Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer

scientific article published on 28 April 2013

Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10549-013-2542-X
P698PubMed publication ID23624778
P5875ResearchGate publication ID236459965

P50authorEmad A. RakhaQ55098175
Ian EllisQ55300055
Srinivasan MadhusudanQ56435835
Patrick J TigheQ56448978
Ola H NegmQ56942400
Andrew GreenQ55098173
P2093author name stringAlaa T Alshareeda
Christopher Nolan
Nada Albarakati
Rebeka Sultana
Ahmed Benhasouna
P2860cites workThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayQ22065419
The role of double-strand break repair — insights from human geneticsQ22122018
DNA double-strand breaks: signaling, repair and the cancer connectionQ28204231
RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumorsQ28253705
The mechanism of human nonhomologous DNA end joiningQ28257187
Association of BRCA1 with Rad51 in mitotic and meiotic cellsQ28302118
Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1.Q31095234
DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repairQ33947027
Role of non-homologous end joining (NHEJ) in maintaining genomic integrityQ34544982
DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repairQ34868235
Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaksQ35652566
A means to a DNA end: the many roles of Ku.Q35762470
Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancerQ35901185
Basal-like breast cancer: a critical reviewQ37167032
Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell lineQ41368190
Germline BRCA1 mutations and a basal epithelial phenotype in breast cancerQ42450903
Triple-negative breast cancer: distinguishing between basal and nonbasal subtypesQ42451354
BRCA1 dysfunction in sporadic basal-like breast cancerQ42502209
Expression of BRCA1 protein in breast cancer and its prognostic significanceQ42526565
Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancerQ44283662
The expression pattern of Ku correlates with tumor radiosensitivity and disease free survival in patients with rectal carcinomaQ44414853
Ku70 predicts response and primary tumor recurrence after therapy in locally advanced head and neck cancer.Q46546357
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectDNA damageQ5205747
P304page(s)301-310
P577publication date2013-04-28
P1433published inBreast Cancer Research and TreatmentQ326085
P1476titleClinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer
P478volume139

Reverse relations

cites work (P2860)
Q390031017B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells
Q37266446Abnormal DNA-PKcs and Ku 70/80 expression may promote malignant pathological processes in gastric carcinoma
Q64099911Apoptosis Induction byHistone Deacetylase Inhibitors in Cancer Cells: Role of Ku70
Q90398064Association Of GSTM1, GSTT1 And GSTP1 Polymorphisms With Breast Cancer Among Jordanian Women
Q35678658Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response
Q42496885Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein
Q38900933Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer
Q55261738Clinical values of Ku80 upregulation in superficial esophageal squamous cell carcinoma.
Q89967133Combination Therapy With Charged Particles and Molecular Targeting: A Promising Avenue to Overcome Radioresistance
Q64258395Comparative genomics sheds light on the predatory lifestyle of accipitrids and owls
Q35131267DNA damage response markers are differentially expressed in BRCA-mutated breast cancers
Q36792475Differences of Variable Number Tandem Repeats in XRCC5 Promoter Are Associated with Increased or Decreased Risk of Breast Cancer in BRCA Gene Mutation Carriers
Q92533625Genetic association of XRCC5 gene polymorphisms with breast cancer among Jordanian women
Q30239810Identification of Biomarkers for Breast Cancer Using Databases
Q36086823KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer
Q42016675Overexpression of Ku80 correlates with aggressive clinicopathological features and adverse prognosis in esophageal squamous cell carcinoma
Q53598546Overexpression of Ku80 suggests poor prognosis of locally advanced esophageal squamous cell carcinoma patients.
Q41715562Postoperative Radiotherapy Improves Survival in Stage pT2N0M0 Esophageal Squamous Cell Carcinoma with High Risk of Poor Prognosis
Q50437809Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer.
Q50457473Prognostic and biological significance of proliferation and HER2 expression in the luminal class of breast cancer.
Q41252181Prognostic significance of Ku80 in pT2N0M0 esophageal squamous cell carcinoma after Ivor-Lewis esophagectomy
Q38226307Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications
Q39019431SUMOylation proteins in breast cancer
Q35740074Selective Targeting to Glioma with Nucleic Acid Aptamers
Q55019644The Incidence of Other Primary Cancers in Patients with Cutaneous Lymphoma.
Q38690281The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer
Q45784223Transcriptional signature of lymphoblastoid cell lines of BRCA1, BRCA2 and non-BRCA1/2 high risk breast cancer families

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