-2008).Q43260620
The structure of the polysaccharide isolated from Acinetobacter baumannii strain LAC-4.Q43463983
Epidemic multidrug-resistant Acinetobacter baumannii related to European clonal types I and II in Rome (Italy).Q43473623
A common pathway for O-linked protein-glycosylation and synthesis of capsule in Acinetobacter baumanniiQ43499545
Influence of iron on growth, production of siderophore compounds, membrane proteins, and lipase activity in Acinetobacter calcoaceticus BD 413.Q43571316
A multicenter case-case control study for risk factors and outcomes of extensively drug-resistant Acinetobacter baumannii bacteremiaQ43574348
Osteomyelitis in military personnel wounded in Iraq and AfghanistanQ43635993
Some immunological properties of lipopolysaccharide from Acinetobacter baumanniiQ43790242
Effect of aminoglycoside and beta-lactam combination therapy versus beta-lactam monotherapy on the emergence of antimicrobial resistance: a meta-analysis of randomized, controlled trialsQ44023944
Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort studyQ44043080
pACICU2 is a conjugative plasmid of Acinetobacter carrying the aminoglycoside resistance transposon TnaphA6.Q44095392
Relationship between beta-lactamase production, outer membrane protein and penicillin-binding protein profiles on the activity of carbapenems against clinical isolates of Acinetobacter baumanniiQ44342508
Dissemination of New Delhi metallo-β-lactamase-1-producing Acinetobacter baumannii in EuropeQ44551413
Infections in combat casualties during Operations Iraqi and Enduring FreedomQ44718619
Distribution of Acinetobacter species on skin of healthy humansQ44759996
International study of the prevalence and outcomes of infection in intensive care unitsQ44988294
Tn6168, a transposon carrying an ISAba1-activated ampC gene and conferring cephalosporin resistance in Acinetobacter baumanniiQ45051391
The siderophore-mediated iron acquisition systems of Acinetobacter baumannii ATCC 19606 and Vibrio anguillarum 775 are structurally and functionally relatedQ45140773
Emergence of carbapenem-resistant Acinetobacter in a temperate north Indian StateQ45399885
Comparison of 30-min and 3-h infusion regimens for imipenem/cilastatin and for meropenem evaluated by Monte Carlo simulationQ45580188
Colistin and rifampicin compared with colistin alone for the treatment of serious infections due to extensively drug-resistant Acinetobacter baumannii: a multicenter, randomized clinical trial.Q45974680
Serum resistance, gallium nitrate tolerance and extrapulmonary dissemination are linked to heme consumption in a bacteremic strain of Acinetobacter baumannii.Q45992218
Inhaled colistin as monotherapy for multidrug-resistant gram (-) nosocomial pneumonia: a case seriesQ46177552
Impact of carbapenem resistance and receipt of active antimicrobial therapy on clinical outcomes of Acinetobacter baumannii bloodstream infections.Q35270405
Molecular epidemiology of carbapenem-nonsusceptible Acinetobacter baumannii in the United States.Q35530666
Colistin-resistant Acinetobacter baumannii: beyond carbapenem resistanceQ35551122
Resources for Genetic and Genomic Analysis of Emerging Pathogen Acinetobacter baumanniiQ35595613
Host fate is rapidly determined by innate effector-microbial interactions during Acinetobacter baumannii bacteremiaQ35661920
Fitness cost of antibiotic susceptibility during bacterial infectionQ35707529
Transition of blaOXA-58-like to blaOXA-23-like in Acinetobacter baumannii Clinical Isolates in Southern China: An 8-Year StudyQ35764830
Acinetobacter baumannii Virulence Is Mediated by the Concerted Action of Three Phospholipases D.Q35778670
A retrospective study of the incidence, clinical characteristics, identification, and antimicrobial susceptibility of bacteremic isolates of Acinetobacter ursingii.Q35794129
Role of acinetobactin-mediated iron acquisition functions in the interaction of Acinetobacter baumannii strain ATCC 19606T with human lung epithelial cells, Galleria mellonella caterpillars, and miceQ35805487
Cryopreservation of virulent Acinetobacter baumannii to reduce variability of in vivo studiesQ35829780
Host-Microbe Protein Interactions during Bacterial InfectionQ35835388
Multidrug-resistant Acinetobacter extremity infections in soldiersQ35873386
Severe Community-Acquired Bloodstream Infection with Acinetobacter ursingii in Person who Injects DrugsQ35874041
Tigecycline treatment experience against multidrug-resistant Acinetobacter baumannii infections: a systematic review and meta-analysisQ35888304
Optimizing antimicrobial pharmacodynamics: dosage strategies for meropenemQ35914401
Genetic analysis of surface motility in Acinetobacter baumanniiQ35959825
Molecular characterization and antimicrobial susceptibility of Acinetobacter baumannii isolates obtained from two hospital outbreaks in Los Angeles County, California, USAQ36008636
Acinetobacter skin colonization of US Army SoldiersQ79811618
Antimicrobial resistance of Acinetobacter baumannii: six years of National Antimicrobial Resistance Surveillance Thailand (NARST) surveillanceQ83368782
Use of adjunctive aerosolized antimicrobial therapy in the treatment of Pseudomonas aeruginosa and Acinetobacter baumannii ventilator-associated pneumoniaQ83473464
Gram-negative osteomyelitis: clinical and microbiological profileQ83494833
Acinetobacter infections in a tertiary level intensive care unit in northern India: epidemiology, clinical profiles and outcomesQ84026157
High susceptibility to respiratory Acinetobacter baumannii infection in A/J mice is associated with a delay in early pulmonary recruitment of neutrophilsQ84159892
Inhaled colistin as adjunctive therapy to intravenous colistin for the treatment of microbiologically documented ventilator-associated pneumonia: a comparative cohort studyQ84516666
Aerosolized Colistin for the Treatment of Multidrug-resistant Acinetobacter baumannii Pneumonia: Experience in a Tertiary Care Hospital in Northern TaiwanQ84675360
Attenuated virulence of a slow-growing pandrug-resistant Acinetobacter baumannii is associated with decreased expression of genes encoding the porins CarO and OprD-likeQ84974548
Multidrug-resistant Acinetobacter baumannii causing necrotizing fasciitis in a pancreas-kidney transplant recipient: a case reportQ85007190
Eradication of multidrug-resistant Acinetobacter baumannii from the respiratory tract with inhaled colistin methanesulfonate: a matched case-control studyQ85096838
Minocycline: an old drug for a new bug: multidrug-resistant Acinetobacter baumanniiQ85911482
Clinical implications of glycoproteomics for Acinetobacter baumanniiQ86247890
Clinical outcomes of tigecycline alone or in combination with other antimicrobial agents for the treatment of patients with healthcare-associated multidrug-resistant Acinetobacter baumannii infectionsQ86533675
Aerosolization of Acinetobacter baumannii in a trauma ICU*Q86976740
Acinetobacter baumannii K27 and K44 capsular polysaccharides have the same K unit but different structures due to the presence of distinct wzy genes in otherwise closely related K gene clustersQ86985305
High prevalence of closely-related Acinetobacter baumannii in pets according to a multicentre study in veterinary clinics, Reunion IslandQ87419028
Acinetobacter baumannii isolates associated with community-acquired pneumonia in West ChinaQ87430368
A case-control study to identify predictors of 14-day mortality following carbapenem-resistant Acinetobacter baumannii bacteraemiaQ88082413
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpathophysiologyQ1135939
Acinetobacter infectious diseaseQ18975322
P304page(s)409-447
P577publication date2017-01-01
P1433published inClinical Microbiology ReviewsQ5133777
P1476titleClinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges
P478volume30

Reverse relations

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