Immune modulation by dendritic-cell-based cancer vaccines

scientific article published on March 2017

Immune modulation by dendritic-cell-based cancer vaccines is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S12038-017-9665-X
P698PubMed publication ID28229976

P2093author name stringAshok Kumar Vaid
Minish Jain
Bandana Sharan
Chaitanya Kumar
Poonamalle Parthasarathy Bapsy
Sakshi Kohli
Venkata Sathya Suresh Attili
P2860cites workA phase 2, single-arm study of an autologous dendritic cell treatment against mucin 1 in patients with advanced epithelial ovarian cancerQ22001066
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICAQ22010440
Antigen presentation and T cell stimulation by dendritic cellsQ22255632
Natural selection of tumor variants in the generation of "tumor escape" phenotypesQ24551158
Safety, activity, and immune correlates of anti-PD-1 antibody in cancerQ24633070
mTOR regulates memory CD8 T-cell differentiationQ24648624
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytesQ24676216
Effects of imatinib on monocyte-derived dendritic cells are mediated by inhibition of nuclear factor-kappaB and Akt signaling pathwaysQ46365793
Poly(I:C) used for human dendritic cell maturation preserves their ability to secondarily secrete bioactive IL-12.Q47735411
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilegeQ47860342
Induction of antigen-specific immunity with a vaccine targeting NY-ESO-1 to the dendritic cell receptor DEC-205.Q50457532
The first 1000 dendritic cell vaccinees.Q50736412
Adoptive T-cell therapy is a promising salvage approach for advanced or recurrent metastatic cervical cancer.Q51035691
Natural Killer Cells Activated by MHC Class ILow Targets Prime Dendritic Cells to Induce Protective CD8 T Cell ResponsesQ52005024
Distinct patterns and kinetics of chemokine production regulate dendritic cell function.Q54093362
Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activationQ59055770
Dendritic cell-B-cell interaction: dendritic cells provide B cells with CD40-independent proliferation signals and CD40-dependent survival signalsQ61027295
Early events in dendritic cell maturation induced by LPSQ73205992
In vivo generation of human dendritic cell subsets by Flt3 ligandQ74055026
Expansion of Immunostimulatory Dendritic Cells from Peripheral Blood of Patients with CancerQ77941438
Generation of functionally mature dendritic cells from elutriated monocytes using polyinosinic : polycytidylic acid and soluble CD40 ligand for clinical applicationQ81947651
Open-label, multi-center, non-randomized, single-arm study to evaluate the safety and efficacy of dendritic cell immunotherapy in patients with refractory solid malignancies, on supportive careQ87120295
Randomized phase II--study evaluating EGFR targeting therapy with cetuximab in combination with radiotherapy and chemotherapy for patients with locally advanced pancreatic cancer--PARC: study protocol [ISRCTN56652283].Q24816432
Engineering opportunities in cancer immunotherapyQ26776373
Adoptive T-cell therapy for cancer: The era of engineered T cellsQ26800611
The blockade of immune checkpoints in cancer immunotherapyQ27860852
Dendritic cells and the control of immunityQ27860918
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
Regulation of cutaneous malignancy by gammadelta T cellsQ28188439
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenaseQ28204166
A human memory T cell subset with stem cell-like propertiesQ28248395
The future of immune checkpoint therapyQ28259862
EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturationQ28282903
The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab networkQ28485085
Cancer immunotherapy via dendritic cellsQ29615444
The immunobiology of cancer immunosurveillance and immunoeditingQ29616246
Taking dendritic cells into medicineQ29619243
Molecular identification of a danger signal that alerts the immune system to dying cellsQ29619497
Cancer immunotherapy comes of ageQ29619918
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivoQ30080006
Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor controlQ30311891
Molecular insights on the peripheral and intratumoral effects of systemic high-dose rIL-2 (aldesleukin) administration for the treatment of metastatic melanomaQ30423599
DCVax®-L--developed by Northwest BiotherapeuticsQ30875456
Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccinesQ33683185
Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance.Q33799806
Dendritic cells: immunological sentinels with a central role in health and disease.Q33890355
The feasibility and clinical effects of dendritic cell-based immunotherapy targeting synthesized peptides for recurrent ovarian cancerQ33939202
Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cellsQ34029001
Effects of cytokines on the culture and differentiation of dendritic cells in vitroQ34199832
Interesting possibilities to improve the safety and efficacy of ipilimumab (Yervoy).Q34232474
Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancerQ34362516
Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancerQ34543188
Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulationQ34611780
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.Q34657638
Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcelluloQ34666875
Nature's TRAIL--on a path to cancer immunotherapyQ35046572
The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapiesQ35207756
Interferon gamma stimulates cellular maturation of dendritic cell line DC2.4 leading to induction of efficient cytotoxic T cell responses and antitumor immunityQ40136235
A phase I clinical trial of CD1c (BDCA-1)+ dendritic cells pulsed with HLA-A*0201 peptides for immunotherapy of metastatic hormone refractory prostate cancerQ40170491
Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activityQ40372686
Efficient migration of dendritic cells toward lymph node chemokines and induction of T(H)1 responses require maturation stimulus and apoptotic cell interaction.Q40420976
Primary antitumor immune response mediated by CD4+ T cellsQ40444553
Phase I/II trial of melanoma patient-specific vaccine of proliferating autologous tumor cells, dendritic cells, and GM-CSF: planned interim analysis.Q40470967
Autologous dendritic cell vaccines for non-small-cell lung cancer.Q40535885
Immunotherapy of bladder cancer using autologous dendritic cells pulsed with human lymphocyte antigen-A24-specific MAGE-3 peptideQ40724059
Cytotoxic T-lymphocyte clones, established by stimulation with the HLA-A2 binding p5365-73 wild type peptide loaded on dendritic cells In vitro, specifically recognize and lyse HLA-A2 tumour cells overexpressing the p53 proteinQ40903376
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
Dendritic cells generated either from CD34+ progenitor cells or from monocytes differ in their ability to activate antigen-specific CD8+ T cells.Q40928292
Human Tumor Antigens and Cancer ImmunotherapyQ41533232
T cell responses: naive to memory and everything in betweenQ42727084
Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sitesQ42971765
Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicityQ43293818
Phenotypic and functional differences between human dendritic cells derived in vitro from hematopoietic progenitors and from monocytes/macrophages.Q43611931
Targeting dendritic cells--why bother?Q43892663
A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancerQ44370683
Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cellsQ44662354
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study.Q44743006
Imatinib mesylate impairs Flt3L-mediated dendritic cell expansion and antitumor effects in vivoQ44771609
Survival with AGS-003, an autologous dendritic cell-based immunotherapy, in combination with sunitinib in unfavorable risk patients with advanced renal cell carcinoma (RCC): Phase 2 study resultsQ35504499
Phase I pilot study of Wilms tumor gene 1 peptide-pulsed dendritic cell vaccination combined with gemcitabine in pancreatic cancerQ35538449
Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells.Q35563824
TOR in the immune systemQ35621941
NK cell compartments and their activation by dendritic cellsQ35634241
Immunoregulatory T cells in tumor immunityQ35692166
Manipulating dendritic cell biology for the active immunotherapy of cancerQ35825249
Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli.Q35834680
HER-2 pulsed dendritic cell vaccine can eliminate HER-2 expression and impact ductal carcinoma in situ.Q35899068
Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host DiseaseQ35904666
Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancerQ36228550
Decreased tumor surveillance in perforin-deficient miceQ36367528
Maturation, activation, and protection of dendritic cells induced by double-stranded RNAQ36367830
Gamma delta T cells provide an early source of interferon gamma in tumor immunityQ36371404
The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancerQ36371644
Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myelomaQ36407085
Sipuleucel-T (APC8015) for prostate cancerQ36613961
Treatment with proteasome inhibitor bortezomib enhances antigen-specific CD8+ T-cell-mediated antitumor immunity induced by DNA vaccinationQ36874310
Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7Q36910715
A Phase I vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer.Q36958112
Imatinib mesylate inhibits CD4+ CD25+ regulatory T cell activity and enhances active immunotherapy against BCR-ABL- tumorsQ36965879
Progression-free and overall survival in ovarian cancer patients treated with CVac, a mucin 1 dendritic cell therapy in a randomized phase 2 trialQ37024702
Antigens for cancer immunotherapy.Q37308133
Expression of the Classical and Nonclassical HLA Molecules in Breast CancerQ37394717
Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanomaQ37394755
Immune parameters affecting the efficacy of chemotherapeutic regimensQ37848665
Restoration of antitumor immunity through selective inhibition of myeloid derived suppressor cells by anticancer therapiesQ37875180
Combining immunotherapy and targeted therapies in cancer treatmentQ37995939
A review of B7-H3 and B7-H4 immune molecules and their role in ovarian cancer.Q38036543
Enhancing the anticancer effects of 5-fluorouracil: current challenges and future perspectivesQ38243924
Cytotoxic T lymphocyte antigen-4 blockade enhances antitumor immunity by stimulating melanoma-specific T-cell motilityQ38974152
Cetuximab ± chemotherapy enhances dendritic cell-mediated phagocytosis of colon cancer cells and ignites a highly efficient colon cancer antigen-specific cytotoxic T-cell response in vitro.Q39535140
Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte functionQ39692699
Clinical Benefit of Allogeneic Melanoma Cell Lysate-Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients.Q39765546
P433issue1
P921main subjectdendritic cellQ506253
P304page(s)161-173
P577publication date2017-03-01
P1433published inJournal of BiosciencesQ2092222
P1476titleImmune modulation by dendritic-cell-based cancer vaccines
P478volume42

Reverse relations

cites work (P2860)
Q91497028Cytolytic Activity of Effector T-lymphocytes Against Hepatocellular Carcinoma is Improved by Dendritic Cells Pulsed with Pooled Tumor Antigens
Q39415827Promising investigational drug candidates in phase I and phase II clinical trials for mesothelioma.
Q91898387Substantial remission of prostate adenocarcinoma with dendritic cell therapy APCEDEN® in combination with chemotherapy

Search more.