The DeISGylase USP18 limits TRAIL-induced apoptosis through the regulation of TRAIL levels: Cellular levels of TRAIL influences responsiveness to TRAIL-induced apoptosis.

scientific article published on 19 September 2013

The DeISGylase USP18 limits TRAIL-induced apoptosis through the regulation of TRAIL levels: Cellular levels of TRAIL influences responsiveness to TRAIL-induced apoptosis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4161/CBT.26525
P932PMC publication ID3912039
P698PubMed publication ID24153058
P5875ResearchGate publication ID258038711

P50authorClaudio BrancoliniQ56697346
P2093author name stringHarish Potu
Andrea Sgorbissa
Ivana Manini
Andrea Tomasella
P2860cites workBortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosisQ24300558
The receptor for the cytotoxic ligand TRAILQ24310481
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.Q24314730
Inhibition of death receptor signals by cellular FLIPQ24316446
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activityQ24337310
UBP43 (USP18) specifically removes ISG15 from conjugated proteinsQ27863712
An antagonist decoy receptor and a death domain-containing receptor for TRAILQ28245153
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAILQ28250747
Interferons at age 50: past, current and future impact on biomedicineQ28259312
Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosisQ28646425
Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis.Q33257957
Activation of the Akt survival pathway contributes to TRAIL resistance in cancer cellsQ33564264
PLANdbAffy: probe-level annotation database for Affymetrix expression microarraysQ33600942
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.Q34006269
Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathwayQ34786865
On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeuticsQ35853714
Regulation in the targeting of TRAIL receptor 1 to cell surface via GODZ for TRAIL sensitivity in tumor cellsQ36028494
Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cellsQ36339240
Playing the DISC: turning on TRAIL death receptor-mediated apoptosis in cancerQ37644600
Sensitization of (colon) cancer cells to death receptor related therapies: a report from the FP6-ONCODEATH research consortiumQ37992502
Regulation of the human TRAIL gene.Q38034651
IFNs, ISGylation and cancer: Cui prodest?Q38036017
Type I IFNs signaling and apoptosis resistance in glioblastoma cells.Q39486541
Death receptor 4 is preferentially recruited to lipid rafts in chronic lymphocytic leukemia cells contributing to tumor necrosis related apoptosis inducing ligand-induced synergistic apoptotic responsesQ39519488
Identification of USP18 as an important regulator of the susceptibility to IFN-alpha and drug-induced apoptosisQ39752787
Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of the ubiquitin-proteasome systemQ39779474
Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells.Q40105431
Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein responseQ40118478
The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cellsQ40131236
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cellsQ40559201
Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL.Q42523097
Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNsQ42944061
Histone deacetylase inhibitors sensitize human colonic adenocarcinoma cell lines to TNF-related apoptosis inducing ligand-mediated apoptosis.Q43961658
TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB.Q44482351
The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cellsQ44539646
Multiple mechanisms underlie resistance of leukemia cells to Apo2 Ligand/TRAIL.Q53591297
Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.Q55473556
Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cellsQ73405489
IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosisQ74410110
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)1158-1166
P577publication date2013-09-19
P1433published inCancer Biology and TherapyQ2544651
P1476titleThe DeISGylase USP18 limits TRAIL-induced apoptosis through the regulation of TRAIL levels: Cellular levels of TRAIL influences responsiveness to TRAIL-induced apoptosis
P478volume14

Reverse relations

cites work (P2860)
Q50045539CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages.
Q46359145Deubiquitinase Usp18 prevents cellular apoptosis from oxidative stress in liver cells
Q99591319Emerging Roles of USP18: From Biology to Pathophysiology
Q49990366Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target
Q41925201Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1.
Q38997388Multiple functions of USP18.
Q92219042The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity
Q59329027USP18 - a multifunctional component in the interferon response
Q35654199USP18 Sensitivity of Peptide Transporters PEPT1 and PEPT2.

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