Aging of bone marrow mesenchymal stromal/stem cells: Implications on autologous regenerative medicine

scientific article

Aging of bone marrow mesenchymal stromal/stem cells: Implications on autologous regenerative medicine is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3233/BME-171624
P698PubMed publication ID28372278

P2093author name stringL Zhang
N de Isla
Y P Li
Y Y Li
L Targa
J F Stoltz
H Z Han
J S Ye
N Charif
P2860cites workAging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cellsQ46286017
Effect of donor age on the growth in vitro of cells obtained from human trabecular boneQ47578048
mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells.Q47823442
Patients with primary osteoarthritis show no change with ageing in the number of osteogenic precursors.Q50852537
Skeletal progenitor cells and ageing human populations.Q50873506
Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells.Q52119168
Oxidative stress induces senescence in human mesenchymal stem cells.Q54384642
Upregulation of p16INK4A promotes cellular senescence of bone marrow-derived mesenchymal stem cells from systemic lupus erythematosus patients.Q54495613
Stem Cells and Regenerative Medicine: Myth or Reality of the 21th CenturyQ26795447
Aging: a theory based on free radical and radiation chemistryQ27860549
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statementQ27861120
In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential of mesenchymal stem cells reveals a complex hierarchy of lineage commitmentQ28272235
Lack of telomerase activity in human mesenchymal stem cellsQ30164727
Replicative senescence of mesenchymal stem cells: a continuous and organized processQ33336408
Aging and replicative senescence have related effects on human stem and progenitor cellsQ33464937
Long term culture of mesenchymal stem cells in hypoxia promotes a genetic program maintaining their undifferentiated and multipotent statusQ33857675
How to track cellular aging of mesenchymal stromal cells?Q33896770
Reduced reactivation from dormancy but maintained lineage choice of human mesenchymal stem cells with donor age.Q33995621
Telomere length, stem cells and agingQ34689235
Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapiesQ34744250
Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cellsQ34768188
The composition of the mesenchymal stromal cell compartment in human bone marrow changes during development and agingQ35717741
Aging of mesenchymal stem cellsQ36323407
Age-related intrinsic changes in human bone-marrow-derived mesenchymal stem cells and their differentiation to osteoblastsQ36681378
Hypoxic culture conditions for Mesenchymal Stromal/Stem Cells from Wharton's jelly: a critical parameter to consider in a therapeutic contextQ39024220
Human mesenchymal stem cells efficiently manage oxidative stressQ39716782
Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells.Q39843440
Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their qualityQ45856815
Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiateQ45863683
Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansionQ45877573
P433issues1
P921main subjectregenerative medicineQ1061415
P304page(s)S57-S63
P577publication date2017-01-01
P1433published inBio-Medical Materials and EngineeringQ15746681
P1476titleAging of bone marrow mesenchymal stromal/stem cells: Implications on autologous regenerative medicine
P478volume28

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cites work (P2860)
Q89447778Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing
Q47643280Low-intensity pulsed ultrasound activates ERK1/2 and PI3K-Akt signalling pathways and promotes the proliferation of human amnion-derived mesenchymal stem cells.
Q90181998Mesenchymal Stem Cell Derived Extracellular Vesicles in Aging
Q52698412Mesenchymal Stem Cells as New Therapeutic Agents for the Treatment of Primary Biliary Cholangitis.
Q91893537Potential biological therapies for severe preeclampsia: a systematic review and meta-analysis
Q92351043Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure
Q54112596Reactive Oxygen Species, Superoxide Dimutases, and PTEN-p53-AKT-MDM2 Signaling Loop Network in Mesenchymal Stem/Stromal Cells Regulation.
Q55560176Suppression of T cells by mesenchymal and cardiac progenitor cells is partly mediated via extracellular vesicles.

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