Antidepressants and the Muscarinic Acetylcholine Receptor

scientific article published on February 1, 1977

Antidepressants and the Muscarinic Acetylcholine Receptor is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1001/ARCHPSYC.1977.01770140126014
P953full work available at URLhttp://jamanetwork.com/journals/jamapsychiatry/fullarticle/491674
P698PubMed publication ID14603

P2093author name stringS. H. Snyder
H. I. Yamamura
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)236-239
P577publication date1977-02-01
P1433published inJAMA PsychiatryQ635830
Archives of General PsychiatryQ105737481
P1476titleAntidepressants and the Muscarinic Acetylcholine Receptor
P478volume34

Reverse relations

cites work (P2860)
Q710504793H-Imipramine binding sites in the rat brain. Selective localization on serotoninergic neurones
Q41551368A Pilot Study of the Mechanism of Action of Desipramine
Q34511940A double-blind placebo-controlled study to compare the autonomic effects of fluvoxamine with those of amitriptyline and doxepin in healthy volunteers
Q67777705A nicotinic receptor antagonist enhances the hypothermic response to a muscarinic agonist
Q68205188Acetylcholine and affective disorder
Q40504522Active hydroxymetabolites of antidepressants. Emphasis on E-10-hydroxy-nortriptyline
Q72506801Acute extrapyramidal side effects: Serum levels of neuroleptics and anticholinergics
Q41131303Adrenergic influences on the control of blood-brain barrier permeability.
Q40305443Adverse effects of antidepressant drugs. Part 2: 'Second generation' antidepressants and rational decision making in antidepressant therapy
Q35364211Adverse effects of antidepressants in the elderly
Q53864705Affinity of nortriptyline and its E-10-hydroxy metabolite for muscarinic receptors.
Q24615575Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity
Q72426458Amitriptyline: Long-term treatment elevates α-adrenergic and muscarinic receptor binding in mouse brain
Q52213214Amoxapine and amitriptyline. II. Specificity of cognitive effects during brief treatment of depression.
Q70770682An enhanced sensitivity of muscarinic cholinergic receptor associated with dopaminergic receptor subsensitivity after chronic antidepressant treatment
Q24672336Antagonism by antidepressants of muscarinic acetylcholine receptors of human brain
Q45227694Anticholinergic serum levels and cognitive performance
Q60050316Antidepressant drugs and ethanol: Behavioral and pharmacokinetic interactions in mice
Q70572446Antidepressant selection in the elderly
Q48945939Antidepressant withdrawal syndromes: phenomenology and pathophysiology
Q41041144Antidepressants and heart-rate variability in older adults: a population-based study
Q48728797Antidepressants and opiates interactions: pharmacological and biochemical evidences
Q35674766Antidepressants in the general hospital
Q40622075Antiparkinsonian drugs in the treatment of neuroleptic-induced extrapyramidal symptoms
Q34560423Antipsychotic withdrawal symptoms: phenomenology and pathophysiology
Q39577906Assessment and treatment of affective illness in the elderly
Q41839266Binding affinities of four tricyclic antidepressive drugs to muscarinic cholinergic receptors in human parotid gland
Q43203936Bradykinin receptors in intestinal smooth muscles and their post-receptor events related to calcium
Q44587875Brain histamine receptors as targets for antidepressant drugs
Q53201469Can an adjuvant treatment or a pharmacologic prevention be common to several diseases? The case of those associated to neuromediator defects
Q43610821Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization
Q40113701Central nervous system receptors in neuropsychiatric disorders
Q49111955Cerebral Histamine: Indications for Neuronal and Vascular Regulation
Q34409219Challenges and prospects for pharmacotherapy in functional gastrointestinal disorders.
Q70804779Characteristics and regulation of high affinity [3H]imipramine binding to rat hippocampal membranes
Q38967981Cholinergic involvement in mental disorders
Q33921518Cholinergic neurotransmission seems not to be involved in depression but possibly in personality
Q40137447Chronic antidepressant therapy and associated changes in central monoaminergic receptor functioning
Q48640640Chronic imipramine treatment-induced changes in acetylcholinesterase (EC 3.1.1.7) activity in discrete rat brain regions
Q72531337Clinical Psychiatry and Cardiovascular Disease in the Aged
Q71758586Clinical investigations into antidepressive mechanisms. I. Antihistaminic and cholinolytic effects: amitriptyline versus promethazine
Q69970878Clinical studies of the effect of (+) and (-)-oxaprotiline upon noradrenaline uptake
Q48661945Comparison of central gastric antisecretory effects of desmethylimipramine, doxepin and pirenzepine in rats
Q34622332Comparison of the effects of binodaline and amitriptyline on peripheral autonomic functions in healthy volunteers
Q34622686Comparison of the effects of chronic administration of ciclazindol and desipramine on pupillary responses to tyramine, methoxamine and pilocarpine in healthy volunteers
Q41987112Comparison of the effects of desipramine on noradrenaline- and methoxamine-evoked venoconstriction in man.
Q41781797Correlations between Serum Ami- and Nortriptyline Concentrations and Psychomotor Performance
Q40085183Current concepts on the mechanisms of action of antidepressant drugs
Q72427071Demonstration of specific “high affinity” binding sites for [3H] imipramine on human platelets
Q49157270Differential binding of 3H-imipramine and 3H-mianserin in rat cerebral cortex
Q52066687Distinct memory impairments following electroconvulsive therapy and imipramine.
Q70878250Distribution of Specific High‐Affinity Binding Sites for [3H]Imipramine in Human Brain
Q70883101Does high affinity [3H] imipramine binding label serotonin reuptake sites in brain and platelet?
Q38353242Drug safety and tolerability in prophylactic migraine treatment.
Q33718836Drug-induced cognitive impairment in the elderly
Q34009583Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management
Q69330525Dysbalance of neuronal second messenger function in the aetiology of affective disorders: a pathophysiological concept hypothesising defects beyond first messenger receptors
Q28194862Effect of amitriptyline on gastric ulceration
Q71050718Effect of antidepressant drugs on carbachol chloride-induced wet dog shake behaviour in rats
Q71248388Effect of antidepressant drugs on serotonergic and adrenergic receptors
Q51170618Effect of imipramine treatment on changes in heart rate and blood pressure during postural and isometric handgrip tests.
Q48153293Effect of nomifensine and other antidepressant drugs on acetylcholine turnover in various regions of rat brain
Q48512449Effect of tianeptine on the central cholinergic system: involvement of serotonin
Q34175745Effects of Antiparkinsonian Drugs on Muscarinic Receptor Binding in Rat Brain, Heart and Lung
Q72388743Effects of Desipramine Treatment upon Central Adrenoceptor Function in Normal Subjects
Q67272904Effects of acute and chronic desmethylimipramine on levels of cyclic AMP in vivo
Q37498394Effects of amitriptyline on gastric sensorimotor function and postprandial symptoms in healthy individuals: a randomized, double-blind, placebo-controlled trial
Q72890725Effects of antidepressant drugs on different receptors in the brain
Q51273301Effects of antidepressants and anticholinergics in a mouse “behavioral despair” test
Q44846262Effects of clonidine and tricyclic antidepressants on gastric smooth muscle contractility
Q43140189Effects of methylprednisolone on exercise-induced increases of plasma levels of polymorphonuclear elastase and myeloperoxidase in man. Preliminary results
Q72531398Effects of some rigid analogues of imipramine and amitriptyline on the uptake of noradrenaline, serotonin and choline in rat brain synaptosomes
Q70981219Effects of tricyclic antidepressants on muscarinic cholinergic receptor binding in mouse brain
Q39926908Evidence for the pharmacological similarity between the central presynaptic muscarinic autoreceptor and postsynaptic muscarinic receptors
Q37423106Fluvoxamine: an antidepressant for the elderly?
Q49109788From animal experiments to clinical trials: Aspects of the transposition in psychopharmacology
Q34562556High affinity binding of 3H-paroxetine and 3H-imipramine to rat neuronal membranes
Q72431754High affinity binding of tricyclic antidepressants to histamine H1-receptors: Fact and artifact
Q41491757High-affinity 3H-imipramine binding in rat cerebral cortex
Q66921698Identification of direct competition for, and indirect influences on, striatal muscarinic cholinergic receptors: in vivo [3H]Quinuclidinyl benzilate binding in rats
Q48784337In vitro studies on the effect of beta-carbolines on the activities of acetylcholinesterase and choline acetyltransferase and on the muscarinic receptor binding of the rat brain.
Q51867649Individual differences in effects of tricyclic antidepressants and anticholinergic drugs on operant behavior in the squirrel monkey
Q35939213Influence of Amineptine on Changes of Blood Pressure Evoked by Norepinephrine and Dopamine
Q40715085Inhibition of SK3 channels in the TE671 human medulloblastoma cell line by desipramine and imipramine
Q43991996Inhibition of acetylcholinesterase from Electrophorus electricus (L.) by tricyclic antidepressants.
Q72905196Interaction of impramine with the ionic channel of the acetylcholine receptor of motor endplate and electric organ
Q48233456Interaction of psychotropic drugs with brain muscarinic cholinoceptors: similarities of biperiden with pirenzepine in receptor binding properties
Q53781942Interactions of tricyclic antidepressants with a synaptic ion channel
Q71051345Intraocular pressure in patients receiving psychotropic medications
Q44782601Lack of effect of ephedrine on opiate analgesia
Q40897368Learning and memory in monozygotic twins discordant for schizophrenia.
Q41445384Localization of [3H]-imipramine binding sites in rat brain by light microscopic autoradiography
Q72863771Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding
Q42857894Long-term atropine treatment lowers the efficacy of carbachol to stimulate phosphatidylinositol breakdown in the cerebral cortex and hippocampus of rats
Q73547431Long-term clomipramine treatment upregulates forebrain acetylcholine muscarinic receptors, and reduces behavioural sensitivity to scopolamine in mice
Q43698600Long-term treatment with antidepressant drugs reduces the sensitivity of cortical cholinergic neurons to the activating actions of stress and the anxiogenic drug FG 7142.
Q44489489Mapping muscarinic receptors in human and baboon brain using [N-11C-methyl]-benztropine.
Q33949205Medication safety in residential aged-care facilities: a perspective
Q48619904Memory effects of clomipramine treatment: Relationship to CSF monoamine metabolites and drug concentrations in plasma
Q33630488Metabolism of tricyclic antidepressants
Q48967980Modulation of rat brainα2- and β-adrenergic receptor sensitivity following long-term treatment with antidepressants
Q37808126Mood Drugs
Q70883147Muscarinic cholinergic binding sites on intact human lymphocytes
Q35228641Neural symptoms induced by tricyclic antidepressants: phenomenology and pathophysiology
Q38369124Neurobiology of brain-gut interactions. Implications for ulcer disease
Q48388239Neuropharmacological modification of central catecholamines: effects on pinealectomy-induced convulsions
Q40111587Neurotransmitter Hypotheses of Depression: Research Update
Q70460000Nitroimipramines - synthesis and pharmacological effects of potent long-acting inhibitors of [3H] serotonin uptake and [3H] imipramine binding
Q48249072Noradrenergic denervation prevents sensitization of rat forebrain neurons to serotonin by tricyclic antidepressant treatment
Q44656415PET quantification of muscarinic cholinergic receptors with [N-11C-methyl]-benztropine and application to studies of propofol-induced unconsciousness in healthy human volunteers
Q68697220Paraganglionic cell response to chronic imipramine and handling stress: an ultrastructural study
Q41333430Pargyline reduces/prevents neuroleptic-induced acute dystonia in monkeys
Q41337684Personality factors predisposing to depression correlate significantly negatively with M1-muscarinic and beta-adrenergic receptor densities on blood cells
Q40078001Pharmacologic Mechanisms of Action of Antidepressants
Q40087979Pharmacosexology: the effects of drugs on sexual function a review
Q44683069Potentiation of imipramine-induced antinociception by nicotine in the formalin test
Q42111038Principles of antidepressant use.
Q39470233Psychiatric drugs and inhibited female orgasm
Q36272836Psychoactive drugs and human sexual behavior: the role of serotonergic activity
Q34109378Psychopharmacology in medical practice--the benefits and the risks
Q72523432Rational Use of Psychoactive Drugs in the Geriatric Patient
Q34245764Receptor Binding Profile of Quinupramine, a New Tricyclic Antidepressant
Q47591134Relationship between extrapyramidal symptoms and serum anticholinergic levels in treated chronic schizophrenics
Q48165398Repeated electroconvulsive shock does not change [3H]-paroxetine binding to the 5-HT uptake site in rat cortical membranes
Q72465801Sedative/anxiolytic effects of antidepressants in animals
Q60050303Serotonergic potentiation of muscarinic agonist evoked tremor and salivation in rat and mouse
Q42267364Sexual dysfunction and clomipramine
Q42177042Sildenafil, a phosphodiesterase type 5 inhibitor, enhances the antidepressant activity of amitriptyline but not desipramine, in the forced swim test in mice
Q42156660Specific [3H]-imipramine binding in rat brain [proceedings]
Q41752061Specific tricyclic antidepressant binding sites in rat brain
Q39240480The "neuroleptic" antipsychotic drugs. 2. Neurologic side effects
Q38926516The Role of Metabolites of Antidepressants in the Treatment of Depression
Q24672644The binding of some antidepressant drugs to brain muscarinic acetylcholine receptors
Q42631406The cellular mechanism of action of nimodipine (BAY e 9736), a new calcium antagonist [proceedings]
Q70237305The cholinolytic biperiden in depression. An acute placebo controlled study
Q70477135The effect of aging on the positive chronotropic response to amitriptyline
Q72857040The effect of psychoactive drugs on beta-adrenergic receptor binding sites in rat brain
Q41897251The effects of BTS 54,505, a metabolite of sibutramine, on monoamine and excitatory amino acid-evoked responses in the rat dorsolateral geniculate nucleus in vivo
Q42225750The effects of alaproclate on the pupillary responses to tyramine, phenylephrine and pilocarpine in depressed patients
Q36097030The interaction of trazodone with rat brain muscarinic cholinoceptors
Q40844880The problems of anticholinergic adverse effects in older patients
Q44452773The short-term clinical efficacy of amitriptyline in the management of idiopathic feline lower urinary tract disease: a controlled clinical study
Q39371998The use of medicines with anticholinergic effects in older people: a population study in an urban area of Sweden
Q51261356Therapeutic usefulness of amitriptyline in spastic colon syndrome.
Q39725957Treatment-resistant depression in the elderly
Q34122901Tricyclic antidepressant drugs block histamine H2 receptor in brain
Q71572165Tricyclic antidepressants and peripheral anticholinergic activity
Q73981247Tricyclic antidepressants block cholinergic nicotinic receptors and ATP secretion in bovine chromaffin cells
Q39197698Tricyclic antidepressants block histamine H1 receptors of mouse neuroblastoma cells
Q39287214Tricyclic antidepressants: Potent blockade of histamine H1 receptors of guinea pig ileum
Q68546921Use of tricyclic antidepressants in patients with glaucoma. Assessment and appropriate precautions

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