UCP1: A transporter for H+ and fatty acid anions

scientific article published on 27 October 2016

UCP1: A transporter for H+ and fatty acid anions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BIOCHI.2016.10.013
P932PMC publication ID5461058
P698PubMed publication ID27984203

P2093author name stringAmbre M Bertholet
Yuriy Kirichok
P2860cites workStructure of mitochondrial ADP/ATP carrier in complex with carboxyatractylosideQ27642491
Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searchingQ27670979
Coupling of proton and substrate translocation in the transport cycle of mitochondrial carriersQ28286811
The mechanism of transport by mitochondrial carriers based on analysis of symmetryQ28300538
Mechanism of fatty-acid-dependent UCP1 uncoupling in brown fat mitochondriaQ28506657
Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1Q28512763
Brown adipose tissue: function and physiological significanceQ29547448
Physiological regulation of the transport activity in the uncoupling proteins UCP1 and UCP2.Q32139124
A history of the first uncoupling protein, UCP1.Q33827372
Brown-Adipose-Tissue Mitochondria. The Influence of Albumin and Nucleotides on Passive Ion PermeabilitiesQ34218564
A history of UCP1.Q34439561
Mitochondrial carriers in the cytoplasmic state have a common substrate binding siteQ34479532
Electrophysiological insights into the mechanism of ion-coupled cotransportersQ35689276
The physiological regulation of uncoupling proteinsQ36489380
Channel character of uncoupling protein-mediated transportQ36744225
The ADP and ATP transport in mitochondria and its carrierQ37176693
Wanderings in bioenergetics and biomembranesQ37696617
Mitochondrial transporters of the SLC25 family and associated diseases: a reviewQ38209474
The Effective Proton Conductance of the Inner Membrane of Mitochondria from Brown Adipose Tissue. Dependency on Proton Electrochemical Potential GradientQ39159304
Thermogenic mechanisms in brown fatQ40140016
The uncoupling protein from brown fat mitochondria is related to the mitochondrial ADP/ATP carrier. Analysis of sequence homologies and of folding of the protein in the membrane.Q41415964
The reconstituted isolated uncoupling protein is a membrane potential driven H+ translocatorQ41429357
Evolutionarily distinct residues in the uncoupling protein UCP1 are essential for its characteristic basal proton conductanceQ42685675
Role of intrahelical arginine residues in functional properties of uncoupling protein (UCP1).Q43585940
Binding of fatty acids to the uncoupling protein from brown adipose tissue mitochondriaQ44368339
Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids.Q44945464
The mechanism of proton transport mediated by mitochondrial uncoupling proteinsQ45345681
Effect of fatty acids on H+ transport activity of the reconstituted uncoupling protein.Q45345682
The uncoupling protein UCP1 does not increase the proton conductance of the inner mitochondrial membrane by functioning as a fatty acid anion transporterQ47982245
The mitochondrial uncoupling-protein homologuesQ50308475
Dangerous liaisons between detergents and membrane proteins. The case of mitochondrial uncoupling protein 2.Q51785935
Palmitoyl coenzyme A: a possible physiological regulator of nucleotide binding to brown adipose tissue mitochondriaQ67549355
Mitochondrial protein alteration in active brown fat: a soidum dodecyl sulfate-polyacrylamide gel electrophoretic studyQ68229250
Differential interaction of fatty acids and fatty acyl CoA esters with the purified/reconstituted brown adipose tissue mitochondrial uncoupling proteinQ70145984
Brown-adipose-tissue mitochondria: the regulation of the 32000-Mr uncoupling protein by fatty acids and purine nucleotidesQ70179898
Characteristics of the isolated purine nucleotide binding protein from brown fat mitochondriaQ70423031
Site-directed mutagenesis identifies residues in uncoupling protein (UCP1) involved in three different functionsQ73570942
Structure and function of the uncoupling protein from brown adipose tissueQ77796455
P921main subjectfatty acidQ61476
P304page(s)28-34
P577publication date2016-10-27
P1433published inBiochimieQ2904035
P1476titleUCP1: A transporter for H+ and fatty acid anions
P478volume134

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cites work (P2860)
Q908483243-Mercaptopyruvate sulfurtransferase disruption in dermal fibroblasts facilitates adipogenic trans-differentiation
Q100491018ATP modulates SLC7A5 (LAT1) synergistically with cholesterol
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Q47096943FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes
Q92154291H+ transport is an integral function of the mitochondrial ADP/ATP carrier
Q64264371Important Trends in UCP3 Investigation
Q92710037Mitochondrial 2,4-dienoyl-CoA reductase (Decr) deficiency and impairment of thermogenesis in mouse brown adipose tissue
Q46195724Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling
Q46316125Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms
Q92497883Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity
Q54966402Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies.

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