Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse.

scientific article

Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PATH.4165
P698PubMed publication ID23299523
P5875ResearchGate publication ID234153663

P50authorMarie JeanssonQ51804803
Gavin I WelshQ56862920
Ingeborg HersQ57337371
Lorna J HaleQ60061966
Samantha F MooreQ61148267
Claire M PerksQ61993753
P2093author name stringJ M Holly
P W Mathieson
M A Saleem
A J Murphy
J A Hurcombe
R J Coward
S N Hardouin
P2860cites workAngiopoietin-1 is essential in mouse vasculature during development and in response to injuryQ24629743
Molecular and cellular aspects of the insulin-like growth factor I receptorQ28288023
The relationship between proteinuria and coronary risk: a systematic review and meta-analysisQ33378672
Signalling through IGF-I and insulin receptors: where is the specificity?Q34783548
The mesangial cell revisited: no cell is an islandQ34983116
Cell biology of the glomerular podocyteQ35035937
HIV-associated renal disorders: recent insights into pathogenesis and treatment.Q36223895
Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of actionQ36254770
The role of insulin-like growth factor binding proteins.Q36626462
Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cellsQ36924959
Therapeutic targets in focal and segmental glomerulosclerosisQ37228164
Podocyte loss and progressive glomerular injury in type II diabetesQ37362675
The podocyte cytoskeleton--key to a functioning glomerulus in health and diseaseQ37949258
The insulin-like growth factor system in kidney disease and hypertension.Q37962116
Biology and significance of signalling pathways activated by IGF-II.Q37963987
Expression and localization of insulin-like growth factor binding proteins in normal and proteinuric kidney glomeruliQ38339676
Establishment of conditionally immortalized human glomerular mesangial cells in culture, with unique migratory properties.Q39038233
Role of insulin-like growth factor 1 receptor and c-Src in endothelin-1- and angiotensin II-induced PKB phosphorylation, and hypertrophic and proliferative responses in vascular smooth muscle cellsQ39759936
Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell linesQ39889648
Conditionally immortalized human glomerular endothelial cells expressing fenestrations in response to VEGF.Q40300487
The human glomerular podocyte is a novel target for insulin actionQ40357961
Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signalingQ40851705
Beck-Wiedemann syndrome and Wilms' tumour.Q41547507
Insulin signaling to the glomerular podocyte is critical for normal kidney functionQ42110064
Insulin/IGF-1 hybrid receptor expression on human platelets: consequences for the effect of insulin on platelet functionQ43264426
Expression of insulin-like growth factor I (IGF-I) and IGF-II mRNA during hepatic development, proliferation and carcinogenesis in the rat.Q45060671
Targeted gene knockdown in zebrafish reveals distinct intraembryonic functions for insulin-like growth factor II signaling.Q46011427
Insulin-like growth factors inhibit podocyte apoptosis through the PI3 kinase pathway.Q46393310
Insulin-like growth factor binding protein-2 modulates podocyte mitogenesisQ47647078
Genetic engineering of glomerular sclerosis in the mouse via control of onset and severity of podocyte-specific injury.Q51531177
The induction of a specific protease for insulin-like growth factor binding protein-3 in the circulation during severe illnessQ51609674
Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival.Q52027611
Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.Q53661064
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
Insulin-like growth factors and cancerQ56336667
Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated ratQ57740883
Urinary excretion of IGFBP-1 and -3 correlates with disease activity and differentiates focal segmental glomerulosclerosis and minimal change diseaseQ58177773
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)95-106
P577publication date2013-03-21
P1433published inJournal of PathologyQ400296
P1476titleInsulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse
P478volume230

Reverse relations

cites work (P2860)
Q91968184Altered Brain Expression of Insulin and Insulin-Like Growth Factors in Frontotemporal Lobar Degeneration: Another Degenerative Disease Linked to Dysregulation of Insulin Metabolic Pathways
Q91991368Expression of Glutamate Receptor Subtype 3 Is Epigenetically Regulated in Podocytes under Diabetic Conditions
Q35086477Glomerular endothelial cell injury and cross talk in diabetic kidney disease
Q41827044Insulin directly stimulates VEGF-A production in the glomerular podocyte
Q35285585Insulin signaling: implications for podocyte biology in diabetic kidney disease
Q49159738New insights into mechanisms of glomerular injury and repair from the 10th International Podocyte Conference 2014.
Q26766118Podocytes
Q33821237Podocytes, signaling pathways, and vascular factors in diabetic kidney disease
Q47885313Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor.
Q26743407Role of Receptor Tyrosine Kinase Signaling in Renal Fibrosis
Q38176169Signal transduction in podocytes--spotlight on receptor tyrosine kinases

Search more.