Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction

scientific article

Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TAAP.2012.12.010
P698PubMed publication ID23274515
P5875ResearchGate publication ID234011171

P2093author name stringLu Wang
Wei Chen
Qiang Xu
Yan Shen
Ran Song
Yang Sun
Yan-Hong Gu
Xian-Ying Fang
Guang-Zhi Zeng
Jun-Ting Fan
Ning-Hua Tan
Xue-Feng Wu
P2860cites workRelevance of breast cancer cell lines as models for breast tumours: an updateQ28242046
Role of extracellular matrix renal tubulo-interstitial nephritis antigen (TINag) in cell survival utilizing integrin (alpha)vbeta3/focal adhesion kinase (FAK)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B-serine/threonine kinase (AKT) signalQ35310728
Isolation and antitumor activity of cyclic hexapeptides isolated from Rubiae radixQ71350509
P433issue1
P921main subjectmitochondrionQ39572
apoptotic processQ14599311
P304page(s)95-103
P577publication date2012-12-26
P1433published inToxicology and Applied PharmacologyQ2446974
P1476titlePlant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction
P478volume267

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cites work (P2860)
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Q48095070Cytotoxicity Study of Cyclopentapeptide Analogues of Marine Natural Product Galaxamide towards Human Breast Cancer Cells.
Q37290902Design and Synthesis of Analogues of Marine Natural Product Galaxamide, an N-methylated Cyclic Pentapeptide, as Potential Anti-Tumor Agent in Vitro
Q41680122Evaluating the cytotoxicity of flaxseed orbitides for potential cancer treatment.
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Q45065366In Silico Design of Anticancer Peptides
Q39063793Induction of apoptosis by total flavonoids from Scutellaria barbata D. Don in human hepatocarcinoma MHCC97-H cells via the mitochondrial pathway
Q47404057Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Q55352989Natural cyclopeptide RA-V inhibits the NF-κB signaling pathway by targeting TAK1.
Q38883994PRL-3 Promotes the Malignant Progression of Melanoma via Triggering Dephosphorylation and Cytoplasmic Localization of NHERF1.
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Q37729117d-Amino Acid Position Influences the Anticancer Activity of Galaxamide Analogs: An Apoptotic Mechanism Study

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