ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma

scientific article published on 17 March 2013

ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10735-013-9504-9
P698PubMed publication ID23504200

P2093author name stringWei Wang
Jing Lan
Qin Shi
Honggeng Guan
Yang Lan
Zhiyi Cheng
Yehui Zhou
P2860cites workWnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradationQ24319714
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive mannerQ24320153
Frameshift mutations of Wnt pathway genes AXIN2 and TCF7L2 in gastric carcinomas with high microsatellite instabilityQ24337018
β-catenin/TCF-1 pathway in T cell development and differentiationQ26821842
Wnt/β-catenin signaling and diseaseQ26823272
Inhibition of oncogenic Wnt signaling through direct targeting of  -cateninQ27674587
Wnt/beta-catenin signaling in development and diseaseQ27860784
Positional information and the spatial pattern of cellular differentiationQ29616635
Cellular and molecular aspects of gastric cancer.Q34012910
Genetic susceptibility factors on genes involved in the steroid hormone biosynthesis pathway and progesterone receptor for gastric cancer riskQ34460484
Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesisQ35025086
E3 ubiquitin ligases as cancer targets and biomarkersQ35082710
Targeting E3 ubiquitin ligases for cancer therapy.Q35612694
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathwaysQ35641254
Variation in gene expression patterns in human gastric cancersQ35670324
Focus on gastric cancer.Q35681321
International variationQ35868021
Wnt signaling in development and diseaseQ37600117
Wnt signal transduction pathway and apoptosis: a reviewQ37768931
beta-Catenin/Wnt signaling regulates expression of the membrane type 3 matrix metalloproteinase in gastric cancerQ40285021
A finger on the pulse of Wnt receptor signalingQ42532344
Wnt signaling, stem cells, and cancer of the gastrointestinal tractQ42566173
Canonical Wnt signaling pathway plays an essential role in N-methyl-N-nitrosurea induced gastric tumorigenesis of miceQ43757323
Phase I study of combination therapy with peptide vaccine and anti-cancer drug for colorectal cancerQ46184385
The chemical basis of morphogenesis. 1953.Q46356837
A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.Q50335616
ß-catenin-independent noncanonical Wnt pathway might be induced in gastric cancersQ53294625
Mutations and nuclear accumulation of beta-catenin correlate with intestinal phenotypic expression in human gastric cancer.Q53583306
Upper gastrointestinal cancer risk in familial adenomatous polyposisQ54526466
The risk of upper gastrointestinal cancer in familial adenomatous polyposisQ67488531
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[Preliminary study of Peptide vaccine with UFT/LV as adjuvant setting for stage III colorectal cancer]Q83143566
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectadenocarcinomaQ356033
P304page(s)555-563
P577publication date2013-03-17
P1433published inJournal of Molecular HistologyQ2162212
P1476titleZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma
P478volume44

Reverse relations

cites work (P2860)
Q64105262Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma
Q98289234Functional roles of E3 ubiquitin ligases in gastric cancer
Q36939031Identification of 42 Genes Linked to Stage II Colorectal Cancer Metastatic Relapse.
Q26822956Keeping Wnt signalosome in check by vesicular traffic
Q38536557Novel Insights into the Genetics and Pathophysiology of Adrenocortical Tumors
Q37161336Pleiotropy between genetic markers of obesity and risk of prostate cancer
Q39029239RSPO2-LGR5 signaling has tumour-suppressive activity in colorectal cancer.
Q28082575Role of E3 ubiquitin ligases in gastric cancer
Q28086989Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review
Q27680931Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for Signaling
Q38441242The effect of host genetics on the gut microbiome
Q35300556Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells
Q26766683Ubiquitin proteasome system research in gastrointestinal cancer
Q33570215Whole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma.
Q39298488ZNRF3 Inhibits the Invasion and Tumorigenesis in Nasopharyngeal Carcinoma Cells by Inactivating the Wnt/β-Catenin Pathway
Q38831235ZNRF3 contributes to the growth of lung carcinoma via inhibiting Wnt/β-catenin pathway and is regulated by miR-93.
Q53685195ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.
Q38736941ZNRF3 is downregulated in papillary thyroid carcinoma and suppresses the proliferation and invasion of papillary thyroid cancer cells
Q38761277ZnRF3 Induces Apoptosis of Gastric Cancer Cells by Antagonizing Wnt and Hedgehog Signaling
Q45006367miR-146a promotes growth of osteosarcoma cells by targeting ZNRF3/GSK-3β/β-catenin signaling pathway

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