scholarly article | Q13442814 |
P356 | DOI | 10.1038/NCB2793 |
P953 | full work available online at | http://www.nature.com/articles/ncb2793 |
http://www.nature.com/articles/ncb2793.pdf | ||
P698 | PubMed publication ID | 23811686 |
P5875 | ResearchGate publication ID | 243967928 |
P50 | author | Filippo Rosselli | Q89612495 |
P2093 | author name string | Valeria Naim | |
Michelle Debatisse | |||
Therese Wilhelm | |||
P2860 | cites work | Hallmarks of Cancer: The Next Generation | Q22252312 |
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair | Q24313572 | ||
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair | Q24314301 | ||
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases | Q24314357 | ||
Mus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cells | Q24607828 | ||
Molecular pathogenesis and clinical management of Fanconi anemia | Q24621696 | ||
Mutations of the SLX4 gene in Fanconi anemia | Q24628650 | ||
Human Mus81-associated endonuclease cleaves Holliday junctions in vitro | Q28210371 | ||
Chromosome fragile sites | Q28235126 | ||
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions | Q29614216 | ||
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis | Q29614217 | ||
Mus81-Eme1 are essential components of a Holliday junction resolvase | Q29619843 | ||
Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes | Q34025948 | ||
Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites | Q34212683 | ||
Dynamic molecular combing: stretching the whole human genome for high-resolution studies. | Q34437508 | ||
Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site | Q34626544 | ||
Replication stress induces 53BP1-containing OPT domains in G1 cells | Q34854577 | ||
The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities | Q34982804 | ||
The FANC pathway and mitosis: a replication legacy | Q35001182 | ||
Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I–DNA complexes | Q35670720 | ||
Structural and functional relationships of the XPF/MUS81 family of proteins | Q37179480 | ||
Common fragile sites: mechanisms of instability revisited. | Q37957550 | ||
Molecular profiling of common fragile sites in human fibroblasts. | Q39447595 | ||
The knock-down of ERCC1 but not of XPF causes multinucleation | Q39490781 | ||
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress | Q39593027 | ||
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. | Q39847635 | ||
Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis | Q42007696 | ||
Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4. | Q42030288 | ||
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges | Q42431691 | ||
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. | Q47074397 | ||
Mitotic catastrophe: a mechanism for avoiding genomic instability | Q52610466 | ||
Xeroderma pigmentosum group F protein binds to Eg5 and is required for proper mitosis: implications for XP-F and XFE. | Q53184209 | ||
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype | Q55671559 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1008-1015 | |
P577 | publication date | 2013-06-30 | |
P1433 | published in | Nature Cell Biology | Q1574111 |
P1476 | title | ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis | |
ERCC1 and MUS81–EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis | |||
P478 | volume | 15 |
Q97587342 | 3D genome organization contributes to genome instability at fragile sites |
Q50301065 | 53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process. |
Q47880362 | A blooming resolvase at chromosomal fragile sites. |
Q33635514 | A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression. |
Q58553479 | A journey with common fragile sites: from S-phase to telophase |
Q52746256 | A meeting at risk: Unrepaired DSBs go for broke |
Q58028376 | A new class of ultrafine anaphase bridges generated by homologous recombination |
Q92024320 | ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress |
Q30654027 | ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission |
Q39012252 | ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency |
Q99616903 | Acquired genetic changes in human pluripotent stem cells: origins and consequences |
Q36545834 | Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. |
Q39035029 | Alternative roles for oxidized mCs and TETs |
Q94466519 | An advanced cell cycle tag toolbox reveals principles underlying temporal control of structure-selective nucleases |
Q96576723 | Antitumor effect of a WEE1 inhibitor and potentiation of olaparib sensitivity by DNA damage response modulation in triple-negative breast cancer |
Q47186808 | Around and beyond 53BP1 Nuclear Bodies |
Q38711574 | Arsenic-induced sumoylation of Mus81 is involved in regulating genomic stability |
Q37170604 | BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells |
Q41125254 | BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination. |
Q26858910 | Breaking bad: R-loops and genome integrity |
Q34394094 | Causes and consequences of replication stress |
Q39010240 | Centromere Stability: The Replication Connection |
Q41816072 | Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements. |
Q38365781 | Chromosome Dynamics during Mitosis |
Q60935156 | Common Chromosomal Fragile Sites-Conserved Failure Stories |
Q99614287 | Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress |
Q90284729 | Common fragile sites: protection and repair |
Q39391040 | Control of Mus81 nuclease during the cell cycle |
Q39192675 | Control of structure-specific endonucleases to maintain genome stability |
Q50660324 | Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression |
Q24294687 | Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substrates |
Q90461207 | Current Understanding of RAD52 Functions: Fundamental and Therapeutic Insights |
Q38736198 | DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks. |
Q30842780 | DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression. |
Q38209320 | DNA damage repair machinery and HIV escape from innate immune sensing. |
Q38652528 | DNA replication stress and cancer: cause or cure? |
Q90611794 | DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF |
Q26862285 | DNA replication stress: causes, resolution and disease |
Q30300009 | DNA secondary structure at chromosomal fragile sites in human disease |
Q55286515 | Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair. |
Q64889763 | Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse. |
Q34987379 | ERCC1 function in nuclear excision and interstrand crosslink repair pathways is mediated exclusively by the ERCC1-202 isoform |
Q64386732 | ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures |
Q37577441 | Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains |
Q39261664 | FANCD2 Facilitates Replication through Common Fragile Sites. |
Q34115459 | Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair |
Q39455549 | Fragile sites in cancer: more than meets the eye. |
Q89880050 | From R-Loops to G-Quadruplexes: Emerging New Threats for the Replication Fork |
Q60916341 | Function and Interactions of ERCC1-XPF in DNA Damage Response |
Q64388787 | Genome-wide mapping of 8-oxo-7,8-dihydro-2'-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells |
Q38382440 | Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes |
Q39154178 | Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells. |
Q52568681 | Homologous Recombination and Replication Fork Protection: BRCA2 and More! |
Q93375413 | Homologous Recombination and the Formation of Complex Genomic Rearrangements |
Q37241758 | How unfinished business from S-phase affects mitosis and beyond |
Q38659673 | Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer |
Q38258279 | Interplay between genetic and epigenetic factors governs common fragile site instability in cancer |
Q35042952 | Large transcription units unify copy number variants and common fragile sites arising under replication stress |
Q41077646 | MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells |
Q38996639 | MUS81-EME2 promotes replication fork restart |
Q26738970 | Maintaining Genome Stability in Defiance of Mitotic DNA Damage |
Q94559563 | Mechanisms Underlying Recurrent Genomic Amplification in Human Cancers |
Q92509341 | Mild replication stress causes chromosome mis-segregation via premature centriole disengagement |
Q92229730 | Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements |
Q39363647 | Mitotic Dysfunction Associated with Aging Hallmarks |
Q92612315 | Mitotic functions of poly(ADP-ribose) polymerases |
Q49646612 | Multifaceted Fanconi Anemia Signaling. |
Q40971773 | Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability |
Q34898909 | Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance |
Q26822478 | Nucleases in homologous recombination as targets for cancer therapy |
Q47110403 | Oncogene-Induced Replication Stress Drives Genome Instability and Tumorigenesis. |
Q39014876 | Order from clutter: selective interactions at mammalian replication origins |
Q52716634 | Pathways for maintenance of telomeres and common fragile sites during DNA replication stress |
Q54977571 | Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress |
Q34262604 | Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1. |
Q24318920 | Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing |
Q90142332 | Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells |
Q58701167 | Preserving replication fork integrity and competence via the homologous recombination pathway |
Q41077638 | Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells |
Q35693354 | Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA. |
Q92203104 | RAD51 and mitotic function of mus81 are essential for recovery from low-dose of camptothecin in the absence of the WRN exonuclease |
Q37396238 | Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. |
Q52884815 | Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation |
Q60955060 | Regulation of Structure-Specific Endonucleases in Replication Stress |
Q99614266 | Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome |
Q90383064 | Replication Stress Response Links RAD52 to Protecting Common Fragile Sites |
Q38248717 | Replication fork recovery and regulation of common fragile sites stability |
Q38365123 | Replication fork reversal in eukaryotes: from dead end to dynamic response |
Q37389940 | Replication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1. |
Q38814576 | Replication stress activates DNA repair synthesis in mitosis. |
Q34473453 | Replication stress and cancer |
Q28087011 | Replication stress in Mammalian cells and its consequences for mitosis |
Q27305589 | Replication stress in early S phase generates apparent micronuclei and chromosome rearrangement in fission yeast |
Q47552596 | Replication stress induces accumulation of FANCD2 at central region of large fragile genes. |
Q34550677 | Rescue from replication stress during mitosis |
Q38586814 | Resolution of Recombination Intermediates: Mechanisms and Regulation |
Q38134624 | Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes. |
Q38994662 | Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe |
Q64096515 | Sequence and Nuclease Requirements for Breakage and Healing of a Structure-Forming (AT)n Sequence within Fragile Site FRA16D |
Q26798438 | Sister chromatid decatenation: bridging the gaps in our knowledge |
Q27940191 | Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates |
Q64075900 | Structure-Specific Endonucleases and the Resolution of Chromosome Underreplication |
Q35034362 | Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function |
Q36441625 | Survivin contributes to DNA repair by homologous recombination in breast cancer cells |
Q60959771 | TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress |
Q35218132 | TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution |
Q38723121 | The "enemies within": regions of the genome that are inherently difficult to replicate |
Q54198689 | The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress. |
Q35456778 | The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage |
Q50086359 | The Detection and Analysis of Chromosome Fragile Sites. |
Q27312678 | The Fanconi Anemia C Protein Binds to and Regulates Stathmin-1 Phosphorylation |
Q24294529 | The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability |
Q42317231 | The SMX DNA Repair Tri-nuclease |
Q48274589 | The Structure-Specific Endonucleases MUS81 and SEND1 Are Essential for Telomere Stability in Arabidopsis. |
Q60958514 | The Unresolved Problem of DNA Bridging |
Q39051119 | The control of DNA repair by the cell cycle |
Q39438600 | The impact of replication stress on replication dynamics and DNA damage in vertebrate cells. |
Q90402483 | The role of fork stalling and DNA structures in causing chromosome fragility |
Q42576411 | TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells |
Q38809301 | TopBP1-mediated DNA processing during mitosis |
Q27934018 | TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability |
Q90833348 | Transcription-dependent regulation of replication dynamics modulates genome stability |
Q38994629 | Transcription-replication conflicts at chromosomal fragile sites-consequences in M phase and beyond |
Q28070247 | Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response |
Q37304981 | Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells |
Q48097725 | Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations |
Q38253494 | Updating the mechanisms of common fragile site instability: how to reconcile the different views? |
Q89862470 | Working on Genomic Stability: From the S-Phase to Mitosis |
Q28238027 | XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4 |
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