Genome-wide screening reveals that miR-195 targets the TNF-α/NF-κB pathway by down-regulating IκB kinase alpha and TAB3 in hepatocellular carcinoma

scientific article published on 26 June 2013

Genome-wide screening reveals that miR-195 targets the TNF-α/NF-κB pathway by down-regulating IκB kinase alpha and TAB3 in hepatocellular carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.26378
P698PubMed publication ID23487264
P5875ResearchGate publication ID236043439

P50authorXianghuo HeQ39051788
P2093author name stringJinjun Li
Ying Wang
Jie Ding
Yingjun Zhao
Qifeng Wang
Qi Tian
Chao Ge
Linhui Liang
Shenglin Huang
Ruopeng Zha
Taoyang Chen
Haibing Shi
P2860cites workMicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiationQ34079793
Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancerQ34166724
miR-301a as an NF-κB activator in pancreatic cancer cellsQ34485753
MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1.Q34786558
MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasionQ35760644
NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcomaQ37311506
IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharideQ40646108
Silencing of hsa-miR-124 by EVI1 in cell lines and patients with acute myeloid leukemia.Q42380741
MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells.Q44738304
Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound SubstrateQ55919356
Chromosomal allelic imbalance evolving from liver cirrhosis to hepatocellular carcinomaQ57205467
Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemiaQ60197192
Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular CarcinomaQ61645725
microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cellsQ84780931
Identification of differentially expressed microRNAs in human male breast cancerQ21261330
TAB3, a new binding partner of the protein kinase TAK1Q24530663
miR-15 and miR-16 induce apoptosis by targeting BCL2Q24536069
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaQ24539231
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3BQ24564757
Identification of a human NF-kappaB-activating protein, TAB3Q24621651
MicroRNAs in NF-kappaB signalingQ24630097
MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancerQ24632636
Role of the TAB2-related protein TAB3 in IL-1 and TNF signalingQ24633992
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasisQ24649156
Inflammation and cancerQ24649640
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responsesQ24670080
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.Q28118359
Duration of nuclear NF-kappaB action regulated by reversible acetylationQ28215080
miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancerQ28249659
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activationQ28252726
Introduction to NF-kappaB: players, pathways, perspectivesQ28271022
miR-146a suppresses invasion of pancreatic cancer cellsQ28272101
Signaling to NF-kappaBQ29547844
Nuclear factor-kappaB in cancer development and progressionQ29547879
The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwideQ29616215
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shockQ29619768
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanismQ29619866
Inflammation meets cancer, with NF-κB as the matchmakerQ29620242
Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cellsQ33609716
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
positive regulation of I-kappaB kinase/NF-kappaB signalingQ14864035
TNFQ18032037
TGF-beta activated kinase 1 (MAP3K7) binding protein 3Q21112827
Component of inhibitor of nuclear factor kappa B kinase complexQ21130508
P304page(s)654-666
P577publication date2013-06-26
P1433published inHepatologyQ15724398
P1476titleGenome-wide screening reveals that miR-195 targets the TNF-α/NF-κB pathway by down-regulating IκB kinase alpha and TAB3 in hepatocellular carcinoma
P478volume58

Reverse relations

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