Cell viability score (CVS) as a good indicator of critical concentration of benzalkonium chloride for toxicity in cultured ocular surface cell lines

scientific article published on April 2013

Cell viability score (CVS) as a good indicator of critical concentration of benzalkonium chloride for toxicity in cultured ocular surface cell lines is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YRTPH.2013.03.014
P698PubMed publication ID23557985
P5875ResearchGate publication ID236113298

P2093author name stringYoshimi Niwano
Masahiko Ayaki
Atsuo Iwasawa
P2860cites workRapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysQ25939005
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Incidence, severity and factors related to drug-induced keratoepitheliopathy with glaucoma medicationsQ33819802
Effectiveness of ophthalmic solution preservatives: a comparison of latanoprost with 0.02% benzalkonium chloride and travoprost with the sofZia preservative systemQ33879039
Corneal alternations induced by topical application of benzalkonium chloride in rabbitQ34056002
Preservatives in eyedrops: the good, the bad and the uglyQ34105511
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Toxicological evaluation of preservative-containing and preservative-free topical prostaglandin analogues on a three-dimensional-reconstituted corneal epithelium systemQ34997199
Conjunctival and corneal reactions in rabbits following short- and repeated exposure to preservative-free tafluprost, commercially available latanoprost and 0.02% benzalkonium chloride.Q36940995
Survey of ATCC stocks of human cell lines for hela contaminationQ37854683
Cell viability score as an integrated indicator for cytotoxicity of benzalkonium chloride-containing antiglaucoma eyedrops.Q39272712
Cell viability of four corneoconjunctival cell lines exposed to five preservatives and a surfactant used for infection control in eyedrops.Q39468311
Cytotoxicity assays of new artificial tears containing 2-methacryloyloxyethyl phosphorylcholine polymer for ocular surface cellsQ39492528
Modulation of the canonical Wnt pathway by Benzalkonium Chloride in corneal epitheliumQ39548837
Effect of timolol with and without preservative on the basal tear turnover in glaucomaQ39708297
Characterization of human corneal epithelial cell model as a surrogate for corneal permeability assessment: metabolism and transportQ39883337
Expression of ABC-transporters in human corneal tissue and the transformed cell line, HCE-T.Q40143803
In vitro comparison of cytoprotective and antioxidative effects of latanoprost, travoprost, and bimatoprost on conjunctiva-derived epithelial cells.Q40348422
Comparison of morphological and functional characteristics of primary-cultured human conjunctival epithelium and of Wong-Kilbourne derivative of Chang conjunctival cell lineQ40598432
Effect of benzalkonium chloride on the stability of the precorneal tear film in rabbit and manQ41681520
An in vivo confocal microscopy analysis of effects of topical antiglaucoma therapy with preservative on corneal innervation and morphologyQ42448654
Toxicity determined in vitro by morphological alterations and neutral red absorptionQ42816423
Multiple endpoint analysis of the 3D-reconstituted corneal epithelium after treatment with benzalkonium chloride: early detection of toxic damage.Q44435422
Prevalence of ocular surface disease in glaucoma patientsQ46389257
Evaluation of fungal and bacterial contaminations of patient-used ocular drops.Q46988616
Effects of benzalkonium chloride on the ocular surface of the rabbit.Q53250651
Polyquad-preserved travoprost/timolol, benzalkonium chloride (BAK)-preserved travoprost/timolol, and latanoprost/timolol in fixed combinations: a rabbit ocular surface studyQ57693342
Neutral red (NR) assay for cell viability and xenobiotic-induced cytotoxicity in primary cultures of human and rat hepatocytesQ67301456
The effect of epinephrine and benzalkonium chloride on cultured corneal endothelial and trabecular meshwork cellsQ69677771
Ocular symptoms and signs with preserved and preservative-free glaucoma medicationsQ80397112
Microbial contamination of multiply used preservative-free artificial tears packed in reclosable containersQ81948286
Surface chemistry study of the interactions of benzalkonium chloride with films of meibum, corneal cells lipids, and whole tearsQ83809306
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)177-183
P577publication date2013-04-01
P1433published inRegulatory Toxicology and PharmacologyQ2138805
P1476titleCell viability score (CVS) as a good indicator of critical concentration of benzalkonium chloride for toxicity in cultured ocular surface cell lines
P478volume66

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