scholarly article | Q13442814 |
P356 | DOI | 10.1111/NAN.12066 |
P698 | PubMed publication ID | 23741998 |
P50 | author | Francisco Wandosell | Q42702607 |
Juan José Garrido | Q50797821 | ||
Diana Simón | Q63884363 | ||
Maria Jose Benitez Moreno | Q67826008 | ||
Ana I Rojo | Q76310820 | ||
Juan Maria Torres | Q41271935 | ||
P2093 | author name string | A Cuadrado | |
M E Herva | |||
P2860 | cites work | Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium | Q43786473 |
Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol | Q44184136 | ||
Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol | Q44184139 | ||
PrP(106-126) activates neuronal intracellular kinases and Egr1 synthesis through activation of NADPH-oxidase independently of PrPc | Q46603299 | ||
Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: implications for Alzheimer's disease and prion-related encephalopathies. | Q46927043 | ||
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway | Q47762057 | ||
No propagation of prions in mice devoid of PrP. | Q48101222 | ||
Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion | Q48171711 | ||
Neurotoxicity of a prion protein fragment | Q48304223 | ||
Regulation of a site-specific phosphorylation of the microtubule-associated protein 2 during the development of cultured neurons | Q48382318 | ||
De novo induction of amyloid-β deposition in vivo | Q48863950 | ||
Activation of the JNK-c-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection. | Q48873095 | ||
Microtubule-associated protein-2 located in growth regions of rat hippocampal neurons is highly phosphorylated at its proline-rich region | Q49160361 | ||
Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. | Q51794745 | ||
Apoptosis-mediated neurotoxicity induced by beta-amyloid and PrP fragments. | Q53214282 | ||
Caspases find a new place to hide. | Q53338897 | ||
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms | Q24300933 | ||
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase | Q24336639 | ||
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection | Q24534939 | ||
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418 | Q27641873 | ||
Molecular mechanisms of neurotoxicity of pathological prion protein | Q28280873 | ||
APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity | Q28570827 | ||
Caspases: enemies within | Q29547315 | ||
Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 | ||
The renaissance of GSK3 | Q29616725 | ||
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription | Q31462537 | ||
Akt1/PKBalpha protects PC12 cells against the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium and reduces the levels of oxygen-free radicals | Q31847089 | ||
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway | Q34278037 | ||
Synaptic pathology and cell death in the cerebellum in Creutzfeldt-Jakob disease | Q35184541 | ||
Potential roles of insulin and IGF-1 in Alzheimer's disease. | Q35192493 | ||
Insulin signaling in the central nervous system: learning to survive | Q36568898 | ||
Cellular prion protein signaling in serotonergic neuronal cells | Q36779221 | ||
The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid | Q37112633 | ||
Endocytosis of prion protein is required for ERK1/2 signaling induced by stress-inducible protein 1. | Q37335792 | ||
Neuroprotective and neurotoxic signaling by the prion protein | Q37877631 | ||
Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. | Q39962425 | ||
Resistance of cell lines to prion toxicity aided by phospho-ERK expression | Q40034009 | ||
Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells | Q40251968 | ||
Molecular morphology and toxicity of cytoplasmic prion protein aggregates in neuronal and non-neuronal cells | Q40280647 | ||
Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation | Q40429251 | ||
The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity. | Q40445820 | ||
Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation. | Q40576035 | ||
Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells | Q40782705 | ||
Neuronal cell death in scrapie-infected mice is due to apoptosis | Q40979839 | ||
Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3 | Q41889838 | ||
Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment | Q41987801 | ||
Prion pathogenesis is independent of caspase-12. | Q42068269 | ||
P433 | issue | 3 | |
P921 | main subject | prion protein family | Q24724413 |
P304 | page(s) | 311-326 | |
P577 | publication date | 2014-04-01 | |
P1433 | published in | Neuropathology and Applied Neurobiology | Q7002494 |
P1476 | title | Dysfunction of the PI3K-Akt-GSK-3 pathway is a common feature in cell culture and in vivo models of prion disease | |
P478 | volume | 40 |