scholarly article | Q13442814 |
P356 | DOI | 10.1007/S12031-013-0022-8 |
P698 | PubMed publication ID | 23657982 |
P2093 | author name string | Bing Li | |
Dawei Yu | |||
Zhiying Xu | |||
P2860 | cites work | Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons | Q21262040 |
DJ-1 has a role in antioxidative stress to prevent cell death | Q24306633 | ||
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism | Q24321359 | ||
Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease | Q27335848 | ||
In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133 | Q28270649 | ||
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1 | Q28506681 | ||
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. | Q28593258 | ||
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease | Q28594269 | ||
Parkinson's disease | Q29616302 | ||
Parkinson's disease. First of two parts | Q29620416 | ||
BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity | Q33689625 | ||
High regulatability favors genetic selection in SLC18A2, a vesicular monoamine transporter essential for life. | Q33919434 | ||
Gain-of-function haplotypes in the vesicular monoamine transporter promoter are protective for Parkinson disease in women | Q34474458 | ||
Protective effect of the radical scavenger edaravone against methamphetamine-induced dopaminergic neurotoxicity in mouse striatum | Q34568490 | ||
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum. | Q34578581 | ||
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization | Q34836156 | ||
A randomized controlled clinical trial to compare the safety and efficacy of edaravone in acute ischemic stroke | Q35121559 | ||
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease | Q35660223 | ||
Toxic proteins released from mitochondria in cell death | Q35743127 | ||
Parkinsonism due to mutations in PINK1, parkin, and DJ-1 and oxidative stress and mitochondrial pathways | Q36186542 | ||
Molecular pathophysiology of Parkinson's disease | Q36196507 | ||
L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL. | Q36341135 | ||
Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6. | Q37485355 | ||
Parkinson disease: insights in clinical, genetic and pathological features of monogenic disease subtypes | Q37910371 | ||
Protective effect of edaravone against Alzheimer's disease-relevant insults in neuroblastoma N2a cells. | Q39249288 | ||
Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease. | Q39876870 | ||
DJ-1 modulates UV-induced oxidative stress signaling through the suppression of MEKK1 and cell death | Q40007595 | ||
DJ-1 decreases Bax expression through repressing p53 transcriptional activity | Q40043929 | ||
Assessment of cell viability in primary neuronal cultures | Q42168073 | ||
Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters | Q44418044 | ||
Antioxidant MCI-186 inhibits mitochondrial permeability transition pore and upregulates Bcl-2 expression | Q44484424 | ||
Effects of edaravone on reperfusion injury in patients with acute myocardial infarction | Q45027825 | ||
The novel free radical scavenger, edaravone, increases neural stem cell number around the area of damage following rat traumatic brain injury. | Q45933136 | ||
Treatment with edaravone, initiated at symptom onset, slows motor decline and decreases SOD1 deposition in ALS mice | Q46418017 | ||
Edaravone protects against MPP+ -induced cytotoxicity in rat primary cultured astrocytes via inhibition of mitochondrial apoptotic pathway | Q46471698 | ||
Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats | Q46514766 | ||
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease | Q46683999 | ||
Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage | Q46838344 | ||
Parkinson disease: from pathology to molecular disease mechanisms | Q48177704 | ||
Effects of a novel free radical scavenger, MCl-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model. | Q48719184 | ||
DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism | Q79249169 | ||
Long-term efficacy of edaravone in patients with acute myocardial infarction | Q79786705 | ||
P433 | issue | 2 | |
P921 | main subject | edaravone | Q335099 |
neurotoxicity | Q3338704 | ||
toxic encephalopathy | Q7830379 | ||
Parkinson's disease | Q11085 | ||
P304 | page(s) | 539-549 | |
P577 | publication date | 2013-05-10 | |
P1433 | published in | Journal of Molecular Neuroscience | Q15708870 |
P1476 | title | Edaravone prevents neurotoxicity of mutant L166P DJ-1 in Parkinson's disease | |
P478 | volume | 51 |
Q34412765 | Edaravone promotes functional recovery after mechanical peripheral nerve injury |
Q36323797 | Edaravone protects against hyperosmolarity-induced oxidative stress and apoptosis in primary human corneal epithelial cells |
Q38244581 | Edaravone's free radical scavenging mechanisms of neuroprotection against cerebral ischemia: review of the literature |
Q88574928 | Elevated expression of DJ-1 (encoded by the human PARK7 gene) protects neuronal cells from sevoflurane-induced neurotoxicity |
Q42416499 | Oxygen-glucose-deprived rat primary neural cells exhibit DJ-1 translocation into healthy mitochondria: a potent stroke therapeutic target |
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