Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia

scientific article published on 28 March 2017

Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/MP.2017.33
P932PMC publication ID5495879
P698PubMed publication ID28348379

P50authorPer SvenningssonQ21175215
Paul GreengardQ309979
Gaute T. EinevollQ11971645
Ole A. AndreassenQ31229142
Srdjan DjurovicQ34568432
Tuomo Mäki-MarttunenQ41046042
Olav B SmelandQ57081237
Anders M. DaleQ57693390
P2093author name stringY Wang
D Holland
C-H Chen
R S Desikan
L K McEvoy
A J Schork
W K Thompson
C-C Fan
A Devor
A Witoelar
P2860cites workRethinking schizophreniaQ22251086
Biological insights from 108 schizophrenia-associated genetic lociQ24561833
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysisQ24597718
GABAergic interneuron origin of schizophrenia pathophysiology.Q24597790
Five years of GWAS discoveryQ24610574
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptorQ24675924
The glial growth factors deficiency and synaptic destabilization hypothesis of schizophreniaQ24798030
Progress in the genetics of polygenic brain disorders: significant new challenges for neurobiologyQ27013601
Optogenetic pharmacology for control of native neuronal signaling proteinsQ27015715
Optogenetic approaches for dissecting neuromodulation and GPCR signaling in neural circuitsQ28071885
Heritability estimates for psychotic disorders: the Maudsley twin psychosis seriesQ28137629
Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortexQ28138248
Genome-wide association study identifies five new schizophrenia lociQ28248384
DISC1 at 10: connecting psychiatric genetics and neuroscienceQ28250914
Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in SchizophreniaQ28262977
Genome-wide association analysis identifies 13 new risk loci for schizophreniaQ28297287
The physiology, signaling, and pharmacology of dopamine receptorsQ28305030
Pleiotropy in complex traits: challenges and strategiesQ28390545
A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regionsQ28643908
Calcium signalling: dynamics, homeostasis and remodellingQ29547635
Spatio-temporal transcriptome of the human brainQ29614572
Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study.Q30366617
Pervasive sharing of genetic effects in autoimmune diseaseQ30431030
Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disordersQ30469044
N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: the final common pathway on the road to schizophrenia?Q30474021
The neurodevelopmental hypothesis of schizophrenia: following a trail of evidence from cradle to graveQ30615326
New statistical approaches exploit the polygenic architecture of schizophrenia--implications for the underlying neurobiologyQ30844089
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorderQ33470869
Shared common variants in prostate cancer and blood lipidsQ34001263
A polygenic burden of rare disruptive mutations in schizophreniaQ34060200
The neurobiology of slow synaptic transmissionQ34100272
Linking neurodevelopmental and synaptic theories of mental illness through DISC1Q34233683
Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapseQ34321656
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factorsQ34325802
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rateQ34342469
The Psychiatric GWAS Consortium: Big Science Comes to PsychiatryQ34350128
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsQ34498817
De novo mutations in schizophrenia implicate synaptic networksQ34540372
Computational psychiatry.Q34630298
From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatmentQ34632695
Modeling human cortical development in vitro using induced pluripotent stem cellsQ34639912
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPsQ34699776
The intense world syndrome--an alternative hypothesis for autismQ34871941
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene lociQ35168836
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathwaysQ35230796
Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32Q35356825
Abundant pleiotropy in human complex diseases and traits.Q35542127
DARPP-32: an integrator of neurotransmissionQ35639141
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D cultureQ35811877
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS.Q35903759
Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acidQ35941298
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locusQ35963497
Optical electrophysiology for probing function and pharmacology of voltage-gated ion channelsQ36027162
Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.Q36253911
From antipsychotic to anti-schizophrenia drugs: role of animal modelsQ36287726
Statistical connectivity provides a sufficient foundation for specific functional connectivity in neocortical neural microcircuitsQ36342487
Regulation of Ca(V)2 calcium channels by G protein coupled receptors.Q36565441
DREADDs for NeuroscientistsQ36595793
Electrical activity in early neuronal developmentQ36676053
Molecular profiling of antipsychotic drug function: convergent mechanisms in the pathology and treatment of psychiatric disordersQ36707022
Pathway analysis of seven common diseases assessed by genome-wide associationQ37014849
The challenge of connecting the dots in the B.R.A.I.N.Q37395958
The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms.Q37844408
Calcium signalling remodelling and diseaseQ37995715
Structure and function of the β subunit of voltage-gated Ca²⁺ channelsQ38043712
Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cellsQ38170728
Calcium signalling and psychiatric disease: bipolar disorder and schizophreniaQ38191819
Sensorimotor gating of the startle reflex: what we said 25 years ago, what has happened since then, and what comes nextQ38559394
Optical sensors to gain mechanistic insights into signaling assembliesQ38950115
Genome-Editing Technologies: Principles and ApplicationsQ39026438
A biophysically detailed model of neocortical local field potentials predicts the critical role of active membrane currentsQ39377429
A cellular mechanism for cortical associations: an organizing principle for the cerebral cortexQ39494445
Reconstruction and Simulation of Neocortical Microcircuitry.Q40320870
The computational anatomy of psychosisQ41199035
Application of cDNA microarrays to examine gene expression differences in schizophreniaQ43750661
Identification of Gene Loci That Overlap Between Schizophrenia and Educational AttainmentQ46090041
Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to valproic acidQ48101402
Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivoQ48170047
Behavioral phenotypes of Disc1 missense mutations in miceQ48178658
Hybrid Scheme for Modeling Local Field Potentials from Point-Neuron NetworksQ48449712
SchizophreniaQ55868331
Delineating novel signature patterns of altered gene expression in schizophrenia using gene microarrays.Q64905908
The human genome: gene expression profiling and schizophreniaQ74453170
Calcium signaling dysfunction in schizophrenia: a unifying approachQ79073580
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectschizophreniaQ41112
P304page(s)792-801
P577publication date2017-03-28
P1433published inMolecular PsychiatryQ6895973
P1476titleGenetic evidence for role of integration of fast and slow neurotransmission in schizophrenia
P478volume22

Reverse relations

cites work (P2860)
Q98166913A unified computational model for cortical post-synaptic plasticity
Q60949982Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations
Q64102599Attenuation of Novelty-Induced Hyperactivity of Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics
Q92799609Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
Q64945067Brain function, structure and genomic data are linked but show different sensitivity to duration of illness and disease stage in schizophrenia.
Q90732283Computational Modeling of Genetic Contributions to Excitability and Neural Coding in Layer V Pyramidal Cells: Applications to Schizophrenia Pathology
Q55180784Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder.
Q90172402Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia
Q52316128Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder.
Q56888533Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes
Q60460217Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Q38659979Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function
Q92595950Integrating genome-wide association study with regulatory SNP annotation information identified candidate genes and pathways for schizophrenia
Q50317783Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling.
Q47557531Psychiatric genetics and the structure of psychopathology.
Q46194843The Thymus/Neocortex Hypothesis of the Brain: A Cell Basis for Recognition and Instruction of Self.
Q96302720The polygenic architecture of schizophrenia - rethinking pathogenesis and nosology
Q90666112Use of tobacco in schizophrenia: A double-edged sword

articles: null.

Warning: Trying to access array offset on value of type null in /home/httpd/vhosts/renenyffenegger.ch/opendata.renenyffenegger.ch/Wikimedia/Wikidata/entity/main.php on line 1120 Warning: Trying to access array offset on value of type null in /home/httpd/vhosts/renenyffenegger.ch/opendata.renenyffenegger.ch/Wikimedia/Wikidata/entity/main.php on line 1120

Warning: foreach() argument must be of type array|object, null given in /home/httpd/vhosts/renenyffenegger.ch/opendata.renenyffenegger.ch/Wikimedia/Wikidata/entity/main.php on line 1122

Search more.